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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS03665 [old locus tag: NWMN_0645 ]
  • pan locus tag?: SAUPAN002560000
  • symbol: NWMN_RS03665
  • pan gene symbol?:
  • synonym:
  • product: N-acetyltransferase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS03665 [old locus tag: NWMN_0645 ]
  • symbol: NWMN_RS03665
  • product: N-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 728291..728734
  • length: 444
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (728291..728734) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0645

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAGGACACTTAATAAAGATGAACATAATTATATCAAGCAAATAGCTAATATACATGAG
    ACATTATTGTCGCAAGTAGAATCCAACTATAAATGTACTAAACTGAGTATTGCTCTTAGG
    TACGAGATGATATGTTCAAGATTAAAACATACAAATGATAAAATTTATATATATGAAAAT
    GAAGGTCAATTAATAGCGTTTATTTGGGGACATTTTAGTAATGAAAAAAGTATGGTTAAC
    ATTGAACTGCTATATGTTGAACCACAATTTCGCAAACTGGGAATAGCTACGCAACTGAAG
    ATTGCGCTTGAAAAATGGGCAAAAACTATGAATGCAAAGCGAATAAGCAATACAATTCAT
    AAAAATAATTTGCCAATGATATCTTTGAATAAAGATTTAGGTTATCAAGTGAGTCATGTG
    AAAATGTATAAAGATATTGATTAG
    60
    120
    180
    240
    300
    360
    420
    444

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS03665 [old locus tag: NWMN_0645 ]
  • symbol: NWMN_RS03665
  • description: N-acetyltransferase
  • length: 147
  • theoretical pI: 9.65915
  • theoretical MW: 17319
  • GRAVY: -0.440816

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 26.5)
    and 2 more
    Cellular processes Cellular processes Adaptations to atypical conditions diaminobutyrate acetyltransferase (TIGR02406; EC 2.3.1.178; HMM-score: 15.1)
    putative beta-lysine N-acetyltransferase (TIGR03827; EC 2.3.1.-; HMM-score: 14.7)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 45.7)
    and 7 more
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 36.4)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 25.4)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 21.2)
    FR47; FR47-like protein (PF08445; HMM-score: 18.9)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 17.8)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 13.1)
    Acetyltransf_13; ESCO1/2 acetyl-transferase (PF13880; HMM-score: 12.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016444
    • TAT(Tat/SPI): 0.000342
    • LIPO(Sec/SPII): 0.002091
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRTLNKDEHNYIKQIANIHETLLSQVESNYKCTKLSIALRYEMICSRLKHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKRISNTIHKNNLPMISLNKDLGYQVSHVKMYKDID

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]