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NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01021
  • pan locus tag?: SAUPAN003291000
  • symbol: SAOUHSC_01021
  • pan gene symbol?: thiW
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_01021
  • symbol: SAOUHSC_01021
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 991620..993020
  • length: 1401
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    GTGTTAAAAGTAAGTGATTTACGATTAAAATATCCAAGTGGTCAACGTAAAATTTTCGAT
    CATTTAAATATCACTATTCAAGACAAAGAAAAAGTACTTTTACTCGGTCCTTCTGGTTGC
    GGTAAAAGTACACTTCTGAATGTATTAAGTGGTATTGTTCCTAATTTAATTGAATTACCT
    ATGAAATATGATGAACTAATCGTTGACCCATTAAGTGGCGTTATTTTCCAAGACCCTGAT
    AGCCAGTTTTGTATGCCAAAAGTATACGAAGAACTTGCATTCGTTTTAGAAAATAGACAA
    TTACCACGTGAAGACATGGATGCGTTAATTATCAATGCTTTAAATATGGTCAATTTAAAT
    GTTACCCCTGAAACGTATATCAAAGATTTAAGTGGCGGGATGAAACAGAAATTGGCAATT
    GTTGAAACCATTCTTCAACAATCAAAAACATTGTTTTTAGATGAACCGACAGCAATGTTA
    GATGTTCAAGCAACAGAAGATTTATGGACTAAACTAATTGAACTTTGGGAAGATCAAACG
    GTTGTAATCGTTGAACATAAAGTTAAACACATCTGGAATCATGTCGACCGCGTCATTTTG
    ATGGATTATAACGGAAATATCATTGCCGATGAATGTCCTGAAATCATATTACAGAAGTAT
    GTTCATTTACTCAGTGAATATGGTGTGTGGCATCCACGTGCATGGGAATTCGCACCAAGT
    CGTGTTGACTTTCCAACAACAAACTCACACTTATTACAATTTAAAAATGGACGTATTATT
    CGCGGTAAATCAACATTGCTCTCATTCTCAGATTTAGAAATTGGTCTAGGTGAGTGGATT
    ACAATTACAGGGGCAAATGGTAGTGGTAAAACAACCTTGCTTGAATCAATTATGCAATTG
    ATTAAATATCAAGGTGATGTTTATTTTGAAAATCAGCGTTTAACAAAAATTAAACATGCA
    GCAAAACACATGTACCTAGTTTATCAAAACCCAGAATTACAATTTATAACAAATTCGGTT
    TATGATGAAATTAACATTCATTTTAATCACCTTTCTAAAGATCAAAGTGATGATGAAACG
    ATACAACTTTTAAAACTTTTAGATTTACAAAATGTAAAAGATCAACATCCTTATGAGTTG
    TCTATTGGTCAAAAACGACGCCTTAGCGTAGCTACCGCACTAAGTTCTAAAGCTGATATT
    ATCTTTTTAGATGAACCGACATTTGGACTTGATAGCCATAATACATTCCAGTTGATCAAA
    CTTTTCCAAAAGCGAATTAATTTGGGACAAAGTATTGTCATGGTTACACATGACGATGAA
    ATAATTGAACGTTATCCATCAAGAAGACTTAAAATTTCAGATGGTGCGTTACTAGATTGT
    GATGGTGATACGAATGTATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1401

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_01021
  • symbol: SAOUHSC_01021
  • description: hypothetical protein
  • length: 466
  • theoretical pI: 5.21638
  • theoretical MW: 53316
  • GRAVY: -0.181974

