PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS00350 [old locus tag: SA0041 ]
• pan locus tag^?: SAUPAN000106000
• symbol: SA_RS00350
• pan gene symbol^?: xylR
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS00350 [old locus tag: SA0041 ]
• symbol: SA_RS00350
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 49773..50882
• length: 1110
• essential: no DEG

⊟Accession numbers

• Location: NC_002745 (49773..50882) NCBI
• BioCyc: SA_RS00350 BioCyc
• MicrobesOnline: see SA0041

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  
  GTGCTAAGGGAAATTTATAACCATCATAATATTTCGCGTACTCAAATATCTAAAAATCTT
  GAGATTAATAAGGCAACGATTTCTAGTATTTTGAATAAGTTAAAGTATAAATCTCTTGTT
  AATGAGGTTGGTGAGGGTGATAGCACGAAGAGTGGTGGTAGAAAACCTATTCTTCTGAAG
  GTTAATCATCTTTATGGTTATTTTATTTCTTTGGATTTAACTTATAGTTCTGTTGAAGTG
  ATGTACAATTATTTTGATGGTAATGTCATTAAGCATGAATCTTATGATTTACCTGATGAA
  AAGGTTAGTAGTATATTAAGCATAATAAAAAAACATATTGATATTCAGGAGAAACTTGAT
  ACTTATAACGGACTATTAGGTGTGTCTGTTTCTATACATGGAGTTGTGGATAATGAGCAG
  CATGTGACATATTTACCATTCCATGAAACTGAAGGAATTTCAATTGCTAAGAAAATAAAA
  GAAATTACTAATGTTCCAGTCGTAGTTGAAAATGAAGCGAATCTTTCAGCGTTATATGAA
  CGTAATTTTAATCATAATTTATCCTACAATAATCTTATTGCTTTAAGTATACATAAAGGT
  ATTGGTGCTGGGCTTATTATTAATAATCAATTGTATCGTGGTGCAAATGGGGAAGCGGGT
  GAAATTGGAAAAACACTTGTCTCAAAAGTTAGCGATAATGTGGAGATCTTTCATAAGATT
  GAAGATATTTTTTCACAAGAAGCTTTACTGCATAATTTAAGTAATCAACTAAATGAGAAG
  ATGACGCTTAGCAAATTAATTCAATTTTATAATGAAAAAAATCCAGTCGTAGTTGAAGAA
  ATGGAACAATTTATAAATAAAATTGCTGTTTTAATACATAATTTAAACACCCAGTTTAAT
  CCGAATGCAATTTACATTAACTGTCCATTGTTCAATGAAATGCCTGAAATATTAGAAGCA
  ATTAAGAACCAGTTCAAACAATATTCACGTAACGAAATTCAAATAAAGTTAACATCTAAT
  GTCAAATTTGCAACTTTGCTAGGTGGTACATTAGCAATTATCCAAAAAGTACTACAGATT
  AATGATATTTACTTAGATATAAAAGCATAA
  60
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  1020
  1080
  1110
  

⊟Protein

• 4IJA
  PDB

Protein Data Bank: 4IJA

⊟General

• locus tag: SA_RS00350 [old locus tag: SA0041 ]
• symbol: SA_RS00350
• description: hypothetical protein
• length: 369
• theoretical pI: 6.71145
• theoretical MW: 41815.6
• GRAVY: -0.177236

⊟Function

• TIGRFAM:
  Unknown function General ROK family protein (putative glucokinase) (TIGR00744; HMM-score: 76.4)
  and 1 more
  Signal transduction Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 12.5)
• TheSEED: see SA0041
• PFAM:
  Actin_ATPase (CL0108) ROK; ROK family (PF00480; HMM-score: 117.5)
  and 11 more
  HTH (CL0123) MarR; MarR family (PF01047; HMM-score: 22.8)
  Fe_dep_repress; Iron dependent repressor, N-terminal DNA binding domain (PF01325; HMM-score: 18.2)
  MarR_2; MarR family (PF12802; HMM-score: 16)
  HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 15.3)
  TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 15.2)
  HTH_3; Helix-turn-helix (PF01381; HMM-score: 13.4)
  Rrf2; Transcriptional regulator (PF02082; HMM-score: 12.8)
  HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 12.8)
  HTH_5; Bacterial regulatory protein, arsR family (PF01022; HMM-score: 12.4)
  HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 12.4)
  no clan defined TraC_F_IV; F pilus assembly Type-IV secretion system for plasmid transfer (PF11130; HMM-score: 11.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.007075
  • TAT(Tat/SPI): 0.00045
  • LIPO(Sec/SPII): 0.000659
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446865875 NCBI
• RefSeq: WP_000943131 NCBI
• UniProt: see SA0041

⊟Protein sequence

• MLREIYNHHNISRTQISKNLEINKATISSILNKLKYKSLVNEVGEGDSTKSGGRKPILLKVNHLYGYFISLDLTYSSVEVMYNYFDGNVIKHESYDLPDEKVSSILSIIKKHIDIQEKLDTYNGLLGVSVSIHGVVDNEQHVTYLPFHETEGISIAKKIKEITNVPVVVENEANLSALYERNFNHNLSYNNLIALSIHKGIGAGLIINNQLYRGANGEAGEIGKTLVSKVSDNVEIFHKIEDIFSQEALLHNLSNQLNEKMTLSKLIQFYNEKNPVVVEEMEQFINKIAVLIHNLNTQFNPNAIYINCPLFNEMPEILEAIKNQFKQYSRNEIQIKLTSNVKFATLLGGTLAIIQKVLQINDIYLDIKA

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications