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NCBI: 26-AUG-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA1042 [new locus tag: SA_RS05925 ]
- pan locus tag?: SAUPAN003479000
- symbol: pyrP
- pan gene symbol?: pyrP
- synonym:
- product: uracil permease
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SA1042 [new locus tag: SA_RS05925 ]
- symbol: pyrP
- product: uracil permease
- replicon: chromosome
- strand: +
- coordinates: 1178528..1179835
- length: 1308
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 1123873 NCBI
- RefSeq: NP_374315 NCBI
- BioCyc: see SA_RS05925
- MicrobesOnline: 103341 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1261ATGCAAAATGATGAAATGTTTGAACGAACAGTAAAACCAGTACTAGATGTAAATGAAAAA
CCACAACCAGCGCAATGGGCATTTTTAAGCTTACAACATTTATTTGCGATGTTTGGCGCA
ACAGTACTAGTACCATTCTTAACAGGACTACCAATATCCGCAGCGTTACTAGCTTCGGGA
ATCGGTACATTACTTTATATCTTAATAACGAAGGCGCAAATACCAGCATACTTGGGATCT
AGCTTTGCATTTATCACACCAATTATCACGGGATTAAGTACGCATAGCTTAGGAGACATG
CTTGTAGCATTATTCATGAGTGGTGTTATGTACGTCATCATCGGAATTCTAATCAAATTA
AGTGGGACAGCATGGTTAATGAAATTATTACCACCAGTTGTTGTTGGACCAGTCATCATG
GTAATTGGTTTAAGCTTAGCGCCTACTGCAGTCAATATGGCAATGTATGAAAATCCTGGA
GATATGAAAGGTTACAATATCAGTTTCTTAATTGTTGCAATGATAACCTTGCTTGTAACA
ATAGTCGTTCAAGGATTTTTTAAAGGATTCCTATCTTTAATTCCAGTACTTGTAGGTATT
ATCGTAGGTTATGTGGTAGCGATTTTTATGGGGATTGTGAAATTTGATGCAATTATGTCA
GCAAAATGGATAGATTTCCCTCATATTTATCTGCCATTTAAAGATTATGTACCTTCATTT
CACTTAGGACTTGTACTTGTAATGATTCCGATTGTGTTTGTAACAGTAAGTGAACATATT
GGGCACCAAATGGTATTGAATAAAATCGTAGGTAGAAACTTCTTTGAAAAGCCAGGACTT
GATAAATCAATCATTGGTGATGGTGTTTCTACAATGTTTGCCAGTATTATTGGTGGACCA
CCAAGTACAACATACGGTGAAAATATCGGTGTATTAGCGATTACAAGAATATACAGTATT
TACGTCATTGGTGGTGCAGCAGTTATAGCAATTGTTTTAGCATTCATTGGTAAGTTCACT
GCATTAATTTCTTCTATACCTACACCAGTTATGGGAGGAGTATCTATATTACTTTTCGGT
ATTATTGCAGCAAGTGGCTTAAGAATGTTAGTTGAAAGCAAAGTAGATTTTGCGAACAAT
CGAAATTTAGTTATAGCTTCTGTAATTTTAGTTGTAGGTATCGGTAATTTAGTATTTAAC
TTAAAAGAAATTGGTATCAACCTTCAAATTGAGGGGATGGCATTAGCTGCACTTTCAGGA
ATTATTTTGAACTTAATCTTACCTAAAGAGAAAAAACAAAACAATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA1042 [new locus tag: SA_RS05925 ]
- symbol: PyrP
- description: uracil permease
- length: 435
- theoretical pI: 9.31816
- theoretical MW: 46609.9
- GRAVY: 0.991724
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Nucleosides, purines and pyrimidines uracil-xanthine permease (TIGR00801; HMM-score: 436.2)and 2 morepyrimidine utilization transport protein G (TIGR03616; HMM-score: 277.1)xanthine permease (TIGR03173; HMM-score: 240.6)
- TheSEED :
- Uracil permease
- Uracil:proton symporter UraA
- PFAM: APC (CL0062) Xan_ur_permease; Permease family (PF00860; HMM-score: 361.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 12
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0.17
- Signal peptide possibility: -0.5
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.009248
- TAT(Tat/SPI): 0.000698
- LIPO(Sec/SPII): 0.003138
- predicted transmembrane helices (TMHMM): 11
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MQNDEMFERTVKPVLDVNEKPQPAQWAFLSLQHLFAMFGATVLVPFLTGLPISAALLASGIGTLLYILITKAQIPAYLGSSFAFITPIITGLSTHSLGDMLVALFMSGVMYVIIGILIKLSGTAWLMKLLPPVVVGPVIMVIGLSLAPTAVNMAMYENPGDMKGYNISFLIVAMITLLVTIVVQGFFKGFLSLIPVLVGIIVGYVVAIFMGIVKFDAIMSAKWIDFPHIYLPFKDYVPSFHLGLVLVMIPIVFVTVSEHIGHQMVLNKIVGRNFFEKPGLDKSIIGDGVSTMFASIIGGPPSTTYGENIGVLAITRIYSIYVIGGAAVIAIVLAFIGKFTALISSIPTPVMGGVSILLFGIIAASGLRMLVESKVDFANNRNLVIASVILVVGIGNLVFNLKEIGINLQIEGMALAALSGIILNLILPKEKKQNN
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: pyrR leader (transcription antitermination) regulon
pyrR leader (RNA) important in Pyrimidine metabolism; RegPrecise binding of the PyrR antitermination protein
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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