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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS08555 [old locus tag: NWMN_1523 ]
- pan locus tag?: SAUPAN004221000
- symbol: NWMN_RS08555
- pan gene symbol?: mnmA
- synonym:
- product: tRNA 2-thiouridine(34) synthase MnmA
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS08555 [old locus tag: NWMN_1523 ]
- symbol: NWMN_RS08555
- product: tRNA 2-thiouridine(34) synthase MnmA
- replicon: chromosome
- strand: -
- coordinates: 1688640..1689758
- length: 1119
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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1021
1081TTGTCAAATAAAGATATACGTGTTGTCGTTGGTATGTCAGGCGGTGTAGATAGTTCTGTA
ACAGCCCACGTCTTAAAAGAACAAGGTTATGATGTCATTGGCATATTTATGAAAAACTGG
GATGACACTGACGAAAATGGCGTATGTACTGCAACTGAAGATTACAACGATGTTATTGAA
GTGTGTAATCAAATTGGCATTCCGTATTACGCTGTTAATTTTGAAAAAGAATATTGGGAT
AAAGTCTTTACGTATTTCTTAGATGAATACAAAAAAGGTCGTACTCCAAATCCAGACGTT
ATGTGTAATAAAGAAATTAAGTTTAAAGCCTTTTTAGATCATGCGATGAATTTAGGTGCA
GATTATGTAGCAACAGGACATTACGCACGCATACATCGTCATGAAGATGGTCATGTTGAA
ATGTTACGTGGTGTAGATAATAATAAAGATCAAACATACTTCTTGAATCAATTATCTCAA
CAACAACTTTCAAAAGTGATGTTCCCAATTGGCGACATCGAAAAGAGTGAAGTGCGTCGA
ATTGCTGAAGAACAAGGACTTGTTACTGCTAAGAAAAAAGATTCTACAGGCATTTGTTTT
ATCGGCGAAAAAAACTTTAAAACATTTTTATCACAATATTTACCTGCACAACCGGGTGAT
ATGATAACACTTGATGGTAAGAAAATGGGTAAACATAGTGGTTTGATGTATTACACAATA
GGACAAAGACATGGATTAGGTATAGGTGGAGATGGCGATCCTTGGTTTGTTGTCGGTAAA
AACCTAAAAGATAATGTTTTATATGTAGAACAAGGATTCCATCACGATGCATTATACAGT
GATTACTTAATTGCTTCAGACTATTCATTTGTAAATCCAGAAGATAATGACTTAGATCAA
GGTTTTGAATGTACAGCTAAATTTAGATATCGCCAAAAAGATACGAAAGTTTTTGTGAAA
CGTGAAAACGACCATGCACTACGTGTTACTTTTGCTGAGCCAGTAAGAGCAATCACACCT
GGACAAGCAGTTGTTTTTTATCAAGGTGATGTGTGTCTTGGTGGTGCAACAATTGACGAT
GTGTTCAAAAATGAAGGTCAATTAAATTATGTTGTATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS08555 [old locus tag: NWMN_1523 ]
- symbol: NWMN_RS08555
- description: tRNA 2-thiouridine(34) synthase MnmA
- length: 372
- theoretical pI: 5.15955
- theoretical MW: 42150.2
- GRAVY: -0.457258
⊟Function[edit | edit source]
- ⊞reaction: EC 2.8.1.13? ExPASy
- ⊞TIGRFAM: Protein synthesis tRNA and rRNA base modification tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (TIGR00420; EC 2.1.1.61; HMM-score: 454.4)and 10 more
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- ⊞PFAM: HUP (CL0039) tRNA_Me_trans; tRNA methyl transferase (PF03054; HMM-score: 492.2)and 6 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊞Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊞Other Information[edit | edit source]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Artem Cherkasov, Michael Hsing, Roya Zoraghi, Leonard J Foster, Raymond H See, Nikolay Stoynov, Jihong Jiang, Sukhbir Kaur, Tian Lian, Linda Jackson, Huansheng Gong, Rick Swayze, Emily Amandoron, Farhad Hormozdiari, Phuong Dao, Cenk Sahinalp, Osvaldo Santos-Filho, Peter Axerio-Cilies, Kendall Byler, William R McMaster, Robert C Brunham, B Brett Finlay, Neil E Reiner
Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.
J Proteome Res: 2011, 10(3);1139-50
[PubMed:21166474] [WorldCat.org] [DOI] (I p)