PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary

• organism: Staphylococcus aureus COL
• locus tag: SACOL0904 [new locus tag: SACOL_RS04640 ]
• pan locus tag^?: SAUPAN002866000
• symbol: SACOL0904
• pan gene symbol^?: —
• synonym:
• product: pathogenicity island protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SACOL0904 [new locus tag: SACOL_RS04640 ]
• symbol: SACOL0904
• product: pathogenicity island protein
• replicon: chromosome
• strand: +
• coordinates: 914733..915260
• length: 528
• essential: unknown

⊟Accession numbers

• Gene ID: 3237772 NCBI
• RefSeq: YP_185775 NCBI
• BioCyc: see SACOL_RS04640
• MicrobesOnline: 912375 MicrobesOnline

⊟Phenotype

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⊟DNA sequence

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  ATGAAACTGCTTAAAACGAAGAATTGTTTATATTATCGTAATGGCGACAATAAACTATCT
  GAGTATCAACTATTAACGCAATTTAACCCAGCATTTATTAATAAAAAAATTAAGATGTGT
  GAATTCCAAATTGAAAGTATGTACCATATGAGTGCGTCGACCACAACATGTGATGAAATA
  ATGGGGGTCGTGTCTGTCTCATATCCGATTGAAAAATTAGTTATCAAAATTATTGAAACA
  AAAGCAGGGTTACAAAACTATAAAAATAGATCTATAAATAATATGGCGTTGTTGAAAAAG
  GTACTAAATCATTATACAGAAAAAGAGCAGAAGCAAGTTGTAAAATATATGCGTTCAAAT
  GGACGATATAAGCCCTACAACGTCATTGAACGCTTACAAGTTGATTTGTATCAAGCAAGT
  ATTAAACAACGTTCAGAACGTCAAAAACAAAGAAATACAGCAATTGAAAACAGTAAGATT
  GCACGAGTAAATGCATATCACCAATCTTCATATGTAAAAGTGGTGTAA
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  528
  

⊟Protein

⊟General

• locus tag: SACOL0904 [new locus tag: SACOL_RS04640 ]
• symbol: SACOL0904
• description: pathogenicity island protein
• length: 175
• theoretical pI: 10.237
• theoretical MW: 20591.8
• GRAVY: -0.621143

⊟Function

• TIGRFAM:
• TheSEED  :
  • Hypothetical SAV0798 homolog in superantigen-encoding pathogenicity islands SaPI
  Phages, Prophages, Transposable elements, Plasmids Pathogenicity islands Staphylococcal pathogenicity islands SaPI  Hypothetical SAV0798 homolog in superantigen-encoding pathogenicity islands SaPI
• PFAM:
  no clan defined PSDC; Phophatidylserine decarboxylase (PF12588; HMM-score: 16.8)
  DUF1307; Protein of unknown function (DUF1307) (PF06998; HMM-score: 14.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.014732
  • TAT(Tat/SPI): 0.000206
  • LIPO(Sec/SPII): 0.0016
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 57651594 NCBI
• RefSeq: YP_185775 NCBI
• UniProt: A0A0H2WYC2 UniProt

⊟Protein sequence

• MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQIESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKAGLQNYKNRSINNMALLKKVLNHYTEKEQKQVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKIARVNAYHQSSYVKVV

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SACOL0904 > SACOL0905 > SACOL0906

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications