PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA0193 [new locus tag: SA_RS01145 ]
• pan locus tag^?: SAUPAN001048000
• symbol: SA0193
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA0193 [new locus tag: SA_RS01145 ]
• symbol: SA0193
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 227874..229052
• length: 1179
• essential: no DEG

⊟Accession numbers

• Gene ID: 1122969 NCBI
• RefSeq: NP_373436 NCBI
• BioCyc: see SA_RS01145
• MicrobesOnline: 102462 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

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  ATGAGGAAAGTTTTAAATATTTTTACAATAGCTTTTAAATCAATATTGAAAAATAAAGGT
  AGAAATATATTTACAATGATAGGTATAATCATCGGTATTTCTTCTGTTATTACGATAATG
  TCTTTGGGAAATGGCTTTAAAAAAACTGCTGCTGATCAATTTTCAGATGCTGGCGCCGGA
  AAACAAGAAGCGTTGATTAGCTTTACTTTTAAAGTTGATGAGAAAATCAAAAAGTATCCT
  TTTAATCAAAGAGATATAGAGTTGGTAAATCAAGTTGATGGCGTACTAGATGCGAAGCTA
  AAGGAAAATAAAGAAGAAGGAATTGAAGCCACAATAACTAATGTCCAGAAAAAAAGTGAC
  ATCTTCATTATAAAAAAACAAAATTTACACTCTTTTAAAGTAGGTAGAGGGTTTGATAAA
  GAGGATAATGAATTACGTAAGAAAATAGTGGTTATAAATGATCAAGTAGCAAAAACTGTA
  TTCAATAATAATGCTATTGGTAAATCGCTATATATTGAGGGACAGGGATTTGAAGTCATA
  GGAATTACGGATAAACTATATTCTGACTCATCTACCGTTATAATGCCTGAAAATACATTC
  AACTACTATATGGGACACTTACATCAAGGTCTGCCTACCTTACAGATAATTATTGAAGAT
  GGTTACAATAAAAAAACTGTAGTTAAAAAAGTAGAATCACTATTAAATAAAAAAGGATCG
  GGCTCTGTTTTAGGTGAGTATACATATACAGACACTGAAGAAATTATCAAAAGTATTGAT
  AAAATTTTTGATAGTATTACTTATTTTGTAGCAGCTGTTGCCGGTATTTCACTTTTTATT
  GCTGGTATTGGAGTTATGAATGTCATGTATATATCTGTAGCTGAAAGAACAGAAGAAATT
  GCGATACGACGTGCATTTGGTGCAAAAAGTCGAGATATTGAACTACAATTTTTAATAGAG
  AGCATTTTAATATGTGTGACAAGTGGTTTTATTGGACTTATTTTAGGTGTTGTGTTTGCA
  ACAATAATTGATGTATTAACACCAGATTATATTAAAAGTGTAGTAAGTTTGAGTTCTGTC
  ATAATTGCGGTTAGTGTGTCGATATTAATTGGACTTCTTTTTGGATGGATACCAGCTCGC
  GCAGCATCTAAGAAAGAGCTCATAGATATTATAAAATAG
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⊟Protein

⊟General

• locus tag: SA0193 [new locus tag: SA_RS01145 ]
• symbol: SA0193
• description: hypothetical protein
• length: 392
• theoretical pI: 9.39443
• theoretical MW: 43335.3
• GRAVY: 0.225765

⊟Function

• TIGRFAM:
  acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 100)
  and 4 more
  Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein, LolC/E family (TIGR02212; HMM-score: 40)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein LolE (TIGR02213; HMM-score: 18.8)
  Cellular processes Cellular processes Cell division putative protein insertion permease FtsX (TIGR00439; HMM-score: 8.4)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking putative protein insertion permease FtsX (TIGR00439; HMM-score: 8.4)
• TheSEED  :
  • ABC transporter, permease protein SERP0016
  MRSA analysis Oli  ABC transporter, permease protein
• PFAM:
  no clan defined MacB_PCD; MacB-like periplasmic core domain (PF12704; HMM-score: 82.2)
  and 3 more
  BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 51.2)
  no clan defined SpecificRecomb; Site-specific recombinase (PF10136; HMM-score: 10.7)
  Tetraspannin (CL0347) DUF4064; Protein of unknown function (DUF4064) (PF13273; HMM-score: 9.9)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 9.99
  • Cellwall Score: 0.01
  • Extracellular Score: 0.01
  • Internal Helices: 4
• LocateP: Multi-transmembrane
  • Prediction by SwissProt Classification: Membrane
  • Pathway Prediction: Sec-(SPI)
  • Intracellular possibility: 0.17
  • Signal peptide possibility: -0.5
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.168094
  • TAT(Tat/SPI): 0.001081
  • LIPO(Sec/SPII): 0.016825
• predicted transmembrane helices (TMHMM): 4

⊟Accession numbers

• GI: 15925903 NCBI
• RefSeq: NP_373436 NCBI
• UniProt: A0A0H3JSK8 UniProt

⊟Protein sequence

• MRKVLNIFTIAFKSILKNKGRNIFTMIGIIIGISSVITIMSLGNGFKKTAADQFSDAGAGKQEALISFTFKVDEKIKKYPFNQRDIELVNQVDGVLDAKLKENKEEGIEATITNVQKKSDIFIIKKQNLHSFKVGRGFDKEDNELRKKIVVINDQVAKTVFNNNAIGKSLYIEGQGFEVIGITDKLYSDSSTVIMPENTFNYYMGHLHQGLPTLQIIIEDGYNKKTVVKKVESLLNKKGSGSVLGEYTYTDTEEIIKSIDKIFDSITYFVAAVAGISLFIAGIGVMNVMYISVAERTEEIAIRRAFGAKSRDIELQFLIESILICVTSGFIGLILGVVFATIIDVLTPDYIKSVVSLSSVIIAVSVSILIGLLFGWIPARAASKKELIDIIK

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SA0191 > SA0192 > SA0193

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications