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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

Summary[edit | edit source]

  • pan ID?: SAUPAN000520000
  • symbol?:
  • synonym:
  • description?: TIGR01741 family protein
  • strand?: +
  • coordinates?: 603494..624995
  • synteny block?: BlockID0002460
  • occurrence?: in 15% of 34 strains

essI (esaG) : tandem EssD nuclease immunity protein paralogue [1]

• This locus is highly prone to recombination leading to gene duplication / loss. Gene nomenclature is confusing and appears to be numbered sequentially by position in the genome and is not intended to show homology between strains (e.g. the first instance of essI/esaG in COL may have the greatest homology with the sixth instance in FPR3757 but the gene names would still be different [i.e. essI1/esaG1 and essI6/esaG6 in COL and FPR3757, respectively]). Likewise, pseudogenes are frequent and assigned gene nomenclature in this locus. As appropriate, please append a numeral to the gene names provided here consistent with the number of gene duplications in your genome of interest.

Orthologs[edit | edit source]

    COL:
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    04-02981:
    08BA02176:
    11819-97:
    6850:
    71193:
    ECT-R 2:
    ED133:
    ED98:
    HO 5096 0412:
    SAEMRSA15_02570
    JH1:
    JH9:
    JKD6008:
    JKD6159:
    JSNZ:
    LGA251:
    M013:
    MRSA252:
    MSHR1132:
    SAMSHR1132_02650
    MSSA476:
    Mu3:
    Mu50:
    MW2:
    RF122:
    ST398:
    T0131:
    SAT0131_00296 (ruvB)
    TCH60:
    TW20:
    SATW20_03000
    USA300_TCH1516:
    VC40:

Genome Viewer[edit | edit source]

Alignments[edit | edit source]

  • alignment of orthologues:

  1. Ryan Jay Ohr, Mark Anderson, Miaomiao Shi, Olaf Schneewind, Dominique Missiakas
    EssD, a Nuclease Effector of the Staphylococcus aureus ESS Pathway.
    J Bacteriol: 2017, 199(1);
    [PubMed:27795323] [WorldCat.org] [DOI] (I e)
    Stephen R Garrett, Giuseppina Mariano, Jo Dicks, Tracy Palmer
    Homologous recombination between tandem paralogues drives evolution of a subset of type VII secretion system immunity genes in firmicute bacteria.
    Microb Genom: 2022, 8(8);
    [PubMed:35960642] [WorldCat.org] [DOI] (I p)