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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40
NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL_RS00370 [old locus tag: SACOL0072 ]
- pan locus tag?: SAUPAN000387000
- symbol: SACOL_RS00370
- pan gene symbol?: —
- synonym:
- product: LysR family transcriptional regulator
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL_RS00370 [old locus tag: SACOL0072 ]
- symbol: SACOL_RS00370
- product: LysR family transcriptional regulator
- replicon: chromosome
- strand: +
- coordinates: 80406..81266
- length: 861
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841TTGAACTTAAACATTTTAAAATCATTTTTAGTAACTAGTGAAACAAAGAACCTTACTAAA
GCATCAGAGTTACTTAACTATTCACAGTCAACTGTATCTACACATATTGAAAAATTAGAA
AGGCAATTAGATGTTAAATTATTTTATAGAAAAAAATATGGTATGGAACTAACGGAAGAA
GGCTTAGCATACGTTAAATACGCTAAAGTGATTTTAGATAGTAATAGCGAATACGAGAGA
GAAATAAAAGGACTTTACAATAAGAAGGTAAATATAAGTATTAACATGCAAGAAAGTCAG
TATTTGTATCGCTACTATAATAAGATTAGTGAATGGTTAGCTGAACACCCATATGTAAAC
TTGAAGTTTAAATCCGCACATTCTAATTTCTATATTAAAGAAGAAATTGCTAATTTCAAA
TCGGATATTAGCCTTATCACAGACGAAAAGATTATTAATAGTAACTTAACTGCTATTCCT
ATAACTGAAGAACGTTTAATATTTGTTACTAACAAAGAGATGAAAGATTTCAAATTAAAC
GATATTCAAAACCATACATTACTTGTTACTGAAAAAGGGTGTAGTTACAGAGAACAGTTA
GAAATGATTTTATATAAATATAGCTTTTCAACAAAACAAATGATTGAATTTCTAGGAATT
GAGTCATTAAAAAAACACTTGAAAAATTCAGGTGGGATTGCGCTATTGCCGGAATTTATT
GTTGCAGATGAATTAGAAAATAAAAGTTTGTTTCAAATAGACGTAGATGTCGATATTCCG
AATTTAGAAACAACATTGATAATTAATCCTGAATCGAATAAGCAAGTACTTGAATCTTTT
GTAAAAGATGTTTTTTTATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL_RS00370 [old locus tag: SACOL0072 ]
- symbol: SACOL_RS00370
- description: LysR family transcriptional regulator
- length: 286
- theoretical pI: 5.76749
- theoretical MW: 33410.2
- GRAVY: -0.331119
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions aminoethylphosphonate catabolism associated LysR family transcriptional regulator (TIGR03339; HMM-score: 82.8)and 7 moreEnergy metabolism Other pca operon transcription factor PcaQ (TIGR02424; HMM-score: 51.3)Regulatory functions DNA interactions pca operon transcription factor PcaQ (TIGR02424; HMM-score: 51.3)putative choline sulfate-utilization transcription factor (TIGR03418; HMM-score: 40.9)Regulatory functions DNA interactions D-serine deaminase transcriptional activator (TIGR02036; HMM-score: 31.6)Cellular processes Toxin production and resistance transcriptional regulator, ArgP family (TIGR03298; HMM-score: 24.3)DNA metabolism DNA replication, recombination, and repair transcriptional regulator, ArgP family (TIGR03298; HMM-score: 24.3)Regulatory functions DNA interactions transcriptional regulator, ArgP family (TIGR03298; HMM-score: 24.3)
- TheSEED: see SACOL0072
- PFAM: HTH (CL0123) HTH_1; Bacterial regulatory helix-turn-helix protein, lysR family (PF00126; HMM-score: 60.8)PBP (CL0177) LysR_substrate; LysR substrate binding domain (PF03466; HMM-score: 59.4)and 5 moreHTH (CL0123) HTH_5; Bacterial regulatory protein, arsR family (PF01022; HMM-score: 16.7)HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 14.7)PspA (CL0235) Snf7; Snf7 (PF03357; HMM-score: 13.6)HTH (CL0123) HTH_20; Helix-turn-helix domain (PF12840; HMM-score: 12.7)OB (CL0021) DUF3127; Domain of unknown function (DUF3127) (PF11325; HMM-score: 12.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006889
- TAT(Tat/SPI): 0.000433
- LIPO(Sec/SPII): 0.000793
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNLNILKSFLVTSETKNLTKASELLNYSQSTVSTHIEKLERQLDVKLFYRKKYGMELTEEGLAYVKYAKVILDSNSEYEREIKGLYNKKVNISINMQESQYLYRYYNKISEWLAEHPYVNLKFKSAHSNFYIKEEIANFKSDISLITDEKIINSNLTAIPITEERLIFVTNKEMKDFKLNDIQNHTLLVTEKGCSYREQLEMILYKYSFSTKQMIEFLGIESLKKHLKNSGGIALLPEFIVADELENKSLFQIDVDVDIPNLETTLIINPESNKQVLESFVKDVFL
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.