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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2440 [new locus tag: SACOL_RS12805 ]
  • pan locus tag?: SAUPAN005985000
  • symbol: SACOL2440
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2440 [new locus tag: SACOL_RS12805 ]
  • symbol: SACOL2440
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2497523..2498329
  • length: 807
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAGATAGGGACAATCGCCGATTTACATATTGATCGTCATAATAAAAAAACATCCGAA
    GATTACTTAGAGGCATTGGTTGAAATAGTTAAGTATAAGAAATTGGATATATTGTTGATT
    GCGGGGGATATCTCAAATCATTATCAATTGACGCACCAATTTATAACGCAATTGACAAAA
    CAATTAGATATACCTGTGAAATTTGTACCTGGAAACCATGATTTATGGGAAGTTGAAAGT
    ATGACTACGCAAGACATTTGGAATAATTATAAGAGTATGTCACAGTGCTTGGTAGGAAAA
    CCATTTATAGTAAATGAAGAATGGGCAATCATAGGACATACTGGCTGGTATGATTATAGC
    TTTGCAGCACAACGATTTTCATTAGATGAGTTACAAAAAGGAAAACATTATGGTGCGACT
    TGGCAAGATAAAGAACGAATATCTTGGGGCATATCAGATCAAAATTTATCTAAAATAGCG
    GCTGAACAAGTGAAGAAAGATATATTAGAAGTAGGAAATAGACGAGTGATTTTAGTCACA
    CATGTTGTGACGCACCCTGATTTCATTGTTCCTATGCCGCATCGTATATTCGATTTTTAT
    AATGCATTTATTGGGACAAGTGATTTCAATCCTTTGTATGCGATGTTCGATATACCATAT
    AGTATTATGGGCCATGTTCATTTTCGTAAAAGTGTGATAGATGATGGCAGATGTTATCTC
    TGTCCGTGTCTAGGCTATCCAAGACAATGGCGTTCAGAAGATATTTACCAGGAAATAAAT
    GAGACGATACAAATAATAGAAATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    807

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2440 [new locus tag: SACOL_RS12805 ]
  • symbol: SACOL2440
  • description: hypothetical protein
  • length: 268
  • theoretical pI: 6.22779
  • theoretical MW: 31298.6
  • GRAVY: -0.28209

⊟Function[edit | edit source]

  • TIGRFAM:
    putative phosphoesterase (TIGR03729; HMM-score: 284.4)
    and 5 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair exonuclease SbcCD, D subunit (TIGR00619; HMM-score: 25.2)
    Unknown function Enzymes of unknown specificity phosphodiesterase, MJ0936 family (TIGR00040; EC 3.1.-.-; HMM-score: 21.8)
    TIGR04168 family protein (TIGR04168; HMM-score: 21.1)
    metallophosphoesterase, DNA ligase-associated (TIGR04123; HMM-score: 19.9)
    Unknown function Enzymes of unknown specificity putative phosphoesterase (TIGR00024; EC 3.1.-.-; HMM-score: 15.7)
  • TheSEED  :
    • Predicted phosphohydrolases
  • PFAM:
    Calcineurin (CL0163) Metallophos; Calcineurin-like phosphoesterase (PF00149; HMM-score: 49.4)
    Metallophos_2; Calcineurin-like phosphoesterase superfamily domain (PF12850; HMM-score: 40.2)
    and 1 more
    Metallophos_3; Metallophosphoesterase, calcineurin superfamily (PF14582; HMM-score: 13.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001331
    • TAT(Tat/SPI): 0.000078
    • LIPO(Sec/SPII): 0.000354
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDISNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKSMSQCLVGKPFIVNEEWAIIGHTGWYDYSFAAQRFSLDELQKGKHYGATWQDKERISWGISDQNLSKIAAEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDIPYSIMGHVHFRKSVIDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: Cytoplasmic [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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