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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS12055 [old locus tag: NWMN_2081 ]
- pan locus tag?: SAUPAN005571000
- symbol: NWMN_RS12055
- pan gene symbol?: sfnaA
- synonym:
- product: MFS transporter
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS12055 [old locus tag: NWMN_2081 ]
- symbol: NWMN_RS12055
- product: MFS transporter
- replicon: chromosome
- strand: -
- coordinates: 2318441..2319634
- length: 1194
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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1141ATGACAAAATATTTTTTTAGCAGTTCTTTTCTACTATTTCTAGGTAATTGGATTGGACAA
ATAGGGCTAAATTGGTTTGTACTTACCACTTATCATAACGCAGTTTATCTGGGGATTGTC
AATTTTTGCAGACTTGTACCAATATTATTACTAAGTGTGTGGGCAGGGGCAATTGCCGAT
AAATATGATAAAGGGCGATTGCTGAGAATTACAATTTCATCATCATTTTTAGTAACTGCA
ATTTTATGTGTGCTCACGTATAGTTTCACTGCAATTCCAATTAGCGTCATTATTATATAT
GCGACATTAAGAGGGATTTTAAGTGCGGTTGAAACACCTTTAAGACAAGCAATCTTACCA
GATTTATCAGATAAAATATCTACTACACAAGCTGTATCATTTCATTCATTCATCATTAAT
ATTTGTCGTTCAATAGGGCCTGCCATTGCTGGTGTCATATTAGCAGTCTATCATGCGCCA
ACAACATTTCTTGCACAGGCAATTTGTTATTTTATCGCAGTTTTATTATGCTTACCATTA
CATTTTAAAGTAACTAAAATACCTGAAGATGCATCAAGATACATGCCGTTAAAAGTTATT
ATAGATTACTTCAAATTACATATGGAAGGTCGACAAATATTTATAACATCATTATTGATT
ATGGCGACAGGTTTTTCATATACGACACTTTTACCAGTTTTGACAAACAAAGTATTTCCG
GGGAAATCTGAAATATTTGGTATCGCTATGACGATGTGTGCCATTGGTGGTATTATTGCA
ACGCTAGTTTTACCTAAAGTACTTAAATATATTGGTATGGTAAATATGTATTATTTAAGT
TCATTTTTATTTGGCATTGCTTTGTTAGGTGTGGTATTTCACAATATTGTCATCATGTTC
ATTTGTATTACATTGATTGGGTTATTTAGTCAATGGGCACGTACGACAAATCGCGTTTAT
TTTCAAAATAATGTTAAAGATTATGAACGTGGTAAAGTACTGAGTATTATTATGATGGAT
AGAGGTATGATTCCATTGGGAAGTCTATTAATGAGTATATGTGCAGATGTGTTTGGCATT
GTTAGAACTTTTTCAATAATGGGAATAAGTACTATATGCATTACAATGGTATTCTATTTT
ATAAATAGAAAGTTGAAGTTAAAGTTGGAGGAAAGTAATCATGGTATATCTTGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS12055 [old locus tag: NWMN_2081 ]
- symbol: NWMN_RS12055
- description: MFS transporter
- length: 397
- theoretical pI: 9.65741
- theoretical MW: 44337.1
- GRAVY: 0.86801
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Cations and iron carrying compounds H+ Antiporter protein (TIGR00900; HMM-score: 123.6)and 1 moremultidrug resistance protein (TIGR00880; HMM-score: 31.4)
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: MFS (CL0015) MFS_3; Transmembrane secretion effector (PF05977; HMM-score: 141.6)and 2 moreMFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 100.5)MFS_2; MFS/sugar transport protein (PF13347; HMM-score: 13.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 12
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.009055
- TAT(Tat/SPI): 0.00056
- LIPO(Sec/SPII): 0.01214
- predicted transmembrane helices (TMHMM): 11
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTKYFFSSSFLLFLGNWIGQIGLNWFVLTTYHNAVYLGIVNFCRLVPILLLSVWAGAIADKYDKGRLLRITISSSFLVTAILCVLTYSFTAIPISVIIIYATLRGILSAVETPLRQAILPDLSDKISTTQAVSFHSFIINICRSIGPAIAGVILAVYHAPTTFLAQAICYFIAVLLCLPLHFKVTKIPEDASRYMPLKVIIDYFKLHMEGRQIFITSLLIMATGFSYTTLLPVLTNKVFPGKSEIFGIAMTMCAIGGIIATLVLPKVLKYIGMVNMYYLSSFLFGIALLGVVFHNIVIMFICITLIGLFSQWARTTNRVYFQNNVKDYERGKVLSIIMMDRGMIPLGSLLMSICADVFGIVRTFSIMGISTICITMVFYFINRKLKLKLEESNHGIS
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: Fur* see NWMN_2081
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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