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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL_RS10635 [old locus tag: SACOL2037 ]
- pan locus tag?: SAUPAN005296000
- symbol: SACOL_RS10635
- pan gene symbol?: —
- synonym:
- product: DNA mismatch repair protein MutS
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL_RS10635 [old locus tag: SACOL2037 ]
- symbol: SACOL_RS10635
- product: DNA mismatch repair protein MutS
- replicon: chromosome
- strand: +
- coordinates: 2096287..2097897
- length: 1611
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1561ATGAGCACAAATCAAACATTTTTAATATTTGTTATAGCAATTATTCTACTTACATCTGTA
ATAGGAATTGTTGGACGATACATGAGTCGTCAACGTCTATTAAAATCTATGGAAACATTA
TGGCAAACGATTTCTCCATTAGAAGCTTTTATCAGACCGAACTCACATTTCGACTATGAG
TATAAGCTCTACAAGGAAAAATTTGAATCACATTCATTAGTTGATGATAAAACTTGGTCC
GACTTAAATATGAATGCAATCTTTCATAAGATGAATTATAATTTAACAGCTATTGGTGAA
ATGAAGCTATATGCCTGTTTACGTGGAATGCTTTCAATTACGAACAAATCATTACTTAGT
TTATTTAATGATAATGCTGAATTTAGAAAAAACGTAACATATCATTTAGCTTTGATTGGT
AAAACTGTTTATCCAACATTTCCAGACCAAATCACACCGGTAAAACGTCAAAATATATTG
TTTCTATGCCCGTTTTTACCAGTTATCTCATTTGCAGTTATATTTATTAATTCACAAGTT
GGTATTTTATTATTTCTTATGAGTTGCCTATTTAATATCATTTTATCAGCAACTTTAAAG
CGTACATATGAGGATGACTTAAAATCTATCTTTTATGCATCCAATGTTTTAAAACAAGGC
TATACTATCTCAAAAATTAAACATGCTCCACAACCTGAAGTCAATTTTAAGCAATTTAGA
ACAGCACGTCATTTAACGAGTGTTTTAGCTGAAGTTAATGATGAAGATATCGGAGCTATG
GTAATTAAACTAGTTAAACTTATTTTCATGCTTGATTATGTTTTATTTCATTCAATTCAA
AAAAGCTATACAACACATATGAATGAGCTTAAAAATTGTTTCGATTACATAGCTGAATTA
GATAATCATTATGCATTAGCAATGTATCGTAGAACGCTAGAATGTTATACTGAACCACAA
ATTGATGATTCAAATGATGGCATAGTATTCTCTGAGTTAACACATCCACTCATAGCAGAT
GCAGTAGCCAATGATTTCTCACTATCACAAAATATACTGTTAACTGGGTCTAATGCTTCG
GGTAAATCAACATTTATGAAATCCATAGCAATAAACATTATTCTTGCATCGGCTATACAA
ACAGTTACCGCAAGCAAATTTGTATATCAACCTGGAATTGTGTTCACGTCAATGGCAAAT
GCCGATGATGTGTTATCAGGCGATAGTTATTTTATGGCTGAATTAAAATCTATTAAGCGT
ATTGTTGAAATTCCAGATAATCAAAAAATATACTGCTTTATAGATGAAATTTTTAAAGGT
ACCAACACAACTGAACGAATTGCCGCTTCAGAATCAGTACTATCATTTTTACATGAAAAA
TCTAACTTTAGAGTTATTGCAGCAACACATGATATTGAGTTAGCTGAACTCTTAAAACAA
CGTTATGAAAATTACCATTTCAATGAGGTAATAGAAAATAATAACATACATTTTGATTAC
AAAATTAAGCCTGGCAAAGCAAATACACGTAATGCCATCGAATTATTAAAAATCACTTCA
TTTCCAGCAAAAATATATGAACGAGCAAAAGATAATGTCCCGAAAATTTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL_RS10635 [old locus tag: SACOL2037 ]
- symbol: SACOL_RS10635
- description: DNA mismatch repair protein MutS
- length: 536
- theoretical pI: 7.6459
- theoretical MW: 61321.6
- GRAVY: 0.0182836
⊟Function[edit | edit source]
- TIGRFAM: DNA metabolism DNA replication, recombination, and repair DNA mismatch repair protein MutS (TIGR01070; HMM-score: 120.7)and 4 moreDNA metabolism Other MutS2 family protein (TIGR01069; HMM-score: 59.9)P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 13.3)Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCb (TIGR03925; HMM-score: 12.7)Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 11.8)
- TheSEED: see SACOL2037
- PFAM: P-loop_NTPase (CL0023) MutS_V; MutS domain V (PF00488; HMM-score: 104.3)and 10 moreAAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 20.4)AAA_14; AAA domain (PF13173; HMM-score: 20)AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 19.4)G-alpha; G-protein alpha subunit (PF00503; HMM-score: 16.8)FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 15.4)ABC_tran; ABC transporter (PF00005; HMM-score: 14.7)T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 13.1)AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 12.2)no clan defined Baculo_11_kDa; Baculovirus 11 kDa family (PF06143; HMM-score: 7.1)Sigma_reg_N; Sigma factor regulator N-terminal (PF13800; HMM-score: 6.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.07
- Cytoplasmic Membrane Score: 9.55
- Cellwall Score: 0.18
- Extracellular Score: 0.21
- Internal Helices: 3
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.087395
- TAT(Tat/SPI): 0.001793
- LIPO(Sec/SPII): 0.025101
- predicted transmembrane helices (TMHMM): 2
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSTNQTFLIFVIAIILLTSVIGIVGRYMSRQRLLKSMETLWQTISPLEAFIRPNSHFDYEYKLYKEKFESHSLVDDKTWSDLNMNAIFHKMNYNLTAIGEMKLYACLRGMLSITNKSLLSLFNDNAEFRKNVTYHLALIGKTVYPTFPDQITPVKRQNILFLCPFLPVISFAVIFINSQVGILLFLMSCLFNIILSATLKRTYEDDLKSIFYASNVLKQGYTISKIKHAPQPEVNFKQFRTARHLTSVLAEVNDEDIGAMVIKLVKLIFMLDYVLFHSIQKSYTTHMNELKNCFDYIAELDNHYALAMYRRTLECYTEPQIDDSNDGIVFSELTHPLIADAVANDFSLSQNILLTGSNASGKSTFMKSIAINIILASAIQTVTASKFVYQPGIVFTSMANADDVLSGDSYFMAELKSIKRIVEIPDNQKIYCFIDEIFKGTNTTERIAASESVLSFLHEKSNFRVIAATHDIELAELLKQRYENYHFNEVIENNNIHFDYKIKPGKANTRNAIELLKITSFPAKIYERAKDNVPKI
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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