From AureoWiki
Jump to navigation Jump to search

NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1373 [new locus tag: SA_RS07770 ]
  • pan locus tag?: SAUPAN004122000
  • symbol: SA1373
  • pan gene symbol?: comGB
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1373 [new locus tag: SA_RS07770 ]
  • symbol: SA1373
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1579157..1580227
  • length: 1071
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAG
    GCCCAACAAATCGATTTACTTTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTG
    TATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATAAAAATAAGCAATTAGGTACC
    ACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
    TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGAC
    GTTCTAGAAGAAACCGTAAATTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTA
    AAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTATTGCTATGATTATTATATTA
    AACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
    TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATG
    CTCATAATAGTATCTATGTTGGCTATTATTATGAAATTAATTTATAACAATTTAAATATG
    CTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATATCAGGCTATTTCCAATTATTT
    AAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
    TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAA
    TACTTATTAACTTATTCAGAAATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAA
    TGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTGAAAAGAGAGGGAAGCTAGAA
    GTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
    CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATT
    TATTTAGTAATTATGTTACCAATGTTTCAAATGATGCAAAGTATAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1071

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1373 [new locus tag: SA_RS07770 ]
  • symbol: SA1373
  • description: hypothetical protein
  • length: 356
  • theoretical pI: 10.0622
  • theoretical MW: 41447.6
  • GRAVY: 0.401124

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type II secretion system protein F (TIGR02120; HMM-score: 95.4)
  • TheSEED  :
    • Late competence protein ComGB, access of DNA to ComEA
    DNA Metabolism DNA uptake, competence Gram Positive Competence  Late competence protein ComGB, access of DNA to ComEA
    and 1 more
    DNA Metabolism DNA uptake, competence Late competence  Late competence protein ComGB, access of DNA to ComEA
  • PFAM:
    no clan defined T2SSF; Type II secretion system (T2SS), protein F (PF00482; HMM-score: 81.2)
    and 2 more
    E1-E2_ATPase; E1-E2 ATPase (PF00122; HMM-score: 9.3)
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 6.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00519
    • TAT(Tat/SPI): 0.000223
    • LIPO(Sec/SPII): 0.001581
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIGYSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLSSFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQSIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIKQTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: SigH* regulon
    SigH*(sigma factor)controlling competence and phage integrase genes;  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Kazuya Morikawa, Yumiko Inose, Hideyuki Okamura, Atsushi Maruyama, Hideo Hayashi, Kunio Takeyasu, Toshiko Ohta
    A new staphylococcal sigma factor in the conserved gene cassette: functional significance and implication for the evolutionary processes.
    Genes Cells: 2003, 8(8);699-712
    [PubMed:12875655] [WorldCat.org] [DOI] (P p)

⊟Relevant publications[edit | edit source]

Retrieved from "http://aureowiki.med.uni-greifswald.de/index.php?title=SA1373&oldid=74574"