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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL_RS12760 [old locus tag: SACOL2431 ]
- pan locus tag?: SAUPAN005972000
- symbol: SACOL_RS12760
- pan gene symbol?: —
- synonym:
- product: ABC transporter ATP-binding protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL_RS12760 [old locus tag: SACOL2431 ]
- symbol: SACOL_RS12760
- product: ABC transporter ATP-binding protein
- replicon: chromosome
- strand: -
- coordinates: 2489554..2491317
- length: 1764
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1741ATGAACAATCAGACAAATTGGATAAAGATACTCAGCGGATTTGCTTCTGATAGTAAATGG
AAAATTATGTTATCAATTTTGTTGTCTATCATCAGTGTCTTTTCTGGATTAGTTCCTTAT
TGGGCAGTATTTAAAATTATTTTAATGATGATTAACAATACATATACGATTAATTCGATT
ATGGTTTATATCTTTATTGCTTTAATCGCTTATATTTCACAAGTGTGTTGTTTTGGAGCG
TCAACGATGCTATCACATATTACGGCATATGAAATTTTATCTGAAATTCGTAAAAAATTA
GCTCAAAAATTAATGCGTCTCCCTTTAGGCGTAGTGGAATCTAAGAAAATAGGTGAATTA
AAAAATATATTTGTCGATAAGGTTGAAACAATAGAATTACCTTTAGCACATATGATTCCT
GAAGTTATAGGAAACTTACTTTTGTCAGCTGCTATCTTTTTATACATAATGCTCATTGAT
TGGCGTATGGCTAGTGCCTTATTAGTAACGATACCAATTTCAATTTTCGCTTTTAAAAAA
GTTATGTCTGGATTTAATGAGACATATGCTGAACAAATGAAATCGAATAATTATATGAAT
AGCGCGATTGTAGAGTTTATCGAAGGCATTGAAGTGATTAAAACATTTAATCAATCTCAA
AGTTCATATAAAAAATATAAAGATGCAGTAGATAATTATAAGATTCACACTTTGAATTGG
TTTAAAAATACATGGGGGTATATGAATTTAGGAGCTAGTGTATTACCTTCAACATTTTTA
GGGATTTTACCGGTCGGCATGTATTTGATATCTATCAACCAATTAAACTATGCGGAATTT
TTCCTATGCATCGTATTATCTTTAGGTGTAGTAGCACCGATTAAGAATTTTACTAATTAT
GTAAATCATTTAAAGTCTATACAATACGCATTAACTGAAGTGAATCAAATATTAAGTCTA
GAAGAGTTAGTATTGTCAACAAAATTTAAGAAGCCTCAACATTATGAAATTGCTTTTAAT
AATGTTGGATTTTCATATAACAAAGATAAGGACGATCTGGTCTTTAAGCATTTATCATTT
ACAGTACCAGAAAATAATTTCACAGCTATCGTCGGGGCATCTGGTAGCGGTAAGTCAACC
ATTGCCAAGCTTATATCACGATACTGGGATGTGACTTCAGGTGAAATTACGATTGGCGGT
ATAAATATAAAAGATATTGAATCGAAACAACTTAACGATTTAGTTGGTTTTGTTGGACAA
GATAACTTTTTATTAAATCTTACTTTTAAAGAAAATATTAAACTTGGCAATCCAGAAGCT
ACGGATGAGGCAGTTGAAAAAGCTGCCAAGTTAGCACAATGTCATGAATTTATTGAAAAG
TTGCCAGATGGATATGATACGAATGTTGGTACAGTGGGAGATAAATTGTCTGGTGGTGAA
AAACAACGAGTCACTATTGCAAGAATGATATTAAAAGATGCGCCTATCATTGTATTAGAT
GAAGCGACTGTTTACGTTGATCCAGACAACGAACAAAAAATTCAAGAAGCATTAAATGTG
TTGACGCAGGATAAAACATTGATTGTTATTGCACATCGGTTATCTACGATTCAACATGCA
GATCAAATTATTGTTTTAGGTAAACAACAAATTTTAGAAAAAGGGTCACATCACTTATTG
CTAAAATTAAACGGTAATTATAAGAAAATGTGGGATACGCACATGCATACAAAAGATTGG
GGAATCAATACTGGACATAATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL_RS12760 [old locus tag: SACOL2431 ]
- symbol: SACOL_RS12760
- description: ABC transporter ATP-binding protein
- length: 587
- theoretical pI: 7.71696
- theoretical MW: 66115.6
- GRAVY: 0.133731
⊟Function[edit | edit source]
- ⊞TIGRFAM: Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 340.2)Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 340.2)ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 308.8)thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 291.9)Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 279.7)and 72 more
- TheSEED: see SACOL2431
- ⊞PFAM: P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 104.7)ABC_membrane (CL0241) ABC_membrane; ABC transporter transmembrane region (PF00664; HMM-score: 90.1)and 21 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVFKIILMMINNTYTINSIMVYIFIALIAYISQVCCFGASTMLSHITAYEILSEIRKKLAQKLMRLPLGVVESKKIGELKNIFVDKVETIELPLAHMIPEVIGNLLLSAAIFLYIMLIDWRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQSQSSYKKYKDAVDNYKIHTLNWFKNTWGYMNLGASVLPSTFLGILPVGMYLISINQLNYAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQHYEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFTAIVGASGSGKSTIAKLISRYWDVTSGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAKLAQCHEFIEKLPDGYDTNVGTVGDKLSGGEKQRVTIARMILKDAPIIVLDEATVYVDPDNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLLKLNGNYKKMWDTHMHTKDWGINTGHN
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization:
- quantitative data / protein copy number per cell:
- ⊟interaction partners:
SACOL_RS08865 aldehyde dehydrogenase [1] (data from MRSA252)
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊞Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊞Other Information[edit | edit source]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Artem Cherkasov, Michael Hsing, Roya Zoraghi, Leonard J Foster, Raymond H See, Nikolay Stoynov, Jihong Jiang, Sukhbir Kaur, Tian Lian, Linda Jackson, Huansheng Gong, Rick Swayze, Emily Amandoron, Farhad Hormozdiari, Phuong Dao, Cenk Sahinalp, Osvaldo Santos-Filho, Peter Axerio-Cilies, Kendall Byler, William R McMaster, Robert C Brunham, B Brett Finlay, Neil E Reiner
Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.
J Proteome Res: 2011, 10(3);1139-50
[PubMed:21166474] [WorldCat.org] [DOI] (I p)