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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2009 [new locus tag: SACOL_RS10490 ]
  • pan locus tag?: SAUPAN005197000
  • symbol: SACOL2009
  • pan gene symbol?: —
  • synonym:
  • product: tetracenomycin polyketide synthesis O-methyltransferase TcmP

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2009 [new locus tag: SACOL_RS10490 ]
  • symbol: SACOL2009
  • product: tetracenomycin polyketide synthesis O-methyltransferase TcmP
  • replicon: chromosome
  • strand: -
  • coordinates: 2069080..2069925
  • length: 846
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAAGCAACTGGTTGGAATTCCCGAATCAATGTTAATTCCTTTGATAGCTCGAGCAAAA
    GAGTACGAAAACGAAAAACCAATAATAAAAGACGCACTATCAAAAAAAATATTTGATGGT
    TTAGATGATATGTACAAAAATGTTACATGTGATGACATGTCTCAAATTGGAATTAGTATA
    CGTACTGTGATAATAGATTGTGTTACTAAGAGGCTTATCAAGGATAATAAAGATTTAATC
    GTGGTCAATATAGGTTGTGGCTTAGATACAAGGTTTCAAAGATTTAATAAAGAAAAAATA
    TCATGGATAGATTTAGATGTACCAGAATCAATAGAAATACGAAAAACATTTTTTAAAGAA
    AGTAATAGTTATAAGATGATATCTAAATCTATGCTAGATTACAGTTGGATTGATGATGTC
    AAAAATTATAAATTTTTTAATAGTAAGTCAGATATATTGTTTATTATTGAAGGTGTATTG
    ATGTATTTTGATGAGAGTGTAATGACTCAATTATTGGACACTATTATCAAAAAGATGGGA
    GATCATAATTTGACATTTGCGATTGAATTTTGCTCAAAAACAATTGCGAATAATACAAAG
    AGACATCAATCGGTATCAAAGTTATCCTCACAACCTGTTTTTAAATATGGTTACAATGAT
    TTAAAAAAATTGAATGAAATTTTACCAAATACAATAAGAGTAATACATGAATATAATTAT
    TTTGACTATTATAAGAATCGATGGGGCTTATTTGGATATTGTAGATTTATACCTTATTTA
    AAAAAAAGGTTAAACAATAAAATAGTACTTATGAAATATAAAGTTCCAAAGAGACAGAGA
    CATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    846

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2009 [new locus tag: SACOL_RS10490 ]
  • symbol: SACOL2009
  • description: tetracenomycin polyketide synthesis O-methyltransferase TcmP
  • length: 281
  • theoretical pI: 9.74266
  • theoretical MW: 33222.7
  • GRAVY: -0.339502

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function Enzymes of unknown specificity methyltransferase, TIGR00027 family (TIGR00027; EC 2.1.1.-; HMM-score: 41.6)
  • TheSEED  :
    • FIG01107971: hypothetical protein
  • PFAM:
    NADP_Rossmann (CL0063) LCM; Leucine carboxyl methyltransferase (PF04072; HMM-score: 53.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.105032
    • TAT(Tat/SPI): 0.001307
    • LIPO(Sec/SPII): 0.004996
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKQLVGIPESMLIPLIARAKEYENEKPIIKDALSKKIFDGLDDMYKNVTCDDMSQIGISIRTVIIDCVTKRLIKDNKDLIVVNIGCGLDTRFQRFNKEKISWIDLDVPESIEIRKTFFKESNSYKMISKSMLDYSWIDDVKNYKFFNSKSDILFIIEGVLMYFDESVMTQLLDTIIKKMGDHNLTFAIEFCSKTIANNTKRHQSVSKLSSQPVFKYGYNDLKKLNEILPNTIRVIHEYNYFDYYKNRWGLFGYCRFIPYLKKRLNNKIVLMKYKVPKRQRH

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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