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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS03335 [old locus tag: NWMN_0583 ]
- pan locus tag?: SAUPAN002478000
- symbol: NWMN_RS03335
- pan gene symbol?: —
- synonym:
- product: HAD family hydrolase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS03335 [old locus tag: NWMN_0583 ]
- symbol: NWMN_RS03335
- product: HAD family hydrolase
- replicon: chromosome
- strand: +
- coordinates: 664635..665354
- length: 720
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGGATTTGAATCAAATTAAAGCAGTTGTATTTGATTTAGAAGGTACGTTGTTGGACAGA
GTTAAATCTCGAGAGAAATTTATCGAAGAGCAATATGAACGATTTCATGACTACTTAATT
CATGTTCAACTGGCAGATTTTAAAAAAGCATTTATTGAGCTAGATGACGATGAAGATAAT
GATAAACCTGATTTATATAAAGAAATCATTAAACGTTTCCATGTAGATAGGTTAACTTGG
AAAGACTTATTTAATGATTTTGAAATGCATTTTTATCGTTATGTATTTCCTTATTACGAT
ACTTTGTATACACTAGAAAAGCTATCGCAAAAAGGCTTTCAAATTGGTGTTATCGCAAAT
GGTAAATCTAAGATTAAACAATTTCGATTACATTCACTTGGTTTGATGCATGTTATTAAT
TATTTATCAACATCAGAAACAGTTGGTTTTCGTAAACCACATCCTAAAATTTTTGAAGAT
ATGATTGATCAACTAGGGGTATTACCTGAGCAAATTATGTATGTTGGCGATGATGCGTTA
AATGATGTAGCTCCAGCACGAGCTATGGGCATGGTTAGTGTATGGTATAAACAAGAAGAT
GCTGAAATTGAACCACTCGAAGAAGAAGTTGATTTTACAATTACAACAGTGGAAGAATTA
TTAACCATTTTACCAATAAAAAATGATAATAAAGGAGAAAATTATGGATCTATTTACTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS03335 [old locus tag: NWMN_0583 ]
- symbol: NWMN_RS03335
- description: HAD family hydrolase
- length: 239
- theoretical pI: 4.54953
- theoretical MW: 28196.9
- GRAVY: -0.401255
⊟Function[edit | edit source]
- TIGRFAM: HAD hydrolase, TIGR02253 family (TIGR02253; HMM-score: 125.6)and 25 moreHAD hydrolase, REG-2-like, family IA (TIGR02252; HMM-score: 80.2)noncanonical pyrimidine nucleotidase, YjjG family (TIGR02254; EC 3.1.3.5; HMM-score: 77.8)haloacid dehalogenase, type II (TIGR01428; EC 3.8.1.2; HMM-score: 70.5)Energy metabolism Sugars phosphoglycolate phosphatase, bacterial (TIGR01449; EC 3.1.3.18; HMM-score: 61.4)Unknown function Enzymes of unknown specificity HAD hydrolase, family IIIA (TIGR01662; HMM-score: 52.4)Unknown function Enzymes of unknown specificity HAD hydrolase, family IA, variant 1 (TIGR01549; HMM-score: 50.8)AHBA synthesis associated protein (TIGR01454; HMM-score: 50.3)epoxide hydrolase N-terminal domain-like phosphatase (TIGR02247; HMM-score: 48.2)Unknown function Enzymes of unknown specificity HAD hydrolase, family IA, variant 3 (TIGR01509; HMM-score: 40.3)beta-phosphoglucomutase family hydrolase (TIGR02009; HMM-score: 39)HAD phosphatase, family IIIA (TIGR01668; EC 3.1.3.-; HMM-score: 35)Unknown function Enzymes of unknown specificity HAD hydrolase, TIGR01458 family (TIGR01458; HMM-score: 32.7)Energy metabolism Biosynthesis and degradation of polysaccharides beta-phosphoglucomutase (TIGR01990; EC 5.4.2.6; HMM-score: 31.1)pyrimidine 5'-nucleotidase (TIGR01993; EC 3.1.3.5; HMM-score: 27.1)Unknown function Enzymes of unknown specificity HAD hydrolase, family IIA (TIGR01460; HMM-score: 26.4)HAD hydrolase, family IA, variant 2 (TIGR01493; HMM-score: 25.5)HAD hydrolase, TIGR01548 family (TIGR01548; HMM-score: 23.3)histidinol-phosphate phosphatase domain (TIGR01656; HMM-score: 22.6)Central intermediary metabolism Other phosphonoacetaldehyde hydrolase (TIGR01422; EC 3.11.1.1; HMM-score: 17.9)phosphoglycolate/pyridoxal phosphate phosphatase family (TIGR01452; EC 3.1.3.18; HMM-score: 17.1)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family (TIGR01670; EC 3.1.3.45; HMM-score: 16.7)HAD hydrolase, TIGR01459 family (TIGR01459; HMM-score: 16)HAD phosphatase, family IIIC (TIGR01681; HMM-score: 14.1)phosphoserine phosphatase-like hydrolase, archaeal (TIGR01491; HMM-score: 14)Unknown function Enzymes of unknown specificity HAD hydrolase, TIGR01457 family (TIGR01457; HMM-score: 12.3)
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: HAD (CL0137) HAD_2; haloacid dehalogenase-like hydrolase (PF13419; HMM-score: 99.4)and 4 moreHydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 56.2)Hydrolase_like; HAD-hyrolase-like (PF13242; HMM-score: 33.6)PNK3P; Polynucleotide kinase 3 phosphatase (PF08645; HMM-score: 19)PGP_phosphatase; Mitochondrial PGP phosphatase (PF09419; HMM-score: 17.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.000776
- TAT(Tat/SPI): 0.000142
- LIPO(Sec/SPII): 0.000144
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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