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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS01365 [old locus tag: SACOL0269 ]
  • pan locus tag?: SAUPAN001173000
  • symbol: SACOL_RS01365
  • pan gene symbol?:
  • synonym:
  • product: DUF5080 domain-containing protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS01365 [old locus tag: SACOL0269 ]
  • symbol: SACOL_RS01365
  • product: DUF5080 domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 307973..308560
  • length: 588
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_002951 (307973..308560) NCBI
  • BioCyc: SACOL_RS01365 BioCyc
  • MicrobesOnline: see SACOL0269

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
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    481
    541
    ATGATAATTTTTATTTTAATAACAATATTTGCTATTTATTATATAGCTATGATTGCTAGT
    TTGTTTAAAAGTGAAGGTTTTTCAATAATAGGTTTAATATTAGATGTTGTTATAATGGGG
    ACATTGATTTTTTACTATTTTATAGGCGCTCGCTTTGTTGATCATGATTTAAGCAACTTT
    TTAATGTTTATGGATACTGGATCATATATTTTTATGTACTTTGCAATTAAGTGTTTATGG
    GTGAAACCTAAGGTAGTAAATTATTTGATTGCAAAAGAATTGGGTGAATCTAAAGAGGTC
    ATTGAAGAGCAGGAATTAGATTTACAGACATCAAAGATAAGAGGTATCTACTTTTTCATT
    ATTTCAGTAGTGATGTTAATTATCACTAAATTAAGAATGCAACCTGAGTTACAGGCAGAT
    GCTATATCGATGAATCCTGTATTTATTTTTGTTGGTGTTATAATCATTTTAATTTGGCTA
    GTACTGGATATATATCGCAAGAAAAAATACGGTATATTCTTATTCAAGACGATAGTGCCA
    CTAGTTGTTACGACTTGGATTATTATAGCTACAATTATACTTTCGTAA
    60
    120
    180
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    360
    420
    480
    540
    588

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS01365 [old locus tag: SACOL0269 ]
  • symbol: SACOL_RS01365
  • description: DUF5080 domain-containing protein
  • length: 195
  • theoretical pI: 8.36398
  • theoretical MW: 22572.4
  • GRAVY: 1.10974

Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 9.3)
  • TheSEED: see SACOL0269
  • PFAM:
    no clan defined DUF5080; Domain of unknown function (DUF5080) (PF16883; HMM-score: 290.7)
    and 1 more
    DUF4199; Protein of unknown function (DUF4199) (PF13858; HMM-score: 10.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005658
    • TAT(Tat/SPI): 0.000121
    • LIPO(Sec/SPII): 0.007168
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MIIFILITIFAIYYIAMIASLFKSEGFSIIGLILDVVIMGTLIFYYFIGARFVDHDLSNFLMFMDTGSYIFMYFAIKCLWVKPKVVNYLIAKELGESKEVIEEQELDLQTSKIRGIYFFIISVVMLIITKLRMQPELQADAISMNPVFIFVGVIIILIWLVLDIYRKKKYGIFLFKTIVPLVVTTWIIIATIILS

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: see SACOL0269
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]