Jump to navigation
Jump to search
NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL_RS11120 [old locus tag: SACOL2125 ]
- pan locus tag?: SAUPAN005429000
- symbol: SACOL_RS11120
- pan gene symbol?: hmrA
- synonym:
- product: aminobenzoyl-glutamate utilization protein B
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL_RS11120 [old locus tag: SACOL2125 ]
- symbol: SACOL_RS11120
- product: aminobenzoyl-glutamate utilization protein B
- replicon: chromosome
- strand: -
- coordinates: 2186403..2187587
- length: 1185
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141ATGAGTGAAAAACAACAAATTCTCGATTATATAGAAACAAATAAATATAGTTATATCGAA
ATCAGTCATAGAATTCATGAACGTCCTGAACTTGGTAATGAAGAAATATTTGCGTCTCGA
ACTTTAATAGATCGTTTGAAAGAGCATGATTTTGAAATTGAAACCGAGATTGCTGGGCAT
GCAACTGGGTTTATAGCGACATATGATTCAGGACTTGACGGGCCAGCTATAGGTTTTTTA
GCAGAATACGATGCTTTGCCAGGATTGGGTCATGCTTGTGGTCATAATATCATTGGAACT
GCAAGTGTTCTTGGTGCAATTGGTTTGAAGCAAGTGATTGACCAAATTGGTGGTAAAGTA
GTCGTTCTTGGATGTCCAGCTGAAGAAGGTGGGGAAAATGGTAGCGCTAAAGCTTCTTAT
GTCAAGGCTGGTGTGATTGATCAAATAGACATTGCCTTAATGATTCATCCGGGAAATGAA
ACTTATAAAACGATTGATACTTTGGCAGTGGATGTTTTAGATGTTAAATTTTACGGAAAA
AGTGCTCATGCCTCTGAAAATGCAGATGAAGCGTTAAATGCATTAGACGCTATGATTAGT
TATTTTAATGGTGTAGCACAACTACGACAACATATTAAAAAAGATCAACGTGTGCATGGT
GTGATTTTAGATGGCGGGAAAGCAGCTAATATTATTCCAGACTATACACATGCTCGTTTT
TATACTAGAGCAATGACGCGTAAAGAATTGGATATATTAACAGAAAAAGTAAATCAAATC
GCACGTGGAGCTGCGATACAGACTGGTTGTGATTATGAATTTGGTCGAATTCAAAACGGT
GTGAATGAATTCATTAAAACGCCGAAATTAGATGATTTATTTGCTAAATATGCTGAAGAA
GTTGGTGAAGCAGTTATTGATGATGATTTTGGTTATGGCTCTACGGATACAGGGAACGTA
AGTCATGTTGTGCCAACAATACATCCTCATATTAAAATAGGATCACGTAATTTAGTAGGA
CATACGCATAGATTTAGAGAAGCGGCTGCGAGTGTACATGGTGATGAAGCATTAATTAAA
GGCGCTAAAATAATGGCGTTGATGGGGTTAGAGTTAATTACAAATCAAGACGTTTATCAA
GACATTATTGAAGAGCATGCGCATTTGAAAGGGAATGGGAAGTAA60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
960
1020
1080
1140
1185
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL_RS11120 [old locus tag: SACOL2125 ]
- symbol: SACOL_RS11120
- description: aminobenzoyl-glutamate utilization protein B
- length: 394
- theoretical pI: 5.27078
- theoretical MW: 42958.1
- GRAVY: -0.219289
⊟Function[edit | edit source]
- TIGRFAM: Protein fate Degradation of proteins, peptides, and glycopeptides amidohydrolase (TIGR01891; HMM-score: 202.1)and 5 moreProtein fate Degradation of proteins, peptides, and glycopeptides peptidase, ArgE/DapE family (TIGR01910; EC 3.4.-.-; HMM-score: 44.7)Amino acid biosynthesis Glutamate family acetylornithine deacetylase (ArgE) (TIGR01892; EC 3.5.1.16; HMM-score: 18.7)Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01900; EC 3.5.1.18; HMM-score: 14.9)Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01246; EC 3.5.1.18; HMM-score: 13.7)N-acyl-L-amino-acid amidohydrolase (TIGR01880; EC 3.5.1.14; HMM-score: 10.7)
- TheSEED: see SACOL2125
- PFAM: no clan defined M20_dimer; Peptidase dimerisation domain (PF07687; HMM-score: 31.6)Peptidase_MH (CL0035) Peptidase_M20; Peptidase family M20/M25/M40 (PF01546; HMM-score: 29.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002298
- TAT(Tat/SPI): 0.000106
- LIPO(Sec/SPII): 0.0002
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSEKQQILDYIETNKYSYIEISHRIHERPELGNEEIFASRTLIDRLKEHDFEIETEIAGHATGFIATYDSGLDGPAIGFLAEYDALPGLGHACGHNIIGTASVLGAIGLKQVIDQIGGKVVVLGCPAEEGGENGSAKASYVKAGVIDQIDIALMIHPGNETYKTIDTLAVDVLDVKFYGKSAHASENADEALNALDAMISYFNGVAQLRQHIKKDQRVHGVILDGGKAANIIPDYTHARFYTRAMTRKELDILTEKVNQIARGAAIQTGCDYEFGRIQNGVNEFIKTPKLDDLFAKYAEEVGEAVIDDDFGYGSTDTGNVSHVVPTIHPHIKIGSRNLVGHTHRFREAAASVHGDEALIKGAKIMALMGLELITNQDVYQDIIEEHAHLKGNGK
⊟Experimental data[edit | edit source]
- experimentally validated: see SACOL2125
- protein localization: see SACOL2125
- quantitative data / protein copy number per cell: see SACOL2125
- interaction partners:
SACOL_RS05645 dihydrolipoyl dehydrogenase [1] (data from MRSA252) SACOL_RS08930 pyruvate kinase [1] (data from MRSA252) SACOL_RS11695 30S ribosomal protein S5 [1] (data from MRSA252) SACOL_RS11750 30S ribosomal protein S3 [1] (data from MRSA252)
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: CodY see SACOL2125
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ 1.0 1.1 1.2 1.3 Artem Cherkasov, Michael Hsing, Roya Zoraghi, Leonard J Foster, Raymond H See, Nikolay Stoynov, Jihong Jiang, Sukhbir Kaur, Tian Lian, Linda Jackson, Huansheng Gong, Rick Swayze, Emily Amandoron, Farhad Hormozdiari, Phuong Dao, Cenk Sahinalp, Osvaldo Santos-Filho, Peter Axerio-Cilies, Kendall Byler, William R McMaster, Robert C Brunham, B Brett Finlay, Neil E Reiner
Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.
J Proteome Res: 2011, 10(3);1139-50
[PubMed:21166474] [WorldCat.org] [DOI] (I p)