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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS13565 [old locus tag: SACOL2590 ]
  • pan locus tag?: SAUPAN006248000
  • symbol: SACOL_RS13565
  • pan gene symbol?: —
  • synonym:
  • product: glyoxalase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS13565 [old locus tag: SACOL2590 ]
  • symbol: SACOL_RS13565
  • product: glyoxalase
  • replicon: chromosome
  • strand: -
  • coordinates: 2653392..2653769
  • length: 378
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2653392..2653769) NCBI
  • BioCyc: SACOL_RS13565 BioCyc
  • MicrobesOnline: see SACOL2590

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGATTCAATCAATGTGGTTTAATTTGCATGTGCAAGATTTAGAAAAGAGCGCACAGTTT
    TATAAAGCGTTAGGATTTAAAATAAATAGAAACCCACAAATGTTAGATAAAATGGTCGGC
    ATTCAAATAGGTCAAACAACCGTAATTTTAATAGAAAACAAGCATTTTCAAAATGTAAGT
    CAGCAAAGCCTTAATACTGAACCAAATGAAGTGATGATTTCTCTAGGTGTGAACACAAAT
    GAAGAAGTTGACCAGTTGGTGAATAAAGTGAAAGAAGCGGGTGGCACAGTCGTTCAAGAA
    CCAACAGTAAGCCAAGGGTTTTATGGAGCAATGTTCAAAGATCTTGATGGACACCATTTT
    AATTTTTTGGTCTGCTAA
    60
    120
    180
    240
    300
    360
    378

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS13565 [old locus tag: SACOL2590 ]
  • symbol: SACOL_RS13565
  • description: glyoxalase
  • length: 125
  • theoretical pI: 5.54363
  • theoretical MW: 14160.1
  • GRAVY: -0.2224

⊟Function[edit | edit source]

  • TIGRFAM:
    3,4-dihydroxyphenylacetate 2,3-dioxygenase (TIGR02295; EC 1.13.11.15; HMM-score: 23.8)
    Metabolism Energy metabolism Other lactoylglutathione lyase (TIGR00068; EC 4.4.1.5; HMM-score: 23)
    Metabolism Central intermediary metabolism Amino sugars lactoylglutathione lyase (TIGR00068; EC 4.4.1.5; HMM-score: 23)
  • TheSEED: see SACOL2590
  • PFAM:
    Glyoxalase (CL0104) Ble-like_N; Bleomycin resistance protein-like N-terminal (PF22677; HMM-score: 64.4)
    and 7 more
    Glyoxalase; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily (PF00903; HMM-score: 40.5)
    Glyoxalase_6; Glyoxalase-like domain (PF18029; HMM-score: 30.8)
    no clan defined Adhesin_P1_N; Adhesin P1 N-terminal domain (PF18652; HMM-score: 15)
    Glyoxalase (CL0104) 3-dmu-9_3-mt; 3-demethylubiquinone-9 3-methyltransferase (PF06983; HMM-score: 14)
    Glyoxalase_2; Glyoxalase-like domain (PF12681; HMM-score: 14)
    PFK (CL0240) Pfk_N; Phosphofructokinase N-terminal domain yeast (PF18468; HMM-score: 13)
    ZnExoPePases (CL0865) Peptidase_M42; M42 glutamyl aminopeptidase (PF05343; HMM-score: 12.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9956
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0039
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002114
    • TAT(Tat/SPI): 0.000315
    • LIPO(Sec/SPII): 0.000431
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIGQTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGTVVQEPTVSQGFYGAMFKDLDGHHFNFLVC

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2590
  • protein localization: see SACOL2590
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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