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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01521
  • pan locus tag?: SAUPAN001816000
  • symbol: SAOUHSC_01521
  • pan gene symbol?:
  • synonym:
  • product: SLT orf 636-like protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_01521
  • symbol: SAOUHSC_01521
  • product: SLT orf 636-like protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1468675..1470585
  • length: 1911
  • essential: no DEG

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGGAAAATTTGTATTTAATAAAGGATTTGGGAGCTTTAGCAGGTCGAGATTATAGAGCT
    AAGGAAATACAAAACTTACAAAGAATAGAGCAATTTGCGCTTGGCTTGACAACAGAGTTT
    AAGTTGCATCAGAAAGCTAAAACAATTCAACACTTCGCTGAGCAAATTTATTATAATGGT
    AGATCGCAAGCAGCAGTAAACAAATCTTTACAAAGTCAAATTAACGCACTTGTTGTGGCA
    CCACGTAATAACAGTGCTAATGAGATTGTTCAAGCTCGAGTTAATGTAAACGGCGAAACC
    TTTGACACATTAAAAGAACATTTAGACGATTGGGAAACCAAAACTCAAATTAATAAAGAG
    GAAACTATAAGAGAATTAAATAAGACCAAACAAGAAATTCTTGATATCGAGTATCGTTTT
    GAACCTGATAAGCAAGAATTTTTATTTGTGACAGAACTTGCACCTCTTACAAATGCAGTA
    ATGCAATCCTTCTGGTTTGATAATAGAACAGGCATAGTATACATGACACAAGCTAGAAAT
    AATGGCTATATGCTAAGTCGTCTAAGACCTAATGGTCAATTTATAGACAGCTCATTGATT
    GTAGGTGGGGGTCATGGTACACATAACGGTTATAGATATATTGATGATGAGTTATGGATT
    TATAGTTTTATCTTAAATGGTAATAATGAGAATACATTAGTTCGTTTCAAGTATACGCCT
    AATGTGGAAATTAGCTATGGCAAGTATGGTATGCAAGATGTATTTACAGGACACCCAGAA
    AAACCCTACATCACCCCTGTCATAAATGAAAAAGAAAATAAAATTCTATACAGAATTGAG
    AGACCTAGAAGTCAGTGGGAACTTGAAAACTCAATGAATTATATAGAGATAAGAAGTTTA
    GACGATGTTGATAAAAATATTGATAAAGTTTTGCATAAAATCAGTATCCCTATGAGACTA
    ACAAACGAAACCCAACCAATGCAGGGTGTGACTTTTGATGAAAAATACTTGTATTGGTAT
    ACAGGAGACAGTAATCCAAATAATAGAAACTATTTAACGGCTTTCGATTTAGAAACAGGA
    GAAGAAGCGTATCAGGTTAATGCTGACTATGGTGGAACACTAGATTCATTTCCTGGCGAA
    TTTGCGGAAGCAGAAGGTTTGCAAATATACTATGACAAAGATAGTGGTAAAAAAGCTTTG
    ATGCTAGGTGTTACTGTCGGTGGTGATGGAAATAGAACACATCGTATTTTCATGATTGGG
    CAAAGAGGTATTTTAGAAATACTTCACTCAAGAGGCGTTCCTTTTATCATGAGTGACACA
    GGTGGTAGAGTTAAACCTTTACCAATGAGGCCTGATAAACTTAAGAATCTTGGGATGTTA
    ACAGAGCCAGGTCTTTACTATTTATACACTGATCATACAGTTCAAATCGATGATTTCCCA
    TTACCAAGAGAATGGCGTGATGCAGGTTGGTTCTTGGAAGTTAAGCCACCACAAACTGGC
    GGTGATGTAATTCAGATATTGACGCGTAATAGTTATGCAAGGAATATGATGACTTTTGAA
    AGGGTGCTTTCTGGAAGAACTGGAGACATTTCGGACTGGAATTATGTGCCTAAAAATAGT
    GGTAAATGGGAGAGAGTACCTTCATTCATCACAAAAATGTCAGATATTAACATAGTAGGC
    ATGTCGTTTTATTTAACTACGGATGATACAAAACGTTTTACAGATTTTCCAACTGAACGT
    AAAGGGGTAGCTGGTTGGAACTTATATGTAGAAGCTTCAAACACAGGTGGCTTTGTTCAT
    AGGCTAGTTCGTAATAGTGTTACAGCATCTGCTGAGATACTATTGAAAAATTATGATAGT
    AAAACAAGTTCAGGGCCATGGACTTTACACGAAGGGAGAATTATAAGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1911

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_01521
  • symbol: SAOUHSC_01521
  • description: SLT orf 636-like protein
  • length: 636
  • theoretical pI: 5.9963
  • theoretical MW: 73104.9
  • GRAVY: -0.568082

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Phage host receptor binding protein, recognizes GlcNAc moieties on wall teichoic acids
    Cell Wall and Capsule Gram-Positive cell wall components Teichoic and lipoteichoic acids biosynthesis  Putative major teichoic acid biosynthesis protein C
  • PFAM:
    Beta_propeller (CL0186) PQQ; PQQ enzyme repeat (PF01011; HMM-score: 13.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004629
    • TAT(Tat/SPI): 0.000664
    • LIPO(Sec/SPII): 0.000698
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MENLYLIKDLGALAGRDYRAKEIQNLQRIEQFALGLTTEFKLHQKAKTIQHFAEQIYYNGRSQAAVNKSLQSQINALVVAPRNNSANEIVQARVNVNGETFDTLKEHLDDWETKTQINKEETIRELNKTKQEILDIEYRFEPDKQEFLFVTELAPLTNAVMQSFWFDNRTGIVYMTQARNNGYMLSRLRPNGQFIDSSLIVGGGHGTHNGYRYIDDELWIYSFILNGNNENTLVRFKYTPNVEISYGKYGMQDVFTGHPEKPYITPVINEKENKILYRIERPRSQWELENSMNYIEIRSLDDVDKNIDKVLHKISIPMRLTNETQPMQGVTFDEKYLYWYTGDSNPNNRNYLTAFDLETGEEAYQVNADYGGTLDSFPGEFAEAEGLQIYYDKDSGKKALMLGVTVGGDGNRTHRIFMIGQRGILEILHSRGVPFIMSDTGGRVKPLPMRPDKLKNLGMLTEPGLYYLYTDHTVQIDDFPLPREWRDAGWFLEVKPPQTGGDVIQILTRNSYARNMMTFERVLSGRTGDISDWNYVPKNSGKWERVPSFITKMSDINIVGMSFYLTTDDTKRFTDFPTERKGVAGWNLYVEASNTGGFVHRLVRNSVTASAEILLKNYDSKTSSGPWTLHEGRIIS

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]