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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS03420 [old locus tag: NWMN_0600 ]
  • pan locus tag?: SAUPAN002502000
  • symbol: NWMN_RS03420
  • pan gene symbol?: —
  • synonym:
  • product: sodium:proton antiporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS03420 [old locus tag: NWMN_0600 ]
  • symbol: NWMN_RS03420
  • product: sodium:proton antiporter
  • replicon: chromosome
  • strand: +
  • coordinates: 678669..680711
  • length: 2043
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (678669..680711) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0600

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    TTGGAAATATTTGAAACAATTCTTATATTTATAGCTGTTGTGATACTAAGTTCGTTTGTC
    CATACTTTCATACCTAAAGTACCCCTAGCATTTATACAAATTTTCTTGGGCATGTTACTA
    TTTATTACCCCAATCCCTGTTCAATTTAATTTTGATTCTGAATTGTTTATGGTAACAATG
    ATTGCGCCTTTGTTATTTGTAGAAGGTGTTAATGTTTCTAGAGTCCATTTAAGGAAATAT
    ATTAAGCCAGTGATGATGATGGCATTAGGATTAGTCATTACTACTGTGATAGGTGTAGGT
    TTATTTATTCATTGGATTTGGCCAGATTTACCTATTGGAGCAGCATTTGCAATTGCTGCC
    ATTCTTTGTCCTACTGATGCAGTAGCAGTGCAAGCAATCACTAAAGGAAAGGTCTTGCCA
    AAAGGAGCAATGACAATTCTTGAAGGTGAGTCATTATTGAATGATGCTGCTGGTATTATT
    TCATTTAAAATAGCTGTTGGAGTATTAGTTACAGGTGCTTTTTCACTTGTTGATGCTGTT
    CAGTTGTTTTTAATTGCATCAATTGGTGGCGCAGTGGTTGGTTTACTTATAGGTATGGCA
    TTAGTAAGGTTCCGATTAACATTGATGCGTCGAGGATATGAAAACATTAATATGTTTACA
    ATTATTCAATTGTTAACACCATTTGTTACGTATTTAATTGCTGAATTGTTTCACGCATCA
    GGAATCATTGCAGCAGTAGTTGCAGGACTTGTACATGGTTTCGAACGTGACAGAATTATG
    CAAGTACGTACACAACTGCAAATGAGTTACAATCATACATGGAATATACTAGGTTATGTT
    TTAAATGGCTTTGTTTTTTCAATATTAGGATTTTTAGTACCTGAAGTTATTATTAAAATT
    ATCAAAACAGAACCGCACAATTTAATCTTTTTAATAGGCATCACTATTGTTGTTGCTTTA
    GCTGTCTATCTATTTAGATTTGTTTGGGTTTATGTCTTATATCCTTATTTTTATTTAGCC
    ATCAGTCCATTCCAAAAAATGATGACTAAAAATGATGATGATAATCCAACGACTGAGAAA
    CCACCAAAGCGAAGTTTATACGCTTTAATTATGACGTTATGTGGTGTGCATGGAACAATT
    TCTTTAGCAATCGCATTAACGTTACCGTATTTTTTAGCAGGGCATCATGCTTTTACGTAT
    AGAAACGACTTATTATTTATTGCATCTGGTATGGTTATTATTAGTTTGGTAGTTGCACAA
    GTATTATTGCCATTATTAACGAAACCTGCACCTAAAACAGTAATTGGCAATATGTCGTTT
    AAAGTTGCTAGAATTTATATATTAGAACAAGTTATTGATTATCTAAATCAAAAATCTACT
    TTCGAAACAAGTTTTAAATATGGTAACGTGATTAAAGAATATCATGATAAATTAGCATTT
    TTAAAAACTGTAGAGAAAGATGATGAAAACTCTAAAGAATTAGAACGTCTACAAAAAATT
    GCTTTTAATGTAGAAACAAAAACATTAGAGTCTTTAGTAGATGAAGGACAAATAACGAAT
    AGTGTACTTGAAAACTATATGCGTTATGCTGAAAGAACACAGGTATATAGACAAGCATCA
    TTAATAAGAAGAATGATTGTATTATTACGAGGTGCTTTATTAAAACGAAGAGTACAAACG
    AGAGTGAACTCCGCATCTTCACTTAGTGTTACGGATAACTTAATGGAATTAAATAAAATT
    AATAAATTAGTCCATTATAATGTGGTTAGTCGTTTGTCTAAGGAAACAACAAAAGATAAT
    ACACTTGAAGTTGGAATGGTTTGTGACGGTTATTTAATGCGAATTGAAAACTTAACACCA
    TCAAATTTCTTCAACTCAGCAAGTGAAGATACGATTACTAAAATTAAATTAAATGCATTG
    AGAGAACAACGTCGCATTTTACGTGAGTTGATTGATACAGATGAAGTATCAGAAGGTACA
    GCGTTAAAACTAAGAGAAGCCATCAATTATGATGAAATGGTTATTGTAGATAGTATGACG
    TAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2043

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS03420 [old locus tag: NWMN_0600 ]
  • symbol: NWMN_RS03420
  • description: sodium:proton antiporter
  • length: 680
  • theoretical pI: 8.97345
  • theoretical MW: 76423.1
  • GRAVY: 0.506618

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds Na+/H+ antiporter (TIGR00831; HMM-score: 257.8)
    and 2 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds sodium/hydrogen exchanger 3 (TIGR00840; HMM-score: 50.7)
    Metabolism Transport and binding proteins Cations and iron carrying compounds sodium/hydrogen antiporter (TIGR00844; HMM-score: 7.2)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    CPA_AT (CL0064) Na_H_Exchanger; Sodium/hydrogen exchanger family (PF00999; HMM-score: 175.2)
    and 1 more
    no clan defined Trans_coact; Phage late-transcription coactivator (PF16805; HMM-score: 14.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 13
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004983
    • TAT(Tat/SPI): 0.000998
    • LIPO(Sec/SPII): 0.011714
  • predicted transmembrane helices (TMHMM): 13

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MEIFETILIFIAVVILSSFVHTFIPKVPLAFIQIFLGMLLFITPIPVQFNFDSELFMVTMIAPLLFVEGVNVSRVHLRKYIKPVMMMALGLVITTVIGVGLFIHWIWPDLPIGAAFAIAAILCPTDAVAVQAITKGKVLPKGAMTILEGESLLNDAAGIISFKIAVGVLVTGAFSLVDAVQLFLIASIGGAVVGLLIGMALVRFRLTLMRRGYENINMFTIIQLLTPFVTYLIAELFHASGIIAAVVAGLVHGFERDRIMQVRTQLQMSYNHTWNILGYVLNGFVFSILGFLVPEVIIKIIKTEPHNLIFLIGITIVVALAVYLFRFVWVYVLYPYFYLAISPFQKMMTKNDDDNPTTEKPPKRSLYALIMTLCGVHGTISLAIALTLPYFLAGHHAFTYRNDLLFIASGMVIISLVVAQVLLPLLTKPAPKTVIGNMSFKVARIYILEQVIDYLNQKSTFETSFKYGNVIKEYHDKLAFLKTVEKDDENSKELERLQKIAFNVETKTLESLVDEGQITNSVLENYMRYAERTQVYRQASLIRRMIVLLRGALLKRRVQTRVNSASSLSVTDNLMELNKINKLVHYNVVSRLSKETTKDNTLEVGMVCDGYLMRIENLTPSNFFNSASEDTITKIKLNALREQRRILRELIDTDEVSEGTALKLREAINYDEMVIVDSMT

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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