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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS04280 [old locus tag: SACOL0832 ]
  • pan locus tag?: SAUPAN002692000
  • symbol: SACOL_RS04280
  • pan gene symbol?: whiA
  • synonym:
  • product: sporulation regulator WhiA

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS04280 [old locus tag: SACOL0832 ]
  • symbol: SACOL_RS04280
  • product: sporulation regulator WhiA
  • replicon: chromosome
  • strand: +
  • coordinates: 858434..859378
  • length: 945
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_002951 (858434..859378) NCBI
  • BioCyc: G1G4B-901 BioCyc
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAGCTTTGCATCAGAAATGAAAAATGAATTAACTAGAATAGACGTCGATGAAATGAAT
    GCAAAAGCAGAGCTCAGTGCACTGATTCGAATGAATGGTGCACTTAGTCTTTCAAATCAA
    CAATTTGTTATAAATGTTCAAACGGAAAATGCAACAACGGCAAGACGTATTTATTCGTTG
    ATTAAACGTGTCTTTAATGTGGAAGTTGAAATATTAGTCCGTAAAAAAATGAAACTTAAA
    AAAAATAATATTTATATTTGTCGTACAAAGATGAAAGCGAAAGAAATTCTTGATGAATTA
    GGAATTTTAAAAGACGGCATTTTTACGCATGAAATTGATCATTCAATGATTCAAGATGAC
    GAAATGAGACGCAGTTACTTGAGAGGAGCTTTTCTGGCAGGTGGCTCAGTGAATAACCCT
    GAAACATCTTCGTACCATTTGGAAATTTTTTCTCAAAATGAGAGTCATGCAGAAGGCTTA
    ACGAAACTAATGAATAGTTATGAGTTGAATGCCAAACATTTAGAGCGAAAAAAAGGAAGT
    ATTACGTATTTAAAAGAAGCGGAAAAGATTTCGGATTTTCTTAGTTTGATAGGTGGCTAT
    CAAGCGTTATTAAAATTTGAAGACGTACGTATTGTAAGAGATATGCGTAATTCTGTTAAC
    CGACTCGTTAATTGTGAAACGGCCAATCTAAATAAAACAGTTAGTGCTGCGATGAAACAA
    GTTGAGAGCATTAAATTGATTGATAAAGAAATTGGTATTGAAAATTTACCAGACAGGTTG
    AGAGAGATTGCTAGAATTCGAGTAGAACATCAAGAAATTTCGTTGAAAGAGCTTGGAGAA
    ATGGTATCAACTGGTCCAATTTCAAAATCAGGTGTAAATCACCGATTAAGAAAACTGAAT
    GATTTAGCCGATAAGATTAGAAATGGTGAACAAATAGAATTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    945

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS04280 [old locus tag: SACOL0832 ]
  • symbol: SACOL_RS04280
  • description: sporulation regulator WhiA
  • length: 314
  • theoretical pI: 9.22195
  • theoretical MW: 35868.1
  • GRAVY: -0.422611

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Cell division DNA-binding protein WhiA (TIGR00647; HMM-score: 447.1)
  • TheSEED:
  • PFAM:
    Homing_endonuc (CL0324) LAGLIDADG_WhiA; WhiA LAGLIDADG-like domain (PF14527; HMM-score: 125.3)
    HTH (CL0123) HTH_WhiA; WhiA C-terminal HTH domain (PF02650; HMM-score: 121.2)
    Homing_endonuc (CL0324) WhiA_N; WhiA N-terminal LAGLIDADG-like domain (PF10298; HMM-score: 118.2)
    and 2 more
    LAGLIDADG_3; LAGLIDADG-like domain (PF14528; HMM-score: 16.7)
    no clan defined DUF3486; Protein of unknown function (DUF3486) (PF11985; HMM-score: 14.5)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003018
    • TAT(Tat/SPI): 0.000921
    • LIPO(Sec/SPII): 0.000446
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI: 445928696 NCBI
  • RefSeq: WP_000006551 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL

Experimental data[edit | edit source]

  • experimentally validated: no data available

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]