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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS05495 [old locus tag: NWMN_0981 ]
  • pan locus tag?: SAUPAN003343000
  • symbol: NWMN_RS05495
  • pan gene symbol?: ctaB
  • synonym:
  • product: protoheme IX farnesyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS05495 [old locus tag: NWMN_0981 ]
  • symbol: NWMN_RS05495
  • product: protoheme IX farnesyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 1090462..1091373
  • length: 912
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (1090462..1091373) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0981

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAGCAAAGAGCATACTTTGTCACAAAATATTAGCAGAGTTAACTTCAAAGAATTGCAA
    CAGATAATTAAAATGGGACTTGTTCAAGGTAACTTAATTCCGGCTTTTGCGGGCGCATGG
    CTAGCAGTTGTAATGACAAATCATTCCTTCTTATCATCAATACCTCAAATTTTATTAATG
    CTATTTGGATCTACTTTAATTATGGGTGGCGCATGTGCGTTAAATAATTATTACGACCAA
    GATATTGATCGTATTATGCCTAGTAAACAAAATAGACCAACTGTAAATAATAGAATTACA
    GATCAAAATTTATTACTATTAAGTTTTGGTATGATGTTAGTTGGAGAAATTTGTTTGTTT
    TTATTGAATATACCATCAGGCGTACTTGGTCTTATGGGGATTGTAGGTTATGTGTCTTAT
    TACTCAATATGGTCTAAAAGACATACAACATGGAACACAGTGATTGGGAGTTTTCCTGGA
    GCAGTACCACCACTAATTGGATGGGTTGCAATTGAAGGACAAATTAGTTTAACAGCGATT
    GCGCTGTTTTTAGTTGTATTTTGTTGGCAACCAATTCATTTTTATGCCTTAGCTATTAAA
    CGTAAAGATGAATATGCACTTGCAAATATTCCAATGTTACCATCAGTTAAGGGCTTTAAA
    CGTACACGTGTCAGTATGTTTATCTGGTTGATTATTTTATTGCCAGTACCTTTATTACTA
    ATAAATTTAGGTGTCGTATTCGTAGTGTTAGCTACATTATTAAATTTAGGATGGATTGCA
    TTAGGTTTAACAACATTTAAGAAAAATTCAGATCAAACAAAATGGGCAACACAAATGTTT
    ATATATTCACTAAATTATTTAGTGATCTTTTTCGTGTTAGCTGTGATTGTTTCATTACTT
    ACTTTGATCTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    912

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS05495 [old locus tag: NWMN_0981 ]
  • symbol: NWMN_RS05495
  • description: protoheme IX farnesyltransferase
  • length: 303
  • theoretical pI: 9.93909
  • theoretical MW: 33858.4
  • GRAVY: 0.735644

⊟Function[edit | edit source]

  • reaction:
    EC 2.5.1.-?  ExPASy
  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin protoheme IX farnesyltransferase (TIGR01473; EC 2.5.1.-; HMM-score: 318.5)
    and 2 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 4-hydroxybenzoate polyprenyl transferase (TIGR01474; EC 2.5.1.-; HMM-score: 62.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone putative 4-hydroxybenzoate polyprenyltransferase (TIGR01475; EC 2.5.1.-; HMM-score: 39.1)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Terp_synthase (CL0613) UbiA; UbiA prenyltransferase family (PF01040; HMM-score: 189.5)
    and 3 more
    no clan defined TrbL; TrbL/VirB6 plasmid conjugal transfer protein (PF04610; HMM-score: 19)
    DUF4577; Domain of unknown function (DUF4577) (PF15145; HMM-score: 12.7)
    DUF3671; Protein of unknown function (PF12420; HMM-score: 7.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008034
    • TAT(Tat/SPI): 0.0009
    • LIPO(Sec/SPII): 0.002076
  • predicted transmembrane helices (TMHMM): 8

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLFGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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