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NCBI: 26-AUG-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA0067 [new locus tag: SA_RS00480 ]
- pan locus tag?: SAUPAN000455000
- symbol: kdpD
- pan gene symbol?: kdpD
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SA0067 [new locus tag: SA_RS00480 ]
- symbol: kdpD
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 74179..76812
- length: 2634
- essential: no DEG
⊟Accession numbers[edit | edit source]
- Gene ID: 1122841 NCBI
- RefSeq: NP_373307 NCBI
- BioCyc: see SA_RS00480
- MicrobesOnline: 102333 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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2581ATTTATTTAGGCTATAGCCCAGGGGTAGGTAAAACGTATGAAATGTTATCAAATGGTATT
GATCAGTATCAAGAAGGTGCAGATATTAAAATTGGTTATATCGAACCCCATCAACGCCCT
GAAACCAATGCACTGGTTCAACAATTGCCTGAAATTTCGACCTCCAGCCGTAAATTTGGC
AGCCACACCTTTCACTATATAGATGTCTCTAAAATCATAGAAGCTAATCCAGATGTGGTC
TTAATTGATGAACTAGCACATACAAACATTTCAAAAGAGCGCCATTTAAAACGTTATAAG
GATATAGAAGAAATTCTATCGCATGGTATCGATGTCTGGACAACACTCAACATCCAACAT
ATCGAGAGTCTAAGCGGACAAATTGCGTTAATGACAGGTATTCAAGTTACAGAACGTGTG
CCCGACCAATTCATTACGTCAGCAGATGCCTTTGAAGTTGTGGATATTTCACCAAATATG
TTGATTCAGCGCCTTAAAGCAGGAAAAGTATATAAAAAAGAACGCTTAGAAACAGCCTTT
TCTAATTTCTTTACGTATGAAAATCTGACAGAGCTGCGTGAACTTACACTCAGAACTGTC
GCAGATATTATGAGTCAAAAAGGACAACAATATAAAACTAAACATACCGACATTACACCG
CATATTGCGGTAGCTATCAGCGGCAGTATTTATAACGAACGGGTCATACGAGAAGCAAGA
CGTGCTGCCTATAAAGAACATGCTAAATTCACAGCTGTGTATATTGATGTCTTTGAGACA
CCGTCAGAAAGCAGAAAACAAGATCATTATGTCCATAAAAATCTAATGCTCGCCAAAGCG
TTAGGTGCAGAAATCAAAGTGTTGTATGCACAAGATATTGCGAAAGCGTTAACCGATTGG
TGTGATCTCGCTTTTGTGACGAAGCTAGTCCTTGGACAGTCAGAACAGCCACGTTGGAAA
GATTACTTTAAACAGTCACTCATTGAACAAATTAATCACGTACCACACCATTTCAAGTTA
GAAATTGTACCGATTCATTATATTCATTCAGACAAACCTACAAATACACCTAAGCAAGCT
CAAAAATCCTCTCGTTTAACTGTAGAGATTATGAAGATGCTTGTAATTCAAACGATCTGT
GTCTTGCTCGGTATATGGGTTTACAACTTAGATAAAAGCGAATCCAGTGCCATTATCTTG
CTGATGTTCTTTATCGGTATTATCGTGCTTTCTATTTGGACCCAATCCTATTTAATCGGA
TTCTTTGCGTCTATCTTAAATGTGTTTGTTTTTAATTATTTCTTTACGGTGCCAAGATTC
ACTTTAGAAATGTATCGCTTTGAATATCCGATTACGTTTGCGACCAGTATTTTTGCTAGT
ATCTTTACGAGTGCCATCTTAAAGAATTTAAAACATCAGCATTCCTTAACAGAACGGCAG
TTATATCGGACCAATATTATGCTGCAATTTAACCAGTCCATTAAAGAATCTTATTCAATT
GAACGCTTATTAAATATTGCTGGTGATCAGATTCATCAGCTACTCAATCAGGATGTCACG
GTATTCTTAATTCAAAGTAAGAAAGTCGCTGCTTCCAACTCATTTGGAAACAGAAGCATT
TCAAGCTCAGATAAGACACATGATGCTGAGACATTGAGCTGGGTCATTGAAAATGAAAGC
CGTGCCGGTAAATTAACCGATACCTTTCCTGGCAGTAAATTTTTGTGTATTCCCATTGGC
ACAAATCCAGTCAAAGGTGTGATTTCTATCCGCTTCACCGACGAAACTTACATCGACACC
TATGACAATTCAATATTAGACTCTATGTTGAACGATATTACCCTGGCAATAGAGAATGTG
GATCTATTAAAACAAACCAGACAATCCATATTGAAAGCTGAACGAGAAGCCACACGTTCA
AACTTCTTGCATTCAATTTCACATGATATTAGAACACCACTGACTTCCATTATGGGCAAC
TTAGATATGCTGAAATACCATAACGAGCATTTAAACGATCAACAACAAGCAGAACTCTTA
ACTGCTTCTTATGGCGAAGCACAATATCTGCATACCTTAGTCACAAATATTTTATCTTTG
ACTAAGTTAGAAAGCTCTGACATTCAAATACAACGCACCCCTTATTTAGTAGAAGAACTT
CTAGAAGAATTTGAAGAAGGCCTCATACGCAGACACCAAGCAAATCATGTCATTATTGAA
AATGAGGATGACGCTTCACTCATTAATATCGACAGTAAATTAATACTGCAAGTGCTATTC
AACCTTATCGATAATGCTTTAAAGCATGCAGAATCACATTCTGAAATAAAACTGCACGTT
CAACATGAAACAAACAAAATAAAATTCGAAATGATAGATTGCGGAAAAGGTATTCCAGAA
GAAGAACGTCAATTGATTTTTAATCCCTATTATTCAGGAGACAACTTTAAAGACAATAAA
AAAGATAGTTTGGGATTAGGGCTCTATTTAGTACAACTCATCTTGAAACAACACAACAGT