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 245.5)
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 230)
    Cellular processes Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 203.9)
    Metabolism Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 203.9)
    and 101 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 192.6)
    Cellular processes Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 179.2)
    thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 175.7)
    ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 171.2)
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 169.7)
    Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 164.6)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 164.6)
    Metabolism Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 162.9)
    Metabolism Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 162.9)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 161.4)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 161.3)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 160.7)
    Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 159.8)
    Metabolism Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 152.8)
    thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 152.8)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 152.5)
    Metabolism Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 152.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 151.3)
    2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 150.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 144.2)
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 141)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 138.3)
    lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 136.4)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 134.1)
    Metabolism Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 134.1)
    Metabolism Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 132.8)
    Metabolism Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 132)
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 130.9)
    Metabolism Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 127.1)
    proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 126.6)
    ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 124.7)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 123.2)
    D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 119.8)
    Metabolism Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 118.7)
    ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 116.5)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 111.4)
    Cellular processes Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 109.6)
    Metabolism Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 109.6)
    Metabolism Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 107.9)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 104.3)
    Metabolism Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 104.3)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 103.4)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 103.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 103.2)
    Genetic information processing Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 103.2)
    Metabolism Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 103.2)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 99.3)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 98.7)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 98.7)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 97.9)
    gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 96.5)
    Metabolism Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 92.8)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 92.7)
    phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 92.3)
    Metabolism Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 91.5)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 87)
    ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 85.1)
    Metabolism Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 77.9)
    Metabolism Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 76.3)
    Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 75.4)
    Metabolism Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 66.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 64.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 60.1)
    Metabolism Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 53.3)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 52.7)
    Metabolism Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 52)
    Metabolism Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 52)
    P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 30.1)
    Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 24)
    helicase/secretion neighborhood ATPase (TIGR03819; HMM-score: 23.3)
    Metabolism Central intermediary metabolism Phosphorus compounds phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN (TIGR02322; HMM-score: 22.8)
    type IV secretion/conjugal transfer ATPase, VirB4 family (TIGR00929; HMM-score: 21.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaA regulatory inactivator Hda (TIGR03420; HMM-score: 20.1)
    Genetic information processing DNA metabolism Restriction/modification DNA sulfur modification protein DndD (TIGR03185; HMM-score: 19.9)
    Unknown function General Mg chelatase-like protein (TIGR00368; HMM-score: 19.6)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions dTMP kinase (TIGR00041; EC 2.7.4.9; HMM-score: 19.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdopterin-guanine dinucleotide biosynthesis protein B (TIGR00176; HMM-score: 18.3)
    rad50 (TIGR00606; HMM-score: 18.3)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA replication and repair protein RecF (TIGR00611; HMM-score: 18.1)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair checkpoint protein rad24 (TIGR00602; HMM-score: 18)
    Metabolism Energy metabolism Amino acids and amines ethanolamine utilization protein, EutP (TIGR02528; HMM-score: 17.5)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uridine kinase (TIGR00235; EC 2.7.1.48; HMM-score: 16.7)
    Cellular processes Cellular processes Conjugation P-type conjugative transfer ATPase TrbB (TIGR02782; HMM-score: 16.6)
    Genetic information processing Protein synthesis Translation factors ribosome small subunit-dependent GTPase A (TIGR00157; EC 3.6.-.-; HMM-score: 16.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions guanylate kinase (TIGR03263; EC 2.7.4.8; HMM-score: 15.9)
    Cell structure Cell envelope Surface structures twitching motility protein (TIGR01420; HMM-score: 15.3)
    Cellular processes Cellular processes Chemotaxis and motility twitching motility protein (TIGR01420; HMM-score: 15.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCb (TIGR03925; HMM-score: 14.9)
    Dot/Icm secretion system ATPase DotB (TIGR02524; HMM-score: 14.6)
    Metabolism Transport and binding proteins Amino acids, peptides and amines LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 14.4)
    Signal transduction Regulatory functions Protein interactions LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 14.4)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A dephospho-CoA kinase (TIGR00152; EC 2.7.1.24; HMM-score: 13.9)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA 2-selenouridine synthase (TIGR03167; EC 2.9.1.-; HMM-score: 13.7)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking putative secretion ATPase, PEP-CTERM locus subfamily (TIGR03015; HMM-score: 13.5)
    Cellular processes Cellular processes Pathogenesis type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 13.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 13.3)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein YjeE (TIGR00150; HMM-score: 12.8)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair exonuclease SbcC (TIGR00618; HMM-score: 12.2)
    Genetic information processing Protein synthesis Other GTP-binding protein Era (TIGR00436; HMM-score: 12)
    Metabolism Central intermediary metabolism Sulfur metabolism adenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 12)
    Cellular processes Cellular processes Pathogenesis type VI secretion protein IcmF (TIGR03348; HMM-score: 9.3)
  • TheSEED:  
    Membrane Transport Membrane Transport - no subcategory ECF class transporters  Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
  • PFAM:
    P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 159.3)
    and 62 more
    AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 70.5)
    AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 43.3)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 40.1)
    SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 38)
    AAA_23; AAA domain (PF13476; HMM-score: 37.1)
    AAA_15; AAA ATPase domain (PF13175; HMM-score: 34.8)
    AAA_18; AAA domain (PF13238; HMM-score: 32.5)
    T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 31)
    RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 30.6)
    NACHT; NACHT domain (PF05729; HMM-score: 30.5)
    G-alpha; G-protein alpha subunit (PF00503; HMM-score: 30)
    Mg_chelatase; Magnesium chelatase, subunit ChlI (PF01078; HMM-score: 28.2)
    AAA_28; AAA domain (PF13521; HMM-score: 28.2)
    ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 26.2)
    AAA_19; AAA domain (PF13245; HMM-score: 26.1)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 25.8)
    AAA_33; AAA domain (PF13671; HMM-score: 25.8)
    AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 25.7)
    AAA_14; AAA domain (PF13173; HMM-score: 24.9)
    AAA_22; AAA domain (PF13401; HMM-score: 24.6)
    AAA_30; AAA domain (PF13604; HMM-score: 24.6)
    NTPase_1; NTPase (PF03266; HMM-score: 24.1)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 22)
    PduV-EutP; Ethanolamine utilisation - propanediol utilisation (PF10662; HMM-score: 20.7)
    MobB; Molybdopterin guanine dinucleotide synthesis protein B (PF03205; HMM-score: 20.6)
    cobW; CobW/HypB/UreG, nucleotide-binding domain (PF02492; HMM-score: 20)
    AAA_25; AAA domain (PF13481; HMM-score: 20)
    NB-ARC; NB-ARC domain (PF00931; HMM-score: 19.6)
    Rad17; Rad17 cell cycle checkpoint protein (PF03215; HMM-score: 19.5)
    IstB_IS21; IstB-like ATP binding protein (PF01695; HMM-score: 19.2)
    AAA_24; AAA domain (PF13479; HMM-score: 19)
    AAA_17; AAA domain (PF13207; HMM-score: 18.5)
    Roc; Ras of Complex, Roc, domain of DAPkinase (PF08477; HMM-score: 18.4)
    PRK; Phosphoribulokinase / Uridine kinase family (PF00485; HMM-score: 18.3)
    FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 18)
    ABC_ATPase; Predicted ATPase of the ABC class (PF09818; HMM-score: 17.3)
    SbcCD_C; Putative exonuclease SbcCD, C subunit (PF13558; HMM-score: 16.9)
    MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 16.5)
    dNK; Deoxynucleoside kinase (PF01712; HMM-score: 16.3)
    ATP_bind_1; Conserved hypothetical ATP binding protein (PF03029; HMM-score: 16.3)
    Viral_helicase1; Viral (Superfamily 1) RNA helicase (PF01443; HMM-score: 16.2)
    TrwB_AAD_bind; Type IV secretion-system coupling protein DNA-binding domain (PF10412; HMM-score: 16.1)
    PIF1; PIF1-like helicase (PF05970; HMM-score: 15.9)
    Septin; Septin (PF00735; HMM-score: 15.5)
    SRPRB; Signal recognition particle receptor beta subunit (PF09439; HMM-score: 15.3)
    Sigma54_activat; Sigma-54 interaction domain (PF00158; HMM-score: 15.2)
    DAP3; Mitochondrial ribosomal death-associated protein 3 (PF10236; HMM-score: 15.1)
    Zeta_toxin; Zeta toxin (PF06414; HMM-score: 14.9)
    TsaE; Threonylcarbamoyl adenosine biosynthesis protein TsaE (PF02367; HMM-score: 14.8)
    Dynamin_N; Dynamin family (PF00350; HMM-score: 14.2)
    ArgK; ArgK protein (PF03308; HMM-score: 14.1)
    ATP-synt_ab; ATP synthase alpha/beta family, nucleotide-binding domain (PF00006; HMM-score: 13.9)
    KAP_NTPase; KAP family P-loop domain (PF07693; HMM-score: 13.6)
    AAA_13; AAA domain (PF13166; HMM-score: 13.5)
    SRP54; SRP54-type protein, GTPase domain (PF00448; HMM-score: 13.2)
    Thymidylate_kin; Thymidylate kinase (PF02223; HMM-score: 13.2)
    FeoB_N; Ferrous iron transport protein B (PF02421; HMM-score: 12.9)
    RuvB_N; Holliday junction DNA helicase ruvB N-terminus (PF05496; HMM-score: 12.7)
    GvpD; GvpD gas vesicle protein (PF07088; HMM-score: 12.6)
    AAA_27; AAA domain (PF13514; HMM-score: 12.3)
    DUF815; Protein of unknown function (DUF815) (PF05673; HMM-score: 12.2)
    Pox_A32; Poxvirus A32 protein (PF04665; HMM-score: 11)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.0045
    • TAT(Tat/SPI): 0.000346
    • LIPO(Sec/SPII): 0.008263
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQLPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV

