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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS14080 [old locus tag: NWMN_2450 ]
- pan locus tag?: SAUPAN006212000
- symbol: NWMN_RS14080
- pan gene symbol?: feoB
- synonym:
- product: ferrous iron transporter B
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS14080 [old locus tag: NWMN_2450 ]
- symbol: NWMN_RS14080
- product: ferrous iron transporter B
- replicon: chromosome
- strand: -
- coordinates: 2693594..2695588
- length: 1995
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1981ATGGAAAATTATTGTATTTTAGGAAATCCTAATGTTGGTAAAACATCTTTGTTTAACGCT
TTAACTGGTTCGTATGAATATATAGGCAACTGGAGTGGCGTAACGGTAGAGAAAAAAGTA
GGGAAACTTAAAGAAAATGTAGGACAATTAATTGATTTACCAGGTACATATGATTTATCG
CCGATTTCTAAAGATGAAACTGTAGTGACAGACTATTTATTAAACGATTCATTTTCAGGA
ATCATTAACATTGTTGATGCGAGTCAACTAAAAAGAAATATGCAATTAACAGTACAATTG
TTAGAACTTAATCAACCAATATACATCGGATTAAATATGATTGATGTAGCTACAAAGCGC
GGGATAAAAATCGATTATCATAAATTGATGAAAAAGTTAAAAACACCTATTTTTCCAGTT
GTGGCACGTACAGGCAAAGGAACAAAATATTTACTTGGCGAAATAAAGCATCTAGGGGAA
GGGTATCAACCGCATTTTAAAATCAATTATGGTGAGAAGATTGAAGAGACAATTAAAAAT
ATGTGTCAAATAATAATGACAGAGACATCTCATGATAAGTATCAAGCTAGGTTTATTGCG
ATTCAATTCTTATTAAATAACATGCAAATTGCAAACGAACTTAATTCAGAGGTTGTAAAT
AAATTGTCGAGTTTACGTGATCAAGTTGCTGAACAAGTAGGGGCTGTATCTGTTCGTCGA
GAGATGGAGCGTATACGCAATCATTATATTGAGACGTTATTGCAAGACGTGGTAACGTAT
CCAGATGAAGATAAGCAATATTTCAGCTCTAGAATAGACAAGATATTAACACATAAATAT
ATAGGGATGCCTATCTTTCTAGCAATTATGTGGTTGATCTTTCAAACTACATTTACATGG
ATTGGCACACCTTTGTCGGATCAACTCGATGCATTTATAGGTGGTACATTTACAGATAGT
GTGAAGACGATTATGAATTATCTTGGTGTTATACCATTTTTACAAGATTTAATTACAGAT
GGCATTATTGCTGGTGTAGGATCAGTATTAGTCTTTGTACCACAAATTGTTGTGCTCTTT
TTCTTTATATCTTTATTAGAAGATTCGGGTTATATGGCACGTATTGCGGTTTTAATGGAT
CGTATTATGGAATCGTTCGGTTTAAGCGGGAAGTCTTTTATACCAATGATTATCGGATTT
GGTTGTAATGTACCGAGTATTATGGCTGCGCGCAGTATTGAAAATGAAAAAGAGCGTTTA
ACAACGATATTAATTGCACCATTCATGTCATGCTCTGCTAGACTGCCAGTGTATGCGTTG
TTCGTAGGTATCTTTTTCAAAGAGAATCAATCTTTAGTAGTATTAAGCCTGTATGTTTTA
GGTATTATTATGGCATTTTTAGTCAGTACAGTACTTACTAAGACGATTTTAAAAAATGAT
AATGCAATCTTTATTGTGGAATTGCCAACATACCGTGTGCCTTCCATTAAAACGTTGTGG
CGTAGTACTTGGGAAAAGGCTAAGGGCTTTGTTCGTAAAGCAGGTACATTTATTTTTGGC
GGCTCAGTAGTCATTTGGCTATTAAGTTATGTAGGACCACATGGTATCAATGTGAATATC
AATCAAAGTTTTTTACATATGGTTGGTAGTTTCTTTGGTATGTTAGTGCAACCGCTCGGA
TTTGGAACATGGCAAGCAGGTGCTACGTTAGTGCCAGGATTTTTAGCAAAAGAAGTTATC
GTAAGTTCGATGGCGATTATCTATTCATCAGGTGATGCAGGCCTTGTTAATGTGATTCAA
AATCAATTCACACCGCTATCTGCGTATGCATTTATGATATTTATACTATTGTATATTCCT
TGTGTTTCTACAGTAGCAGCAATCCGTAAAGAGACTTATTCATGGAAATGGACGGCACTT
GCAGTTGCCTATCCTCTAGTCACTGCATATGTCTTAACATTCATTTTTTATCAAGTCGGA
CATTTATTTGTTTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS14080 [old locus tag: NWMN_2450 ]
- symbol: NWMN_RS14080
- description: ferrous iron transporter B
- length: 664
- theoretical pI: 8.54816
- theoretical MW: 74384.8
- GRAVY: 0.367319
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Cations and iron carrying compounds ferrous iron transport protein B (TIGR00437; HMM-score: 624.7)and 10 moreUnknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 42.2)Protein synthesis Other ribosome-associated GTPase EngA (TIGR03594; HMM-score: 35.4)Protein synthesis Other ribosome biogenesis GTP-binding protein YlqF (TIGR03596; HMM-score: 27.6)Protein synthesis Other ribosome biogenesis GTP-binding protein YsxC (TIGR03598; HMM-score: 23.5)Protein fate Protein modification and repair [FeFe] hydrogenase H-cluster maturation GTPase HydF (TIGR03918; HMM-score: 21.3)Protein synthesis Other GTP-binding protein Era (TIGR00436; HMM-score: 21.1)Protein synthesis Other Obg family GTPase CgtA (TIGR02729; HMM-score: 17.8)Unknown function General GTP-binding protein YchF (TIGR00092; HMM-score: 15.4)Unknown function General GTP-binding protein HflX (TIGR03156; HMM-score: 11.5)Protein synthesis tRNA and rRNA base modification tRNA modification GTPase TrmE (TIGR00450; EC 3.6.-.-; HMM-score: 10.3)
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: P-loop_NTPase (CL0023) FeoB_N; Ferrous iron transport protein B (PF02421; HMM-score: 191.9)and 6 moreno clan defined Gate; Nucleoside recognition (PF07670; HMM-score: 152.3)FeoB_C; Ferrous iron transport protein B C terminus (PF07664; HMM-score: 67.9)P-loop_NTPase (CL0023) MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 56.1)SRPRB; Signal recognition particle receptor beta subunit (PF09439; HMM-score: 21.7)ATP_bind_1; Conserved hypothetical ATP binding protein (PF03029; HMM-score: 13.2)Peptidase_CA (CL0125) Transglut_core2; Transglutaminase-like superfamily (PF13369; HMM-score: 11.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 9
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.023195
- TAT(Tat/SPI): 0.000284
- LIPO(Sec/SPII): 0.003767
- predicted transmembrane helices (TMHMM): 10
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLKENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNMQLTVQLLELNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKYLLGEIKHLGEGYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEVVNKLSSLRDQVAEQVGAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKILTHKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQSLVVLSLYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSIKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQAGATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVSTVAAIRKETYSWKWTALAVAYPLVTAYVLTFIFYQVGHLFV
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: Fur*, SigB see NWMN_2450
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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