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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS14940 [old locus tag: NWMN_2609 ]
  • pan locus tag?: SAUPAN006486000
  • symbol: NWMN_RS14940
  • pan gene symbol?: noc
  • synonym:
  • product: nucleoid occlusion protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS14940 [old locus tag: NWMN_2609 ]
  • symbol: NWMN_RS14940
  • product: nucleoid occlusion protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2873009..2873848
  • length: 840
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (2873009..2873848) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_2609

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAAAAACCTTTTTCAAAATTATTTGGTTTGAAAAACAAAGATGACATCATTGGACAT
    ATTGAAGAAGATCGCAATAGTAATGTTGAATCCATTCAAATTGAACGTATCGTTCCCAAC
    CGTTATCAACCAAGACAGGTGTTTGAACCAAATAAAATTAAAGAACTTGCTGAATCAATA
    CATGAACATGGTTTACTACAACCTATTGTTGTAAGACCGATTGAAGAAGATATGTTTGAA
    ATTATTGCTGGAGAGCGCCGATTTAGAGCAATACAATCACTAAATTTACCTCAAGCAGAC
    GTTATTATTCGTGATATGGATGATGAAGAGACGGCTGTTGTTGCATTAATTGAGAATATT
    CAAAGAGAAAATTTGTCTGTTGTTGAAGAAGCGGAAGCCTATAAGAAATTATTGGAAATT
    GGTGATACAACGCAAAGTGAATTGGCAAAAAGTTTAGGTAAAAGTCAAAGCTTTATTGCA
    AATAAGTTGCGTTTATTGAAGTTGGCGCCGAAAGTACTACTTCGCTTAAGAGAAGGTAAA
    ATTACTGAACGTCATGCGAGAGCGGTATTATCATTGTCTGATAGCGAACAAGAAGCGTTG
    ATTGAGCAAGTCATTGCACAAAAGCTAAATGTGAAACAGACTGAAGATAGAGTACGCCAA
    AAAACGGGGCCCGAAAAAGTCAAAGCACAAAACCTTCGCTTTGCACAAGATGTCACTCAA
    GCACGAGATGAGGTAGGCAAAAGTATCCAAGCGATTCAACAAACAGGATTACATGTTGAG
    CATAAAGACAAAGATCATGAAGATTATTATGAAATAAAAATTCGAATATATAAACGTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS14940 [old locus tag: NWMN_2609 ]
  • symbol: NWMN_RS14940
  • description: nucleoid occlusion protein
  • length: 279
  • theoretical pI: 6.90987
  • theoretical MW: 32196.6
  • GRAVY: -0.620072

⊟Function[edit | edit source]

  • TIGRFAM:
    nucleoid occlusion protein (TIGR04285; HMM-score: 318)
    and 4 more
    ParB/RepB/Spo0J family partition protein (TIGR00180; HMM-score: 185.8)
    PRTRC system ParB family protein (TIGR03734; HMM-score: 140.9)
    Genetic information processing Mobile and extrachromosomal element functions Plasmid functions plasmid partitioning protein RepB (TIGR03454; HMM-score: 61.6)
    Signal transduction Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 14.8)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    ParBc (CL0248) ParBc; ParB-like nuclease domain (PF02195; HMM-score: 89.4)
    and 4 more
    HTH (CL0123) KorB; KorB domain (PF08535; HMM-score: 21.2)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 17.5)
    HTH_5; Bacterial regulatory protein, arsR family (PF01022; HMM-score: 14.4)
    HTH_3; Helix-turn-helix (PF01381; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006174
    • TAT(Tat/SPI): 0.000314
    • LIPO(Sec/SPII): 0.000923
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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