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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2727 [new locus tag: SACOL_RS14260 ]
  • pan locus tag?: SAUPAN006473000
  • symbol: SACOL2727
  • pan gene symbol?:
  • synonym:
  • product: integrase/recombinase core subunit

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2727 [new locus tag: SACOL_RS14260 ]
  • symbol: SACOL2727
  • product: integrase/recombinase core subunit
  • replicon: chromosome
  • strand: +
  • coordinates: 2799000..2799536
  • length: 537
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    GTGCTAAACTCAATATGTATTTCCTACCAAAGAAAACATAAGGAGTTTGGACATCTTGAA
    GGAGATACTATTGTTGGTCGTCGTCATGGTAGTGCAATCATTACTTTGGTAGAAAGAGTA
    TCCAAGATGATTATCACCTTACGACCCTTAGGTCGTAAGGCAACTGATATAGAAAACGCT
    CTACACTCAATGTTTTCATCTTTACCTTCTCATATATTTAAATCAATTACTTTTGATTGT
    GGTAAGGAGTTCTCAAACTGGAAAACATTATGTAACTGTCACGATATATCTATATTTTTT
    GCTGATCCAGGCACGCCATCACAGCGAGGTTTAAATGAACATTCTAACGGAATACTTAGA
    CGCAGTGGATTAGATAAAGAACTAGATTTCAATTTAGTAACAGACGATCATATCATCAGT
    GTTGCTCAAAAAATCAATCATCGTCCTAGAAAATCTTTAGGTTATAGAACACCATTGGAA
    GTATTTATGAGTTTCATCGAAGATGATAAACTTGTCCAGCTTAATTTGACAATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    537

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL2727 [new locus tag: SACOL_RS14260 ]
  • symbol: SACOL2727
  • description: integrase/recombinase core subunit
  • length: 178
  • theoretical pI: 8.6638
  • theoretical MW: 20250.2
  • GRAVY: -0.257865

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Integrase/recombinase, core domain family
  • PFAM:
    RNase_H (CL0219) rve; Integrase core domain (PF00665; HMM-score: 42.1)
    and 1 more
    rve_3; Integrase core domain (PF13683; HMM-score: 27.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004791
    • TAT(Tat/SPI): 0.000577
    • LIPO(Sec/SPII): 0.001005
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLNSICISYQRKHKEFGHLEGDTIVGRRHGSAIITLVERVSKMIITLRPLGRKATDIENALHSMFSSLPSHIFKSITFDCGKEFSNWKTLCNCHDISIFFADPGTPSQRGLNEHSNGILRRSGLDKELDFNLVTDDHIISVAQKINHRPRKSLGYRTPLEVFMSFIEDDKLVQLNLTI

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]