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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS00960 [old locus tag: SACOL0188 ]
  • pan locus tag?: SAUPAN001060000
  • symbol: SACOL_RS00960
  • pan gene symbol?: ggt
  • synonym:
  • product: gamma-glutamyltranspeptidase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS00960 [old locus tag: SACOL0188 ]
  • symbol: SACOL_RS00960
  • product: gamma-glutamyltranspeptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 220341..222347
  • length: 2007
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_002951 (220341..222347) NCBI
  • BioCyc: SACOL_RS00960 BioCyc
  • MicrobesOnline: see SACOL0188

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    ATGGTCATTAACTTAAATGACAAACAGACAAAAACATCTAAAGAAGGGTTAATTTCCGTA
    TCACATCCTCTTGCGGCTAAAATTGGTAAGGATGTATTAGATCAAGGTGGCAACGCCATG
    GATGCAGTGATTGCAATTCAACTGGCATTGAATGTGGTAGAACCATTTGCATCAGGTATT
    GGTGGTGGCGGGTATTTGCTATATTATGAGCAAAGTACTGGCAGTATAACTGCGTTTGAT
    GCACGTGAGACAGCACCTGAACATGTAGACAAACAATTTTATCTAGATGATTCAGGCGAA
    TATAAATCATTTTTTGATATGACTACACATGGTAAAACTGTCGCTGTGCCAGCAATTCCA
    AAGCTGTTTGATTATATTCACAAGCGTTATGCTAAATTGTCATTGGAAGATTTAATTAAT
    CCTGCAATTGAACTAGCCATTGAAGGTCATGCAGCCAATTGGGCTACTGAAAAATATTCG
    CGCCAGCAACACGCACGATTGACAAAGTATCATGAAACGGCACAAGTATTTACGCATGAA
    AATCAATATTGGCGTGAAGGTGATTGGATTGTACAACCCGAATTAGGTAAGACATTTCAA
    ATATTAAGAGAACAAGGGTTTAATGCATTTTATAAAGGTGACATTGCGAAACAATTAGTC
    AATGTTGTCAAAGCATGTGGTGGGACAATCACTTTAGAGGATCTAGCCAAATATGACATT
    CAGATTAAAGCGCCAATCAGTGCAACATTTAAAGACTATGACATTTATTCAATGGGACCA
    TCTAGTTCTGGCGGTATCACGGTAATTCAAATATTGAAGTTATTAGAACATGTCGATTTA
    CCATCTATGGGTCCAAGATCTGTTGATTACTTGCATCATTTGATACAAGCGATGCATTTA
    GCATATAGTGATCGTGCGCAATACTTGGCGGATGATAATTTTCATGAGGTGCCTGTACAG
    TCATTAATTGATGATGATTATTTAAAAGCACGCAGTACGCTCATTGATAGCAATAAAGCA
    AATATTGATATAGAGCATGGTGTTGTGTCTGATTGCATTAGTCATACAGATGTTGAAGAA
    AATCATACCGAAACAACTCATTTTTGTGTGATTGATAAGGAAGGTAATATTGCTTCATTT
    ACGACATCAATTGGTATGATTTATGGTTCAGGTATCACGATTCCAGGCTACGGTGTGTTA
    TTGAATACGACAATGGATGGCTTTGATGTAGTAGATGGTGGTATTAACGAAATTGCACCA
    TATAAACGACCACTAAGTAACATGGCTCCAACGATTGTGATGTATCACGGGAAGCCAATA
    TTAACAGTAGGTGCACCTGGTGCCATAAGTATCATTGCTAGTGTTGCGCAAACATTAATC
    AATGTATTAGTGTTTGGCATGGATATTCAGCAGGCTATAGATGAACCTAGAATTTATAGT
    AGCCATCCTAATCGCATTGAATGGGAGCCTCAATTTTCACAATCTACAATATTAGCATTG
    ATTGCACATGGACATGCAATGGAACATAAACCAGATGCTTATATTGGAGATGTACATGGA
    CTACAGGTTGACCCAACAACGTATGAAGCTTCGGGTGGAAGTGATGATACTAGAGAAGGC
    ACCGTAATGGGTGGCGAGGTGTTAGTGATTAGAAAACAGCCATTACCATATCGGCAAATG
    TATGATAGTGACGGCTTTCGTCTATATTTCAATGATGTGCAGTTACCTTTATTGGCAGAT
    CAAGTGCGATGGATGCATGACAAATATTGGGTTGATGAAAGTGTTGTTAGAATCATTTTC
    CCTGAAGTTAGTGCACATATTGAAGATTTAAGAAGTTATGAAAACGCAGGAGAAAATTAT
    ATAGATATTGCCTGGTTAGCACGGAAATATGCTTATCAAGTAACATTGAAGGATGACGGT
    TTATACTTAACTGATGATACATATACTTCAGTGAAACGGAACACAAATGCATACTATAGA
    TATGATCGAGATAGTATCACAAGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2007

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS00960 [old locus tag: SACOL0188 ]
  • symbol: SACOL_RS00960
  • description: gamma-glutamyltranspeptidase
  • length: 668
  • theoretical pI: 4.91254
  • theoretical MW: 74693.6
  • GRAVY: -0.257784

Function[edit | edit source]

  • reaction:
    EC 2.3.2.2?  ExPASy
    Gamma-glutamyltransferase A (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid
  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs gamma-glutamyltransferase (TIGR00066; EC 2.3.2.2; HMM-score: 505.5)
  • TheSEED: see SACOL0188
  • PFAM:
    NTN (CL0052) G_glu_transpept; Gamma-glutamyltranspeptidase (PF01019; HMM-score: 551.9)
    and 1 more
    Asparaginase_2; Asparaginase (PF01112; HMM-score: 16.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.1
    • Cytoplasmic Membrane Score: 0.14
    • Cellwall Score: 0.15
    • Extracellular Score: 9.6
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007882
    • TAT(Tat/SPI): 0.000284
    • LIPO(Sec/SPII): 0.000915
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MVINLNDKQTKTSKEGLISVSHPLAAKIGKDVLDQGGNAMDAVIAIQLALNVVEPFASGIGGGGYLLYYEQSTGSITAFDARETAPEHVDKQFYLDDSGEYKSFFDMTTHGKTVAVPAIPKLFDYIHKRYAKLSLEDLINPAIELAIEGHAANWATEKYSRQQHARLTKYHETAQVFTHENQYWREGDWIVQPELGKTFQILREQGFNAFYKGDIAKQLVNVVKACGGTITLEDLAKYDIQIKAPISATFKDYDIYSMGPSSSGGITVIQILKLLEHVDLPSMGPRSVDYLHHLIQAMHLAYSDRAQYLADDNFHEVPVQSLIDDDYLKARSTLIDSNKANIDIEHGVVSDCISHTDVEENHTETTHFCVIDKEGNIASFTTSIGMIYGSGITIPGYGVLLNTTMDGFDVVDGGINEIAPYKRPLSNMAPTIVMYHGKPILTVGAPGAISIIASVAQTLINVLVFGMDIQQAIDEPRIYSSHPNRIEWEPQFSQSTILALIAHGHAMEHKPDAYIGDVHGLQVDPTTYEASGGSDDTREGTVMGGEVLVIRKQPLPYRQMYDSDGFRLYFNDVQLPLLADQVRWMHDKYWVDESVVRIIFPEVSAHIEDLRSYENAGENYIDIAWLARKYAYQVTLKDDGLYLTDDTYTSVKRNTNAYYRYDRDSITR

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: see SACOL0188
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]