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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS12770 [old locus tag: SACOL2433 ]
  • pan locus tag?: SAUPAN005976000
  • symbol: SACOL_RS12770
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS12770 [old locus tag: SACOL2433 ]
  • symbol: SACOL_RS12770
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2491945..2492052
  • length: 108
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_002951 (2491945..2492052) NCBI
  • BioCyc: SACOL_RS12770 BioCyc
  • MicrobesOnline: see SACOL2433

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTT
    TTTGCACATTGGTTACGAACGCGCAACAATAAAAAAGGTGACAAATAA
    60
    108

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS12770 [old locus tag: SACOL2433 ]
  • symbol: SACOL_RS12770
  • description: hypothetical protein
  • length: 35
  • theoretical pI: 11.06
  • theoretical MW: 4011.76
  • GRAVY: 0.197143

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED:
  • PFAM:
    Holin-III (CL0564) Phage_holin_3_3; LydA holin phage, holin superfamily III (PF16083; HMM-score: 13.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide LIPO(Sec/SPII) length 15 aa
    • SP(Sec/SPI): 0.039777
    • TAT(Tat/SPI): 0.002981
    • LIPO(Sec/SPII): 0.710081
    • Cleavage Site: CS pos: 15-16. ISG-CL. Pr: 0.6895
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]