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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS05740 [old locus tag: SACOL1124 ]
  • pan locus tag?: SAUPAN003342000
  • symbol: SACOL_RS05740
  • pan gene symbol?: ctaA
  • synonym:
  • product: heme A synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS05740 [old locus tag: SACOL1124 ]
  • symbol: SACOL_RS05740
  • product: heme A synthase
  • replicon: chromosome
  • strand: -
  • coordinates: 1136065..1137135
  • length: 1071
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (1136065..1137135) NCBI
  • BioCyc: SACOL_RS05740 BioCyc
  • MicrobesOnline: see SACOL1124

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGTCGTCCACATACAATACTTGTAAAATTAAATCATATTTCCTGCGTTGGATCCCATCT
    TTTCATATCCTACAATCAGGTCTATTTATAGTATCATCTCAAAGCCGGCTATTAATTCTA
    ATTCTCAGTGATGCGTTTTTTTATGATGGGGTGTATAAATTGTTTGGCAAAAAGAATTTA
    AAATGGTTAGGTGTCGTAGCAACGTTAATGATGACATTTGTACAACTTGGTGGAGCCTTA
    GTTACCAAAACCGGATCAGCTGATGGTTGTGGTTCTTCTTGGCCACTATGTCATGGTGCG
    TTGATTCCAGAATTCTTTCCTATTGATACGATTATTGAGTTAAGTCATAGAGCCGTTTCA
    GCTTTGTCTTTATTAATGGTCTTATGGTTAGTTATCACTGCATGGAAACATATAGGCTAT
    ATTAAAGAAATTAAACCTTTATCAATCATTAGTGTTGGATTCTTATTATTGCAAGCATTA
    ATCGGAGCTGCTGCTGTTATTTGGCAACAAAACGATTACGTTTTAGCATTGCACTTTGGT
    ATATCATTAATCAGTTTCTCATCTGTATTTTTAATAACATTGATTATTTTCTCTATAGAT
    CAAAAATATGAAGCTGACGAATTATATATCAAAAAGCCATTAAGACGTTTAACATGGTTA
    ATGGCAATCATCATTTATTGTGGTGTTTATACTGGTGCACTAGTGAGACATGCGGATGCA
    AGTTTAGCATATGGTGGTTGGCCATTGCCATTCCACGATCTTGTACCACATTCAGAACAA
    GATTGGGTTCAACTCACGCATCGTATCATGGCTTTTATAGTGTTTACGATTATTATGATT
    ACTTATATTCACGCTGTTAAAAATTATCCAAATAACCGTACTGTTCATTATGGTTATACA
    GCTGCATTTATACTTGTTATATTACAAGTTATCACAGGTGCATTATCTATTATGACAAAT
    GTTAACCTGATAATCGCACTTTTCCATGCATTATTTATCACTTATTTATTTGGTATGACA
    ACATACTTTATCATGCTAATGTTACGATCAGTAAGAAGTGACAAGCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1071

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS05740 [old locus tag: SACOL1124 ]
  • symbol: SACOL_RS05740
  • description: heme A synthase
  • length: 356
  • theoretical pI: 9.42349
  • theoretical MW: 40222.6
  • GRAVY: 0.720506

⊟Function[edit | edit source]

  • reaction:
    EC 1.3.-.-?  ExPASy
  • TIGRFAM:
    methanobactin biosynthesis cassette protein MbnC (TIGR04160; HMM-score: 12.7)
    surface glycoprotein signal peptide (TIGR04207; HMM-score: 11.3)
  • TheSEED: see SACOL1124
  • PFAM:
    2heme_cytochrom (CL0328) COX15-CtaA; Cytochrome oxidase assembly protein (PF02628; HMM-score: 115.7)
    and 1 more
    no clan defined DUF4231; Protein of unknown function (DUF4231) (PF14015; HMM-score: 9.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.015111
    • TAT(Tat/SPI): 0.000671
    • LIPO(Sec/SPII): 0.009383
  • predicted transmembrane helices (TMHMM): 8

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSSTYNTCKIKSYFLRWIPSFHILQSGLFIVSSQSRLLILILSDAFFYDGVYKLFGKKNLKWLGVVATLMMTFVQLGGALVTKTGSADGCGSSWPLCHGALIPEFFPIDTIIELSHRAVSALSLLMVLWLVITAWKHIGYIKEIKPLSIISVGFLLLQALIGAAAVIWQQNDYVLALHFGISLISFSSVFLITLIIFSIDQKYEADELYIKKPLRRLTWLMAIIIYCGVYTGALVRHADASLAYGGWPLPFHDLVPHSEQDWVQLTHRIMAFIVFTIIMITYIHAVKNYPNNRTVHYGYTAAFILVILQVITGALSIMTNVNLIIALFHALFITYLFGMTTYFIMLMLRSVRSDKQ

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: see SACOL1124
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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