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NCBI: 03-AUG-2016

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_02998
  • pan locus tag?: SAUPAN006407000
  • symbol: SAOUHSC_02998
  • pan gene symbol?: cap1C
  • synonym:
  • product: capsular polysaccharide biosynthesis protein Cap5C

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_02998
  • symbol: SAOUHSC_02998
  • product: capsular polysaccharide biosynthesis protein Cap5C
  • replicon: chromosome
  • strand: -
  • coordinates: 2771466..2772233
  • length: 768
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGATTGATATTCATAACCATATATTAGTTGATATAGATGATGGTCCTAAAACAATTGAA
    AAGAGTATTGCACTATTAAAGCAAGCTAAGGATGAAGGTGTAACAAGTATTGTAGCGACA
    CCTCATCATTTGCATCCGAGATATGATAATACATTTCAACAAGTGCTTGTGAAATTGGCG
    GAGTTAAGAACGCATCCAGAAGTTCAAGCATTGGATATTAAATTATTTCCCGGGCAAGAA
    ATTAGAATTACAGATTCGATTCTGAAAGGCTTAGATAATGGTAGTATTCAAGGTATTAAT
    CGTTCGAAATATTTATTAATTGAATTTCCAACGGGCGAAGTACCACATTATACAAAACAA
    TTGTTTTTTGAAATACAATCGAGAGGTTACATACCAATCATTGCACATCCTGAAAGAAAT
    AGAAGTATCGCCAAAAATCCGGAAATATTATATGAATTGGTTGCAAATGGGGCACTGAGT
    CAATTAACATCGAGTTCTTTAGTTGGTGGATTTGGTAAAAACATTCAAAAGTTATCATTA
    CAATTTATAGAATGTAATTTGGCTCATTTTGTAGCTTCAGATGCACATTCATGTGACCAA
    AGACCATTTTTGATGCAAGAATTATTTCACAATCATAAATTGAAGAAATATTCGAATGAT
    ATTGAAGCATTACTTCGAAATGCCAGTTCAGTAATCAATGATAATTTTGTTTATTTAGAC
    AGACCGACTAAGCCAGGAAAAGTGAAGTCGTTTTTGAAATGGTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    768

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAOUHSC_02998
  • symbol: SAOUHSC_02998
  • description: capsular polysaccharide biosynthesis protein Cap5C
  • length: 255
  • theoretical pI: 8.26306
  • theoretical MW: 28917
  • GRAVY: -0.251765

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Manganese-dependent protein-tyrosine phosphatase (EC 3.1.3.48)
    Cell Wall and Capsule Capsular and extracellular polysacchrides Exopolysaccharide Biosynthesis  Manganese-dependent protein-tyrosine phosphatase (EC 3.1.3.48)
    and 1 more
    Regulation and Cell signaling Regulation and Cell signaling - no subcategory Cell envelope-associated LytR-CpsA-Psr transcriptional attenuators  Manganese-dependent protein-tyrosine phosphatase (EC 3.1.3.48)
  • PFAM:

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002178
    • TAT(Tat/SPI): 0.000224
    • LIPO(Sec/SPII): 0.00039
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHLHPRYDNTFQQVLVKLAELRTHPEVQALDIKLFPGQEIRITDSILKGLDNGSIQGINRSKYLLIEFPTGEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPEILYELVANGALSQLTSSSLVGGFGKNIQKLSLQFIECNLAHFVASDAHSCDQRPFLMQELFHNHKLKKYSNDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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