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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1703 [new locus tag: SACOL_RS08685 ]
  • pan locus tag?: SAUPAN004254000
  • symbol: SACOL1703
  • pan gene symbol?: mreD
  • synonym:
  • product: rod shape-determining protein MreD

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1703 [new locus tag: SACOL_RS08685 ]
  • symbol: SACOL1703
  • product: rod shape-determining protein MreD
  • replicon: chromosome
  • strand: -
  • coordinates: 1733628..1734158
  • length: 531
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCGTACACTGTATTATTTTTTGATAGGTATTTTACTATTTTATATAGATACTGCAATT
    GGGCTTCTTATTCCAATGCACATAGGTAAGTTTGAACTTGTATTTGTACCACACCTTACA
    TTTATGTATATTTTAATGATGGTAGTGTATCGTGGCTTTGGCGTATCATTATTGCTCAGC
    ATATTTTTAGGCGTAATGACTGATGTATACTTTGGTAGTATTTATGGAGTGTACTTATTT
    GGCTATATATTGTTTTTAGCACTTATAGATCGATTCTTTAAAATTTTTTACAAAGATCAT
    TCGATGTTATTCATTATTATATTAGCCAGCACCTTATTATTAGAAGTCTATGTGGCATTA
    ATATACGGTATGTTAGGATTCATTCAATTTGATATTATTCATTTTGTAGTCTTTAGATTA
    TTGCCAACATTAATTATGAATTTTGTACTGTTGATTATGCTTTATCCGTTGATTATAAAG
    TTCCTTAAAAAAACAAACAATGACATTGACATGAAACGTCGTCAATGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    531

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL1703 [new locus tag: SACOL_RS08685 ]
  • symbol: SACOL1703
  • description: rod shape-determining protein MreD
  • length: 176
  • theoretical pI: 9.52813
  • theoretical MW: 20826.5
  • GRAVY: 1.21989

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan rod shape-determining protein MreD (TIGR03426; HMM-score: 82.4)
  • TheSEED  :
    • Rod shape-determining protein MreD
    Cell Division and Cell Cycle Cell Division and Cell Cycle - no subcategory Bacterial Cytoskeleton  Rod shape-determining protein MreD
  • PFAM:
    Gx_transp (CL0315) MreD; rod shape-determining protein MreD (PF04093; HMM-score: 138.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007233
    • TAT(Tat/SPI): 0.000087
    • LIPO(Sec/SPII): 0.036548
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MRTLYYFLIGILLFYIDTAIGLLIPMHIGKFELVFVPHLTFMYILMMVVYRGFGVSLLLSIFLGVMTDVYFGSIYGVYLFGYILFLALIDRFFKIFYKDHSMLFIIILASTLLLEVYVALIYGMLGFIQFDIIHFVVFRLLPTLIMNFVLLIMLYPLIIKFLKKTNNDIDMKRRQW

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: Integral membrane [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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