PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA0041 [new locus tag: SA_RS00350 ]
• pan locus tag^?: SAUPAN000106000
• symbol: xylR
• pan gene symbol^?: xylR
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA0041 [new locus tag: SA_RS00350 ]
• symbol: xylR
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 49752..50882
• length: 1131
• essential: no DEG

⊟Accession numbers

• Gene ID: 1122815 NCBI
• RefSeq: NP_373281 NCBI
• BioCyc: see SA_RS00350
• MicrobesOnline: 102307 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  481
  541
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  661
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  1021
  1081
  
  ATAAATGATAATGAAAAAAGAGTGCTAAGGGAAATTTATAACCATCATAATATTTCGCGT
  ACTCAAATATCTAAAAATCTTGAGATTAATAAGGCAACGATTTCTAGTATTTTGAATAAG
  TTAAAGTATAAATCTCTTGTTAATGAGGTTGGTGAGGGTGATAGCACGAAGAGTGGTGGT
  AGAAAACCTATTCTTCTGAAGGTTAATCATCTTTATGGTTATTTTATTTCTTTGGATTTA
  ACTTATAGTTCTGTTGAAGTGATGTACAATTATTTTGATGGTAATGTCATTAAGCATGAA
  TCTTATGATTTACCTGATGAAAAGGTTAGTAGTATATTAAGCATAATAAAAAAACATATT
  GATATTCAGGAGAAACTTGATACTTATAACGGACTATTAGGTGTGTCTGTTTCTATACAT
  GGAGTTGTGGATAATGAGCAGCATGTGACATATTTACCATTCCATGAAACTGAAGGAATT
  TCAATTGCTAAGAAAATAAAAGAAATTACTAATGTTCCAGTCGTAGTTGAAAATGAAGCG
  AATCTTTCAGCGTTATATGAACGTAATTTTAATCATAATTTATCCTACAATAATCTTATT
  GCTTTAAGTATACATAAAGGTATTGGTGCTGGGCTTATTATTAATAATCAATTGTATCGT
  GGTGCAAATGGGGAAGCGGGTGAAATTGGAAAAACACTTGTCTCAAAAGTTAGCGATAAT
  GTGGAGATCTTTCATAAGATTGAAGATATTTTTTCACAAGAAGCTTTACTGCATAATTTA
  AGTAATCAACTAAATGAGAAGATGACGCTTAGCAAATTAATTCAATTTTATAATGAAAAA
  AATCCAGTCGTAGTTGAAGAAATGGAACAATTTATAAATAAAATTGCTGTTTTAATACAT
  AATTTAAACACCCAGTTTAATCCGAATGCAATTTACATTAACTGTCCATTGTTCAATGAA
  ATGCCTGAAATATTAGAAGCAATTAAGAACCAGTTCAAACAATATTCACGTAACGAAATT
  CAAATAAAGTTAACATCTAATGTCAAATTTGCAACTTTGCTAGGTGGTACATTAGCAATT
  ATCCAAAAAGTACTACAGATTAATGATATTTACTTAGATATAAAAGCATAA
  60
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  1131
  

⊟Protein

• 4IJA
  PDB

Protein Data Bank: 4IJA

⊟General

• locus tag: SA0041 [new locus tag: SA_RS00350 ]
• symbol: XylR
• description: hypothetical protein
• length: 376
• theoretical pI: 6.71195
• theoretical MW: 42671.5
• GRAVY: -0.22234

⊟Function

• TIGRFAM:
  Unknown function General ROK family protein (putative glucokinase) (TIGR00744; HMM-score: 76.2)
  and 2 more
  Signal transduction Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 16.5)
  Signal transduction Regulatory functions DNA interactions TyrR family helix-turn-helix domain (TIGR04381; HMM-score: 12.4)
• TheSEED  :
  • Transcriptional regulator, ROK family
• PFAM:
  Actin_ATPase (CL0108) ROK; ROK family (PF00480; HMM-score: 117.5)
  and 14 more
  HTH (CL0123) MarR; MarR family (PF01047; HMM-score: 27.3)
  MarR_2; MarR family (PF12802; HMM-score: 21.5)
  HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 20.5)
  Fe_dep_repress; Iron dependent repressor, N-terminal DNA binding domain (PF01325; HMM-score: 19.7)
  TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 19.3)
  TFIIE_alpha; TFIIE alpha subunit (PF02002; HMM-score: 17.1)
  HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 16.7)
  Penicillinase_R; Penicillinase repressor (PF03965; HMM-score: 13.8)
  HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 13.7)
  HTH_3; Helix-turn-helix (PF01381; HMM-score: 13.3)
  Rrf2; Transcriptional regulator (PF02082; HMM-score: 12.9)
  Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 12.6)
  HTH_5; Bacterial regulatory protein, arsR family (PF01022; HMM-score: 12.4)
  no clan defined TraC_F_IV; F pilus assembly Type-IV secretion system for plasmid transfer (PF11130; HMM-score: 11.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.006092
  • TAT(Tat/SPI): 0.000792
  • LIPO(Sec/SPII): 0.000506
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 15925748 NCBI
• RefSeq: NP_373281 NCBI
• UniProt: A0A0H3JS71 UniProt

⊟Protein sequence

• MNDNEKRVLREIYNHHNISRTQISKNLEINKATISSILNKLKYKSLVNEVGEGDSTKSGGRKPILLKVNHLYGYFISLDLTYSSVEVMYNYFDGNVIKHESYDLPDEKVSSILSIIKKHIDIQEKLDTYNGLLGVSVSIHGVVDNEQHVTYLPFHETEGISIAKKIKEITNVPVVVENEANLSALYERNFNHNLSYNNLIALSIHKGIGAGLIINNQLYRGANGEAGEIGKTLVSKVSDNVEIFHKIEDIFSQEALLHNLSNQLNEKMTLSKLIQFYNEKNPVVVEEMEQFINKIAVLIHNLNTQFNPNAIYINCPLFNEMPEILEAIKNQFKQYSRNEIQIKLTSNVKFATLLGGTLAIIQKVLQINDIYLDIKA

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: no polycistronic organisation predicted

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications