Jump to navigation
Jump to search
NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL1125 [new locus tag: SACOL_RS05745 ]
- pan locus tag?: SAUPAN003343000
- symbol: ctaB
- pan gene symbol?: ctaB
- synonym:
- product: protoheme IX farnesyltransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL1125 [new locus tag: SACOL_RS05745 ]
- symbol: ctaB
- product: protoheme IX farnesyltransferase
- replicon: chromosome
- strand: +
- coordinates: 1137416..1138327
- length: 912
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3237824 NCBI
- RefSeq: YP_185989 NCBI
- BioCyc: see SACOL_RS05745
- MicrobesOnline: 912593 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901ATGAGCAAAGAGCATACTTTGTCACAAAATATTAGCAGAGTTAACTTCAAAGAATTGCAA
CAGATAATTAAAATGGGACTTGTTCAAGGTAACTTAATTCCGGCTTTTGCGGGCGCATGG
CTAGCAGTTGTAATGACAAATCATTCCTTCTTATCATCAATACCTCAAATTTTATTAATG
CTATTTGGATCTACTTTAATTATGGGTGGCGCATGTGCGTTAAATAATTATTACGACCAA
GATATTGATCGTATTATGCCTAGTAAACAAAATAGACCAACTGTAAATAATAGAATTACA
GATCAAAATTTATTACTATTAAGTTTTGGTATGATGTTAGTTGGAGAAATTTGTTTGTTT
TTATTGAATATACCATCAGGCGTACTTGGTCTTATGGGGATTGTAGGTTATGTGTCTTAT
TACTCAATATGGTCTAAAAGACATACAACATGGAACACAGTGATTGGGAGTTTTCCTGGA
GCAGTACCACCACTAATTGGATGGGTTGCAATTGAAGGACAAATTAGTTTAACAGCGATT
GCGCTGTTTTTAGTTGTATTTTGTTGGCAACCAATTCATTTTTATGCCTTAGCTATTAAA
CGTAAAGATGAATATGCACTTGCAAATATTCCAATGTTACCATCAGTTAAGGGCTTTAAA
CGTACACGTGTCAGTATGTTTATCTGGTTGATTATTTTATTGCCAGTACCTTTATTACTA
ATAAATTTAGGTGTCGTATTCGTAGTGTTAGCTACATTATTAAATTTAGGATGGATTGCA
TTAGGTTTAACAACATTTAAGAAAAATTCAGATCAAACAAAATGGGCAACACAAATGTTT
ATATATTCACTAAATTATTTAGTGATCTTTTTCGTGTTAGCTGTGATTGTTTCATTACTT
ACTTTGATCTAG60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
912
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL1125 [new locus tag: SACOL_RS05745 ]
- symbol: CtaB
- description: protoheme IX farnesyltransferase
- length: 303
- theoretical pI: 9.93909
- theoretical MW: 33858.4
- GRAVY: 0.735644
⊟Function[edit | edit source]
- reaction: EC 2.5.1.-? ExPASy
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin protoheme IX farnesyltransferase (TIGR01473; EC 2.5.1.-; HMM-score: 318.5)and 2 moreBiosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 4-hydroxybenzoate polyprenyl transferase (TIGR01474; EC 2.5.1.-; HMM-score: 62.2)Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone putative 4-hydroxybenzoate polyprenyltransferase (TIGR01475; EC 2.5.1.-; HMM-score: 39.1)
- TheSEED :
- Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB
Respiration Respiration - no subcategory Biogenesis of cytochrome c oxidases Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaBand 1 more - PFAM: Terp_synthase (CL0613) UbiA; UbiA prenyltransferase family (PF01040; HMM-score: 189.5)and 3 moreno clan defined TrbL; TrbL/VirB6 plasmid conjugal transfer protein (PF04610; HMM-score: 19)DUF4577; Domain of unknown function (DUF4577) (PF15145; HMM-score: 12.7)DUF3671; Protein of unknown function (PF12420; HMM-score: 7.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 9
- LocateP: Multi-transmembrane(Lipid modified N-termini)
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPII)
- Intracellular possibility: 0.17
- Signal peptide possibility: -1
- N-terminally Anchored Score: -1
- Predicted Cleavage Site: MGGACAL
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.008034
- TAT(Tat/SPI): 0.0009
- LIPO(Sec/SPII): 0.002076
- predicted transmembrane helices (TMHMM): 8
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLFGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
PLoS One: 2009, 4(12);e8176
[PubMed:19997597] [WorldCat.org] [DOI] (I e)