GAATTAGAATATCAACCGAATACACCACAAGGCAGTATTTTTTATTTTTATTTGACTGTT
AATCCAATTGAAATGGAGGGAGCCATGGATGAAAACAACATTATTGGTCGTTGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA0067 [new locus tag: SA_RS00480 ]
- symbol: KdpD
- description: hypothetical protein
- length: 877
- theoretical pI: 6.18311
- theoretical MW: 100610
- GRAVY: -0.230673
⊟Function[edit | edit source]
- TIGRFAM: Signal transduction Two-component systems phosphate regulon sensor kinase PhoR (TIGR02966; EC 2.7.3.-; HMM-score: 135.1)Signal transduction Two-component systems TMAO reductase sytem sensor TorS (TIGR02956; EC 2.7.13.3; HMM-score: 123.4)and 6 moreheavy metal sensor kinase (TIGR01386; EC 2.7.13.3; HMM-score: 96.6)proteobacterial dedicated sortase system histidine kinase (TIGR03785; HMM-score: 78.3)Protein fate Protein and peptide secretion and trafficking putative PEP-CTERM system histidine kinase (TIGR02916; EC 2.7.13.3; HMM-score: 46.3)Signal transduction Two-component systems putative PEP-CTERM system histidine kinase (TIGR02916; EC 2.7.13.3; HMM-score: 46.3)Central intermediary metabolism Nitrogen fixation nitrogen fixation negative regulator NifL (TIGR02938; HMM-score: 40.2)Regulatory functions Protein interactions nitrogen fixation negative regulator NifL (TIGR02938; HMM-score: 40.2)
- TheSEED :
- Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)
- PFAM: P-loop_NTPase (CL0023) KdpD; Osmosensitive K+ channel His kinase sensor domain (PF02702; HMM-score: 260.5)and 7 moreno clan defined DUF4118; Domain of unknown function (DUF4118) (PF13493; HMM-score: 73.1)His_Kinase_A (CL0025) HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (PF02518; HMM-score: 63.7)HisKA; His Kinase A (phospho-acceptor) domain (PF00512; HMM-score: 51.8)HATPase_c_5; GHKL domain (PF14501; HMM-score: 21.6)HATPase_c_2; Histidine kinase-like ATPase domain (PF13581; HMM-score: 15.7)no clan defined PHO4; Phosphate transporter family (PF01384; HMM-score: 14.1)EI24; Etoposide-induced protein 2.4 (EI24) (PF07264; HMM-score: 12.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 4
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0.17
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.005532
- TAT(Tat/SPI): 0.000451
- LIPO(Sec/SPII): 0.00134
- predicted transmembrane helices (TMHMM): 4
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFGSHTFHYIDVSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSADAFEVVDISPNMLIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISGSIYNERVIREARRAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDWCDLAFVTKLVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVYNLDKSESSAIILLMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILKNLKHQHSLTERQLYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSISSSDKTHDAETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQSILKAEREATRSNFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDIQIQRTPYLVEELLEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHVQHETNKIKFEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGAMDENNIIGR
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: no data available
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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