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NCBI: 03-AUG-2016
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus NCTC8325
- locus tag: SAOUHSC_02464
- pan locus tag?: SAUPAN005611000
- symbol: SAOUHSC_02464
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAOUHSC_02464
- symbol: SAOUHSC_02464
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 2287360..2288214
- length: 855
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3919027 NCBI
- RefSeq: YP_500932 NCBI
- BioCyc: G1I0R-2330 BioCyc
- MicrobesOnline: 1290903 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841ATGAATAAAACAAACTTTGGGGCTTATTTAAATAAAAGTAAGAGCAGGAAAATATATAAG
ATTTTTGATCAAAATTTGAAGCGAGAGTTTAGTTATTGGCAGTTTAGGAAACTTTTCAAA
TCTTATACAAGGCAGTCTGATGTACATGAATTAAAAGTGTGTACTCAAAATGATGGTACT
ATTGAGCAAATATGGATAGATGAAGCAAATCAATTTGGAGTGTCAGTGACTTGGAAAGAT
AATAGTATTATCGGATTTGTTATGCGTCCGTTAATTAATTATGATGCGATTAAGAATGAA
ACGACTTTAAAATACGCAGTGCCGACAACAGATTGCTATGAGATTTTTTGGGGTGGAGAT
AATGAATTATATAATTATCACTATTTATACCCACATCAAAGGTATGCTATTGATTTAGTT
ATTAAAGAAAATCATAAAACATATAAGAATCAAGGAAAAGTAAATACTGATTATTTTTGT
TTTGGAAAAGATATCATTGCGCCAGCAAATGGTACAGTTGAAAAAGTAGTGAATGGGGTT
CAAGACAACAGTATTGGAAGTACGAATGAATCACAGTTTTTAGGAAATTATATTGTAATT
AAGCACGCAGAAAATGAGTATAGCTTAATAGCTCATTTACACCAATATTCAATCATTGTG
AATGAGGGGCAAAATGTTAAATATGGTGATATCATTGGGAAGGTTGGGAATTCTGGCAAT
TCTACTGAACCTCATATACATTTTCAAGTAATGAATGATAAGAATATTGAAGCATGTACA
TCTTTAAAAATTCGATTTATAAATAATCGAGAACTTATCAAAGGGGATGTGGTCTGCGGA
TTACAAGCTGAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAOUHSC_02464
- symbol: SAOUHSC_02464
- description: hypothetical protein
- length: 284
- theoretical pI: 7.58252
- theoretical MW: 32802.7
- GRAVY: -0.527465
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED :
- Peptidase, M23/M37 family
- PFAM: Hybrid (CL0105) Peptidase_M23; Peptidase family M23 (PF01551; HMM-score: 73)and 3 moreRnfC_N; RnfC Barrel sandwich hybrid domain (PF13375; HMM-score: 13.5)Biotin_lipoyl; Biotin-requiring enzyme (PF00364; HMM-score: 13.1)no clan defined NADHdh_A3; NADH dehydrogenase 1 alpha subcomplex subunit 3 (PF14987; HMM-score: 12)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.005315
- TAT(Tat/SPI): 0.000294
- LIPO(Sec/SPII): 0.000684
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNKTNFGAYLNKSKSRKIYKIFDQNLKREFSYWQFRKLFKSYTRQSDVHELKVCTQNDGTIEQIWIDEANQFGVSVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEIFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKNQGKVNTDYFCFGKDIIAPANGTVEKVVNGVQDNSIGSTNESQFLGNYIVIKHAENEYSLIAHLHQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGDVVCGLQAE
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- predicted SigA promoter [1] : SAOUHSC_02464 < S956 < SAOUHSC_02465
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: [1] Multi-gene expression profiles
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ 1.0 1.1 Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
PLoS Genet: 2016, 12(4);e1005962
[PubMed:27035918] [WorldCat.org] [DOI] (I e)