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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1059 [new locus tag: SACOL_RS05400 ]
  • pan locus tag?: SAUPAN003257000
  • symbol: SACOL1059
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1059 [new locus tag: SACOL_RS05400 ]
  • symbol: SACOL1059
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1065904..1066914
  • length: 1011
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGACTTCATTAAAAGAGAGAGATTATTTTTTTGACAACGCAAGAGCAATTTTAATATTA
    TTAGTCGTATTTGGACATATGTTACAACCCTACACTAGTGGCGATAAATATTTATCAGCA
    TTATACCTAGTTATTTATAGTTTCCATATGCCAACATTTTTGTTTATATCTGGTTATTTC
    GCGAAAAATATTGATAAACCATACTATTTAGAAAAAATTTCAAAACGTTTGATAGTACCT
    TATATGATATTTTTTGCATTCTTTTCAATTTATTATTTCTTAACAGGTAAAAGTGACGAA
    TTACAACTTGATCCTTTTAACCCAGTATTTGCGTTATGGTTTTTGATCACGCTATTTTTC
    TTTCATGTCATTTTAGTAATAGTTAGAAGATTTAATCCATATAAAGTGCTATCAGTTTCA
    ATTATTATATCTATTGGAGCAGGTTTTTCAGATAACATCGATAGCTACTTAAGCATTTCA
    AGGACAATCGTATTTTTCCCAATATTTTATCTAGGTTACATTTTCACCAAAAAACATACG
    GCTATTTTTAAAAATAAAAAACTAATACCAGTATCTATCATTACCTTTATTTTGTTTTTT
    ATCGTTTACGTGATTCATCCTATCAATGCAGATTGGTTATTGGGAAGTTCACCATATACT
    TCACTTGAAAATGAAGGACAGAGTATATTCAGTCCTTTTAAACGACTTATATTATATGGA
    ATTATATTAATCGCAATGACTGCGTTTCTAAATTTAATGTCAACAAAGAAAAAATTATAT
    ACTTATATTGGTAGTCGTACGCTATACGTATATTTATTACATGGTTTAATTATTGGCATT
    GTTAGAGGATTTGAATGGTACCCATTCGATAATCCTATATCATTAATGACTTATCTTTAT
    TTAATAAGTATATCTGTAATCATCGTATATGTATTATCTACAAACTTTGTTTGTAAATGG
    ACAAATCCAATAATTAATTTACAAAGACCATCACAGTTTAAAGATTCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1011

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL1059 [new locus tag: SACOL_RS05400 ]
  • symbol: SACOL1059
  • description: hypothetical protein
  • length: 336
  • theoretical pI: 9.78139
  • theoretical MW: 39255.4
  • GRAVY: 0.629167

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • membrane protein, putative
  • PFAM:
    Acyl_transf_3 (CL0316) Acyl_transf_3; Acyltransferase family (PF01757; HMM-score: 76.1)
    and 1 more
    no clan defined MWFE; NADH-ubiquinone oxidoreductase MWFE subunit (PF15879; HMM-score: 9.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.026925
    • TAT(Tat/SPI): 0.001821
    • LIPO(Sec/SPII): 0.008489
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTSLKERDYFFDNARAILILLVVFGHMLQPYTSGDKYLSALYLVIYSFHMPTFLFISGYFAKNIDKPYYLEKISKRLIVPYMIFFAFFSIYYFLTGKSDELQLDPFNPVFALWFLITLFFFHVILVIVRRFNPYKVLSVSIIISIGAGFSDNIDSYLSISRTIVFFPIFYLGYIFTKKHTAIFKNKKLIPVSIITFILFFIVYVIHPINADWLLGSSPYTSLENEGQSIFSPFKRLILYGIILIAMTAFLNLMSTKKKLYTYIGSRTLYVYLLHGLIIGIVRGFEWYPFDNPISLMTYLYLISISVIIVYVLSTNFVCKWTNPIINLQRPSQFKDS

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: Integral membrane [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS One: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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