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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS02385 [old locus tag: NWMN_0422 ]
  • pan locus tag?: SAUPAN002170000
  • symbol: NWMN_RS02385
  • pan gene symbol?: —
  • synonym:
  • product: carboxylesterase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS02385 [old locus tag: NWMN_0422 ]
  • symbol: NWMN_RS02385
  • product: carboxylesterase
  • replicon: chromosome
  • strand: +
  • coordinates: 473298..474032
  • length: 735
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (473298..474032) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0422

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAGAATTAAAACACCGAGTCCATCGTATTTAAAAGGCACAAATGGACATGCGATATTA
    TTATTACATTCATTTACAGGTACAAATCGGGATGTGAAGCATCTTGCAGCTGAGTTAAAT
    GACCAAGGATTTAGTTGTTATGCACCGAATTATCCAGGTCATGGTTTATTGTTGAAAGAT
    TTCATGACATATAATGTAGATGATTGGTGGGAAGAAGTTGAGAAAGCTTACCAATTTTTA
    GTCAATGAAGGTTATGAATCTATCAGTGCAACGGGTGTGTCTTTAGGTGGATTAATGACA
    TTAAAATTGGCGCAACACTATCCTTTGAAACGTATCGCTGTCATGTCAGCACCAAAGGAA
    AAGAGTGACGATGGCTTAATAGAACATTTAGTTTATTATAGTCAACGCATGTCGAATATT
    TTAAATTTAGATCAGCAAGCATCGAGTGCGCAATTAGCAGCAATTGATGATTATGAAGGT
    GAAATTACGAAGTTTCAACATTTTATTGATGATATCATGACAAATTTAAATGTTATTAAA
    ATGCCAGCTAATATATTATTTGGTGGTAAAGATGCGCCATCCTATGAAACAAGTGCACAT
    TTTATTTATGAACATTTAGGATCAGTAGACAAAGAATTAAATGGTCTGAAGGATTCGCAT
    CATTTAATGACGCATGGAGAAGGCAGAGATATTTTAGAAGAAAATGTTATTCGCTTTTTC
    AATGCTTTAACATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    735

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS02385 [old locus tag: NWMN_0422 ]
  • symbol: NWMN_RS02385
  • description: carboxylesterase
  • length: 244
  • theoretical pI: 5.48333
  • theoretical MW: 27442.8
  • GRAVY: -0.312295

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (TIGR03695; EC 4.2.99.20; HMM-score: 31.9)
    and 6 more
    Metabolism Energy metabolism Other 3-oxoadipate enol-lactonase (TIGR02427; EC 3.1.1.24; HMM-score: 22.2)
    exosortase A system-associated hydrolase 2 (TIGR03101; HMM-score: 20.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Biotin pimelyl-[acyl-carrier protein] methyl ester esterase (TIGR01738; EC 3.1.1.85; HMM-score: 20.5)
    Metabolism Energy metabolism Photosynthesis putative magnesium chelatase accessory protein (TIGR03056; HMM-score: 17.3)
    cyanobacterial long protein repeat (TIGR02059; HMM-score: 16.8)
    Plasmodium subtelomeric family (TIGR01607; HMM-score: 12.2)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    AB_hydrolase (CL0028) Hydrolase_4; Serine aminopeptidase, S33 (PF12146; HMM-score: 55.7)
    and 7 more
    Abhydrolase_6; Alpha/beta hydrolase family (PF12697; HMM-score: 29.4)
    Abhydrolase_1; alpha/beta hydrolase fold (PF00561; HMM-score: 19.8)
    DLH; Dienelactone hydrolase family (PF01738; HMM-score: 17.8)
    UPF0227; Uncharacterised protein family (UPF0227) (PF05728; HMM-score: 14.3)
    Esterase; Putative esterase (PF00756; HMM-score: 13.2)
    Peptidase_S9; Prolyl oligopeptidase family (PF00326; HMM-score: 12.3)
    DUF2048; Abhydrolase domain containing 18 (PF09752; HMM-score: 12)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.129448
    • TAT(Tat/SPI): 0.018088
    • LIPO(Sec/SPII): 0.025088
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MRIKTPSPSYLKGTNGHAILLLHSFTGTNRDVKHLAAELNDQGFSCYAPNYPGHGLLLKDFMTYNVDDWWEEVEKAYQFLVNEGYESISATGVSLGGLMTLKLAQHYPLKRIAVMSAPKEKSDDGLIEHLVYYSQRMSNILNLDQQASSAQLAAIDDYEGEITKFQHFIDDIMTNLNVIKMPANILFGGKDAPSYETSAHFIYEHLGSVDKELNGLKDSHHLMTHGEGRDILEENVIRFFNALT

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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