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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS09740 [old locus tag: NWMN_1727 ]
  • pan locus tag?: SAUPAN004761000
  • symbol: NWMN_RS09740
  • pan gene symbol?:
  • synonym:
  • product: multidrug ABC transporter ATP-binding protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS09740 [old locus tag: NWMN_1727 ]
  • symbol: NWMN_RS09740
  • product: multidrug ABC transporter ATP-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1927584..1928807
  • length: 1224
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (1927584..1928807) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1727

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCGTAACCAAGCTACCACATTATTTAATAAAAGATTACATGCCCTTCGTAAAGAGAAA
    AATTATTATAATAAGTTTATATTTAATGGTCATTTCATGGTCTTTTTACTTATTTTGCTG
    GGTGCATTTATTTTTGGATATGGTGAATGGTTAAAACATATTCCAACGAATATCAATTTT
    TCATTAATAGCAGCAGTGATTGTTGCGTTGACATCTATTTTTCCAATGCGACCACTGTTA
    AAAGAAGCGGATAAAATCTTTTTATTACCATTTGAAAAACACATGTCTCAATTTATGCGT
    CATGCGATTTTATATAGTTACTTTGCGCGCATATTAATCCAACTCATTATTGTTATTGTA
    ATGTTCCCGTTGTTTTACAATATTAATCAACATAATGTGGCATTTTATATTTGTTTTGGA
    GTCAGTGCATTAATTTTTCCATATGTTGGTTTACGCTTAAGATGGCAATGGTATCAATCG
    GGACTTAAAACATGGCAAGTTAATTTAATATCATTCATCACCTTTGCTCTAACATATTAC
    TTACTATTAGCTCCAAAATGGTACATCGCATTTGTGATGGTTGCTTTGCCTGTGTTAATA
    GAATTTTTAGTTAAAAAATATAAACCAGGCTTTTTGTATCCTTGGGAGAAAATGATTGCA
    ATCGAACATCGACATCATATGAATTATTATAAATTTGTTAATATGTTCACCGATGTAAAA
    CATTTGAAAGAATCTGCAGTCAGAAGAAGTTATCTAGATATACTTTTACCAGTTCCAAAG
    GGTAGTAAATTTAACTCTAATGCGATGTATTTATTCTTATTTATTAGAAGCTTTATAAGA
    GGGAGAGACGCATTTAATATTATCTTTAGGTTAGTAATTATTGCAGTTTTATTAATGGTT
    TGGTTATCATATCCATTAGTGACAGCAATTATTGGGTGTTTATTTGTATATATTATATTG
    TTACAAATGGCACAATTTTATTCACAGCAAGCATATGGCTTATGGCCTCAAGTGTGGCCT
    GTACCTGAAGAGAAGGTAATCAAAGGGTATGAACAGTTTTTATATAGATTAATGTTTGTT
    ATTTGTACTGTGTTTGCAGTGACATTTATTATAAAACATATGACGTTATTCTATGTTGTA
    CTCATTTTCTATATTGTAGGTTTATTAACGATTAGAAGTATTATTAAAAAGTTGAAATAT
    CAGGAAACATTATTACGAGACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1224

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS09740 [old locus tag: NWMN_1727 ]
  • symbol: NWMN_RS09740
  • description: multidrug ABC transporter ATP-binding protein
  • length: 407
  • theoretical pI: 10.2763
  • theoretical MW: 48441.1
  • GRAVY: 0.617199

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined EcsB; Bacterial ABC transporter protein EcsB (PF05975; HMM-score: 354.6)
    and 1 more
    YbhQ; Putative inner membrane protein YbhQ (PF11076; HMM-score: 6.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00181
    • TAT(Tat/SPI): 0.000119
    • LIPO(Sec/SPII): 0.003213
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFIFGYGEWLKHIPTNINFSLIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHAILYSYFARILIQLIIVIVMFPLFYNINQHNVAFYICFGVSALIFPYVGLRLRWQWYQSGLKTWQVNLISFITFALTYYLLLAPKWYIAFVMVALPVLIEFLVKKYKPGFLYPWEKMIAIEHRHHMNYYKFVNMFTDVKHLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIRSFIRGRDAFNIIFRLVIIAVLLMVWLSYPLVTAIIGCLFVYIILLQMAQFYSQQAYGLWPQVWPVPEEKVIKGYEQFLYRLMFVICTVFAVTFIIKHMTLFYVVLIFYIVGLLTIRSIIKKLKYQETLLRD

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]