Experimental data[edit | edit source]

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator: THI-box (transcription termination) regulon
    THI-box(5' cis-acting region)important in Thiamine biosynthesis; transcription unit transferred from N315 data RegPrecise  

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Maren Depke, Stephan Michalik, Alexander Rabe, Kristin Surmann, Lars Brinkmann, Nico Jehmlich, Jörg Bernhardt, Michael Hecker, Bernd Wollscheid, Zhi Sun, Robert L Moritz, Uwe Völker, Frank Schmidt
    A peptide resource for the analysis of Staphylococcus aureus in host-pathogen interaction studies.
    Proteomics: 2015, 15(21);3648-61
    [PubMed:26224020] [WorldCat.org] [DOI] (I p)
  2. Stephan Michalik, Maren Depke, Annette Murr, Manuela Gesell Salazar, Ulrike Kusebauch, Zhi Sun, Tanja C Meyer, Kristin Surmann, Henrike Pförtner, Petra Hildebrandt, Stefan Weiss, Laura Marcela Palma Medina, Melanie Gutjahr, Elke Hammer, Dörte Becher, Thomas Pribyl, Sven Hammerschmidt, Eric W Deutsch, Samuel L Bader, Michael Hecker, Robert L Moritz, Ulrike Mäder, Uwe Völker, Frank Schmidt
    A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host-pathogen interactions.
    Sci Rep: 2017, 7(1);9718
    [PubMed:28887440] [WorldCat.org] [DOI] (I e)
  3. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]