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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2036 [new locus tag: NWMN_RS11760 ]
  • pan locus tag?: SAUPAN005428000
  • symbol: NWMN_2036
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2036 [new locus tag: NWMN_RS11760 ]
  • symbol: NWMN_2036
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2253593..2254786
  • length: 1194
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGACAAATAATGGTAATGAGCCGAACTTAACGTTAAGTGATTTATATGACAAAGATGTT
    GTCTATACGTCAAGACCTTCGTATATATCGAATCCATGGTTGAAACCGGACGAACATCAA
    TCTAATTTTTTAACTGGTAGGGAGTTATTAATAGCAAATCAATTACCTGTTATTGTTCAC
    GAAGCTAGTGCGACAGACAAATTGCATCAGCTATTTCAAGTTATTGGTAAGGAAGTACCG
    AACTCAATTTATACATTTAACAATCAGCAATCTTACGAAAACTTGATCAAACAATTGGCA
    CATAAGGAAAATAAAAAGATTTATTTTCAATATATTCATGATGAAACAATCTTGAATCAG
    CAATATTATGCATTAGATAAAACGTTATTTGTTGCTTTAAATAATAAAGCAAGAATACCT
    GAATGGACAAATGGGAAGTTTTTACCAAAAAGAAAAGTTGTAAAAATTGAGCAATTCGAA
    AACGAGATTAAGAATTGGGAATTCCCGTTAGTAATTAAGCCGGGAGATGATCTTCCGACA
    GCAGGTGGCTATGGCGTTATGATTTGTTATCATGATGCAGATTTACAAAAAGCGATAACG
    CGTATTAAAGAGGCAACTGCTGAAACGAATTCGCTTATTATCGAACAGAAGATTGAAGAA
    AAAGCGAATTATTGCGTTCAGTTTGCATACTCGGAATCGCTAGGCATTCAATATCTTGGT
    GCGGCAACGCAATTAACGGATAAGTACGGATTTTATAACGGAAATGAAAATACTACTAAT
    GTACCAGAGCACGTTATAGAAGCAGGTAGACAAATTATGGAAAACGGTGTGAATCAAGGA
    TTCTTTGGTGTAGCTGGTTTTGACCTACTCGTCGATGAGGATGATAACGTTTATGCGATT
    GATTTAAACTTTAGACAAAATGGTTCAACGAGCATGTTATTACTTGCTAACGAGTTGAAT
    TCAGGATATCAAAAGTTTTATAGTTATCATTCAAAAGGTGATAACACACATTTCTTCAAT
    ACGATTTTGAAATATGTCAAAGAAGGTAGTTTATACCCGTTATCTTATTATGATGGTGAT
    TGGTACGGTGAAGATAAAGTTAAATCAAGGTTTGGCTGTATTTGGCATGGTGATTCAAAA
    GAAACAGTACTGGAGAATGAACGCGCATTTTTAGCTGAACTTGAACACTATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1194

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_2036 [new locus tag: NWMN_RS11760 ]
  • symbol: NWMN_2036
  • description: hypothetical protein
  • length: 397
  • theoretical pI: 4.91145
  • theoretical MW: 45645.7
  • GRAVY: -0.537783

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Fatty acid and phospholipid metabolism Biosynthesis acetyl-CoA carboxylase, biotin carboxylase subunit (TIGR00514; EC 6.3.4.14; HMM-score: 11.2)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    ATP-grasp (CL0179) ATP-grasp_4; ATP-grasp domain (PF13535; HMM-score: 19.9)
    Peptidase_CA (CL0125) Peptidase_C101; Peptidase family C101 (PF16218; HMM-score: 16.1)
    and 2 more
    no clan defined DUF3182; Protein of unknown function (DUF3182) (PF11379; HMM-score: 15.9)
    ATP-grasp (CL0179) CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain (PF02786; HMM-score: 13.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004537
    • TAT(Tat/SPI): 0.000646
    • LIPO(Sec/SPII): 0.000764
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTNNGNEPNLTLSDLYDKDVVYTSRPSYISNPWLKPDEHQSNFLTGRELLIANQLPVIVHEASATDKLHQLFQVIGKEVPNSIYTFNNQQSYENLIKQLAHKENKKIYFQYIHDETILNQQYYALDKTLFVALNNKARIPEWTNGKFLPKRKVVKIEQFENEIKNWEFPLVIKPGDDLPTAGGYGVMICYHDADLQKAITRIKEATAETNSLIIEQKIEEKANYCVQFAYSESLGIQYLGAATQLTDKYGFYNGNENTTNVPEHVIEAGRQIMENGVNQGFFGVAGFDLLVDEDDNVYAIDLNFRQNGSTSMLLLANELNSGYQKFYSYHSKGDNTHFFNTILKYVKEGSLYPLSYYDGDWYGEDKVKSRFGCIWHGDSKETVLENERAFLAELEHY

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY (repression) regulon
    CodY(TF)important in Amino acid metabolism; RegPrecise    transcription unit transferred from N315 data RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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