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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS13155 [old locus tag: SACOL2511 ]
  • pan locus tag?: SAUPAN006098000
  • symbol: SACOL_RS13155
  • pan gene symbol?: fnbA
  • synonym:
  • product: fibronectin-binding protein A

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS13155 [old locus tag: SACOL2511 ]
  • symbol: SACOL_RS13155
  • product: fibronectin-binding protein A
  • replicon: chromosome
  • strand: -
  • coordinates: 2569440..2572496
  • length: 3057
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2569440..2572496) NCBI
  • BioCyc: SACOL_RS13155 BioCyc
  • MicrobesOnline: see SACOL2511

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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    841
    901
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    1021
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    1321
    1381
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    3001
    GTGAAAAACAATCTTAGGTACGGCATTAGAAAACATAAATTGGGAGCAGCATCAGTATTC
    TTAGGAACAATGATCGTTGTTGGGATGGGACAAGACAAAGAAGCTGCAGCATCAGAACAA
    AAGACAACTACAGTAGAAGAAAATGGGAATTCAGCTACTGATAATAAAACAAGTGAAACA
    CAAACAACTGCAACTAACGTTAATCATATAGAAGAAACTCAATCATATAACGCAACAGTA
    ACAGAACAACCGTCAAACGCAACACAAGTAACAACTGAAGAAGCACCAAAAGCAGTACAA
    GCACCACAAACTGCACAACCAGCAAATATAGAAACAGTTAAAGAAGAGGTAGTTAAGGAA
    GAAGCGAAACCTCAAGTTAAGGAAACAACACAATCTCAAGACAATAGCGGAGATCAAAGA
    CAAGTAGATTTAACACCTAAAAAGGCTACACAAAATCAAGTCGCAGAAACACAAGTTGAA
    GTGGCACAGCCAAGAACGGCATCAGAAAGTAAGCCACGTGTGACAAGATCAGCAGATGTA
    GCGGAAGCTAAGGAAGCTAGTAACGCGAAAGTGGAAACGGGTACAGATGTAACAAGTAAA
    GTTACAGTAGAAATTGGTTCTATTGAGGGGCATAACAATACAAATAAAGTAGAACCTCAT
    GCAGGACAACGAGCGGTACTAAAATATAAGTTGAAATTTGAGAATGGTTTACATCAAGGT
    GACTACTTTGACTTTACTTTATCAAATAATGTAAATACGCATGGCGTATCAACTGCTAGA
    AAAGTACCAGAAATTAAAAATGGTTCAGTCGTAATGGCGACAGGTGAAGTTTTAGAAGGT
    GGAAAGATTAGATATACATTTACAAATGATATTGAAGATAAGGTTGATGTAACGGCTGAA
    CTAGAAATTAATTTATTTATTGATCCTAAAACTGTACAAACTAATGGAAATCAAACTATA
    ACTTCAACACTAAATGAAGAACAAACTTCAAAGGAATTAGATGTTAAATATAAAGATGGT
    ATTGGGAATTATTATGCCAATTTAAATGGATCGATTGAGACATTTAATAAAGCGAATAAT
    AGATTTTCGCATGTTGCATTTATTAAACCTAATAATGGTAAAACGACAAGTGTGACTGTT
    ACTGGAACTTTAATGAAAGGTAGTAATCAGAATGGAAATCAACCAAAAGTTAGGATATTT
    GAATACTTGGGTAATAATGAAGACATAGCGAAGAGTGTATATGCAAATACGACAGATACT
    TCTAAATTTAAAGAAGTCACAAGTAATATGAGTGGGAATTTGAATTTACAAAATAATGGA
    AGCTATTCATTGAATATAGAAAATCTAGATAAAACTTATGTTGTTCACTATGATGGAGAG
    TATTTAAATGGTACTGATGAAGTTGATTTTAGAACACAAATGGTAGGACATCCAGAGCAA
    CTTTATAAGTATTATTATGATAGAGGATATACCTTAACTTGGGATAATGGTTTAGTTTTA
    TACAGTAATAAAGCGAACGGAAATGGGAAAAATGGTCCGATTATTCAAAATAATAAATTT
    GAATATAAAGAAGATACAATTAAAGAAACTCTTACAGGTCAATATGATAAGAATTTAGTA
    ACTACTGTTGAAGAGGAATATGATTCATCAACTCTTGACATTGATTACCACACAGCTATA
    GATGGTGGAGGTGGATATGTTGATGGATACATTGAAACAATAGAAGAAACGGATTCATCA
    GCTATTGATATCGATTACCATACTGCTGTGGATAGCGAAGCAGGTCACGTTGGAGGATAC
    ACTGAGTCCTCTGAGGAATCAAATCCAATTGACTTTGAAGAATCTACACATGAAAATTCA
    AAACATCACGCTGATGTTGTTGAATATGAAGAAGATACAAACCCAGGTGGTGGTCAGGTT
    ACTACTGAGTCTAACTTAGTTGAATTTGACGAAGAGTCTACAAAAGGTATTGTAACTGGC
    GCAGTGAGCGATCATACAACAGTTGAAGATACGAAAGAATATACAACTGAAAGTAATCTG
    ATTGAATTAGTGGATGAATTACCTGAAGAGCATGGTCAAGCACAAGGACCAGTCGAGGAA
    ATTACTGAAAACAATCATCATATTTCTCATTCTGGTTTAGGAACTGAAAATGGTCACGGG
    AATTATGACGTGATTGAAGAAATCGAAGAAAATAGCCACGTTGATATTAAGAGTGAATTA
    GGTTATGAAGGTGGCCAAAATAGCGGTAACCAGTCATTCGAGGAAGACACAGAAGAAGAC
    AAACCTAAATATGAACAAGGTGGCAATATCGTAGATATCGATTTTGATAGTGTACCTCAA
    ATTCATGGTCAAAATAAAGGTAATCAGTCATTCGAGGAAGATACAGAAAAAGACAAACCT
    AAGTATGAACATGGCGGTAACATCATTGATATCGACTTCGACAGTGTGCCACATATTCAC
    GGATTCAATAAGCACACTGAAATTATTGAAGAAGATACAAATAAAGATAAACCAAGTTAT
    CAATTCGGTGGACACAATAGTGTTGACTTTGAAGAAGATACACTTCCAAAAGTAAGCGGC
    CAAAATGAAGGTCAACAAACGATTGAAGAAGATACAACACCTCCAATCGTGCCACCAACG
    CCACCGACACCAGAAGTACCAAGTGAGCCGGAAACACCAACGCCACCAACACCAGAAGTA
    CCAAGTGAGCCGGAAACACCAACACCACCGACACCAGAAGTGCCGAGTGAGCCAGAAACT
    CCAACACCGCCAACACCAGAGGTACCAGCTGAACCTGGTAAACCAGTACCACCTGCCAAA
    GAAGAACCTAAAAAGCCTTCTAAACCAGTGGAACAAGGTAAAGTAGTAACACCTGTTATT
    GAAATCAATGAAAAGGTTAAAGCAGTGGCACCAACTAAAAAACCACAATCTAAGAAATCT
    GAACTACCTGAAACAGGTGGAGAAGAATCAACAAACAAAGGTATGTTGTTCGGCGGATTA
    TTCAGCATTCTAGGTTTAGCATTATTACGCAGAAATAAAAAGAATCACAAAGCATAA
    60
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⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS13155 [old locus tag: SACOL2511 ]
  • symbol: SACOL_RS13155
  • description: fibronectin-binding protein A
  • length: 1018
  • theoretical pI: 4.34254
  • theoretical MW: 111708
  • GRAVY: -0.922495

