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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL_RS03170 [old locus tag: SACOL0613 ]
- pan locus tag?: SAUPAN002343000
- symbol: SACOL_RS03170
- pan gene symbol?: folE2
- synonym:
- product: GTP cyclohydrolase I FolE2
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL_RS03170 [old locus tag: SACOL0613 ]
- symbol: SACOL_RS03170
- product: GTP cyclohydrolase I FolE2
- replicon: chromosome
- strand: -
- coordinates: 647315..648193
- length: 879
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841ATGACTGAATTTGATTTATCGACACGAGAAGGTCGTTGGAAACACTTTGGTTCCGTAGAT
CCTATTGAAGGCACGAAACCTACTACTAAGAACGAAATGACAGATTTACAAAGTACACAT
AAAGATTTTTTATTTGAAATAGAAGAAGTTGGTATTAAAAACTTAGTGTACCCTGTACTT
GTTGACCAGTATCAAACAGCTGGCACATTTAGTTTTTCAACAAGTTTAACAAAAGACGAA
AAAGGTATTAATATGAGCCGTATAATCGAAAGTGTTGAAAAGCACTATGATAATGGTATT
GAACTTGAATTTAATACACTTTATCAGGTGTTACGCACTTTACAAACGAATATGAAACAA
AATGCGGCAGGCGTTGATGTTTCTGGGAAATGGTTCTTTGATCGCTATAGTCCAACCACA
AATATTAAAGCAGTTGGTAATGCCGATGTCACTTATGGATTAGCAATTGACGGTGATAAA
GTTACACGTAAAGAACTTACTATTGAAGCAACTGTCACAACGCTATGCCCTTGTTCAAAA
GAAATAAGTGAGTATTCAGCGCACAACCAACGTGGTGTTGTCACTGTTAAAACATATATT
AATAAAGATCAAGACATAGTTGATGACTATAAAAATAAAATTTTAGATGCAATGGAAGCT
AATGCAAGTTCAATTCTATACCCTATTTTAAAACGTCCTGATGAAAAACGTGTGACAGAG
CGTGCATATGAAAATCCACGTTTTGTCGAAGACTTAATTCGTTTAATTGCCGCGGACTTA
GTTGAATTTGATTGGTTAGACGGTTTCGATATCGAATGTCGTAATGAAGAGTCTATCCAT
CAACATGATGCTTTCGCTAAATTAAAGTATCGCAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL_RS03170 [old locus tag: SACOL0613 ]
- symbol: SACOL_RS03170
- description: GTP cyclohydrolase I FolE2
- length: 292
- theoretical pI: 4.85913
- theoretical MW: 33481.4
- GRAVY: -0.542466
⊟Function[edit | edit source]
- reaction: EC 3.5.4.16? ExPASyGTP cyclohydrolase I GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Other GTP cyclohydrolase (TIGR00294; EC 3.5.4.-; HMM-score: 169.5)
- TheSEED: see SACOL0613
- PFAM: THBO-biosyn (CL0334) GCHY-1; Type I GTP cyclohydrolase folE2 (PF02649; HMM-score: 235.2)and 1 moreHTH (CL0123) PadR; Transcriptional regulator PadR-like family (PF03551; HMM-score: 14.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.005134
- TAT(Tat/SPI): 0.00032
- LIPO(Sec/SPII): 0.001326
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKVTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQDIVDDYKNKILDAMEANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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