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NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01387
  • pan locus tag?: SAUPAN003796000
  • symbol: SAOUHSC_01387
  • pan gene symbol?: pstC
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_01387
  • symbol: SAOUHSC_01387
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1330246..1331172
  • length: 927
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGACTTCATCTACTAATGTTAAAGCTTTAATCGAAAAAAATAATAATAAAAAAGGAAAG
    CATAATGACAAAATTATACCAGTTATTTTAGCCGCAATTTCAGCGATTTCCATTTTAACA
    ACACTAGGTATATTAATCACATTGCTTTTAGAAACCATCACTTTTTTCACCAGAATTCCA
    ATAACTGAATTTCTATTTTCTACTACTTGGAATCCTACCGGTTCAGACCCTAAGTTTGGT
    ATCTGGGCATTGATAATAGGGACTTTAAAAATCACAGTTATTGCGACTATATTTGCAGTT
    CCAGTCGGGCTTGGTGCAGCAATTTATTTAAGTGAATATGCAAGTGACCGTGCACGACGC
    ATAATTAAACCGATATTAGAAATTTTAGCAGGAATACCAACAATTGTGTTTGGTTTCTTT
    GCATTAACCTTTGTTACACCAGTATTAAGATCTTTCATACCAGGTCTTGGAGAGTTTAAT
    GCTATAAGTCCCGGCTTAGTTGTCGGTATTATGATTGTCCCTCTCATCACAAGTTTGAGT
    GAGGATGCAATGGCATCTGTACCAAATAAAATTCGAGAAGGTGCCTATGGACTTGGAGCA
    ACTAAATTAGAAGTAGCAACTAAAGTCGTACTTCCCGCAGCAACATCAGGTATTGTAGCT
    TCAATCGTTCTCGCGATTTCAAGAGCAATTGGAGAAACGATGATTGTATCATTAGCGGCA
    GGTAGTTCGCCAACAGCTTCATTAAGTTTAACAAGTTCGATTCAAACAATGACTGGATAT
    ATTGTTGAGATAGCGACAGGTGATGCAACATTTGGATCAAATATTTATTACAGTATTTAT
    GCTGTAGGGTTCACACTATTTATCTTTACCTTAATCATGAATTTACTTTCTCAGTGGATT
    TCTAAGCGTTTTAGGGAGGAGTATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    927

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_01387
  • symbol: SAOUHSC_01387
  • description: hypothetical protein
  • length: 308
  • theoretical pI: 9.67025
  • theoretical MW: 32903.6
  • GRAVY: 0.744156

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstC (TIGR02138; HMM-score: 265.7)
    and 9 more
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 177.6)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 53.5)
    NifC-like ABC-type porter (TIGR01581; HMM-score: 49.4)
    choline ABC transporter, permease protein (TIGR03416; HMM-score: 35)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 32.6)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein (TIGR00969; HMM-score: 30.3)
    2-aminoethylphosphonate ABC transport system, membrane component PhnV (TIGR03255; HMM-score: 20.8)
    2-aminoethylphosphonate ABC transporter, permease protein (TIGR03226; HMM-score: 20.5)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysW (TIGR02140; HMM-score: 16.3)
  • TheSEED  :
    • Phosphate ABC transporter, permease protein PstC
    Phosphorus Metabolism Phosphorus Metabolism - no subcategory High affinity phosphate transporter and control of PHO regulon  Phosphate transport system permease protein PstC (TC 3.A.1.7.1)
    and 1 more
    Phosphorus Metabolism Phosphorus Metabolism - no subcategory Phosphate metabolism  Phosphate transport system permease protein PstC (TC 3.A.1.7.1)
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 75)
    and 1 more
    no clan defined DUF4605; Domain of unknown function (DUF4605) (PF15378; HMM-score: 7.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001337
    • TAT(Tat/SPI): 0.000097
    • LIPO(Sec/SPII): 0.001187
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTSSTNVKALIEKNNNKKGKHNDKIIPVILAAISAISILTTLGILITLLLETITFFTRIPITEFLFSTTWNPTGSDPKFGIWALIIGTLKITVIATIFAVPVGLGAAIYLSEYASDRARRIIKPILEILAGIPTIVFGFFALTFVTPVLRSFIPGLGEFNAISPGLVVGIMIVPLITSLSEDAMASVPNKIREGAYGLGATKLEVATKVVLPAATSGIVASIVLAISRAIGETMIVSLAAGSSPTASLSLTSSIQTMTGYIVEIATGDATFGSNIYYSIYAVGFTLFIFTLIMNLLSQWISKRFREEY

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]