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 25.1)
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 22)
  • TheSEED: see SACOL2511
  • PFAM:
    Adhesin (CL0204) SdrG_C_C; C-terminus of bacterial fibrinogen-binding adhesin (PF10425; HMM-score: 130.8)
    no clan defined Fn_bind; Fibronectin binding repeat (PF02986; HMM-score: 104.9)
    and 2 more
    Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 34.9)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 32.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 0
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.882163
    • TAT(Tat/SPI): 0.008947
    • LIPO(Sec/SPII): 0.090988
    • Cleavage Site: CS pos: 37-38. AAA-SE. Pr: 0.7401
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTTVEENGNSATDNKTSETQTTATNVNHIEETQSYNATVTEQPSNATQVTTEEAPKAVQAPQTAQPANIETVKEEVVKEEAKPQVKETTQSQDNSGDQRQVDLTPKKATQNQVAETQVEVAQPRTASESKPRVTRSADVAEAKEASNAKVETGTDVTSKVTVEIGSIEGHNNTNKVEPHAGQRAVLKYKLKFENGLHQGDYFDFTLSNNVNTHGVSTARKVPEIKNGSVVMATGEVLEGGKIRYTFTNDIEDKVDVTAELEINLFIDPKTVQTNGNQTITSTLNEEQTSKELDVKYKDGIGNYYANLNGSIETFNKANNRFSHVAFIKPNNGKTTSVTVTGTLMKGSNQNGNQPKVRIFEYLGNNEDIAKSVYANTTDTSKFKEVTSNMSGNLNLQNNGSYSLNIENLDKTYVVHYDGEYLNGTDEVDFRTQMVGHPEQLYKYYYDRGYTLTWDNGLVLYSNKANGNGKNGPIIQNNKFEYKEDTIKETLTGQYDKNLVTTVEEEYDSSTLDIDYHTAIDGGGGYVDGYIETIEETDSSAIDIDYHTAVDSEAGHVGGYTESSEESNPIDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTVEDTKEYTTESNLIELVDELPEEHGQAQGPVEEITENNHHISHSGLGTENGHGNYDVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQNKGNQSFEEDTEKDKPKYEHGGNIIDIDFDSVPHIHGFNKHTEIIEEDTNKDKPSYQFGGHNSVDFEEDTLPKVSGQNEGQQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKKPQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNHKA

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: see SACOL2511
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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