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⊟Summary[edit | edit source]
- pan ID?: SAUPAN000891000
- symbol?: —
- synonym:
- description?: AraC family transcriptional regulator
- AraC family transcriptional regulator
- helix-turn-helix domain-containing protein
- putative AraC family transcriptional regulator
- Amino-terminal domain protein
- AraC family regulatory protein
- bacterial regulatory helix-turn-helix s, AraC family protein
- bifunctional AraC family transcriptional regulator/xylan 1,4-beta-xylosidase
- HTH-type transcriptional regulator
- HTH-type transcriptional regulator AraC
- pseudogene
- putative regulatory protein
- putative transcriptional regulator
- regulatory helix-turn-helix proteins, AraC family protein
- transcriptional regulator, AraC family
- xylan 1,4-beta-xylosidase
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 1156225..1158474
- synteny block?: BlockID0004300
- occurrence?: in 100% of 33 strains
aryK: global virulence-associated regulon transcriptional activator [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0101
08BA02176:
C248_0091
11819-97:
MS7_0095
6850:
RSAU_000058
71193:
ST398NM01_0115
ECT-R 2:
ECTR2_58
ED133:
SAOV_0051
ED98:
SAAV_0069
HO 5096 0412:
SAEMRSA15_00700
JH1:
SaurJH1_0092
JH9:
SaurJH9_0089
JKD6008:
SAA6008_00082
JKD6159:
SAA6159_00085
LGA251:
SARLGA251_00770
M013:
M013TW_0091
MRSA252:
SAR0107
MSHR1132:
SAMSHR1132_00770
MSSA476:
SAS0078
Mu3:
SAHV_0100
Mu50:
SAV0101
MW2:
MW0077
RF122:
SAB0041
ST398:
SAPIG0115
T0131:
SAT0131_00084 (zwf)
TCH60:
HMPREF0772_10393
TW20:
SATW20_01160
USA300_TCH1516:
USA300HOU_0113
VC40:
SAVC_00250
⊟Genome Viewer[edit | edit source]
COL | |
N315 | |
NCTC8325 | |
Newman | |
USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL -------------MSDFKRLNSLMIGFVIKGEAHIYDENNMTQCNSGDIFIINHRDLYRF
N315 MQRDYLIRVETESMPDFKRLNGLMIGFVIKGEAHIYDENNMTQCNSGDIFIINHRDLYRF
NCTC8325 -------------MSDFKRLNSLMIGFVIKGEAHIYDENNMTQCNSGDIFIINHRDLYRF
Newman MQRDYLIRVETESMSDFKRLNSLMIGFVIKGEAHIYDENNMTQCNSGDIFIINHRDLYRF
USA300_FPR3757 -------------MSDFKRLNSLMIGFVIKGEAHIYDENNMTQCNSGDIFIINHRDLYRF
*.******.**************************************
COL QLQQDGIICYIQFQMKYLADKFDDVHCLYFHLTDATTTKNIHQLRNIMARLVSTHIRHNE
N315 QLQQDGIICYIQFQMKYLADKFDDAHCLYFHLTDATTTKNIHQLRNIMARLVSTHIRHNE
NCTC8325 QLQQDGIICYIQFQMKYLADKFDDVHCLYFHLTDATTTKNIHQLRNIMARLVSTHIRHNE
Newman QLQQDGIICYIQFQMKYLADKFDDVHCLYFHLTDATTTKNIHQLRNIMARLVSTHIRHNE
USA300_FPR3757 QLQQDGIICYIQFQMKYLADKFDDVHCLYFHLTDATTTKNIHQLRNIMARLVSTHIRHNE
************************.***********************************
COL LSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQVCDYIELHFHEDLSLSELSEY
N315 LSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQVCDYIELHFHEDLSLSELSEY
NCTC8325 LSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQVCDYIELHFHEDLSLSELSEY
Newman LSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQVCDYIELHFHEDLSLSELSEY
USA300_FPR3757 LSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQVCDYIELHFHEDLSLSELSEY
************************************************************
COL VGWSESHLSKKFTESLGVGFHHFLNTTRIEHAKLDLTYTDETITDIALQNGFSSAASFAR
N315 VGWSESHLSKKFTESLGVGFQHFLNTTRIEHAKLDLTYTDETITDIALQNGFSSAASFAR
NCTC8325 VGWSESHLSKKFTESLGVGFHHFLNTTRIEHAKLDLTYTDETITDIALQNGFSSAASFAR
Newman VGWSESHLSKKFTESLGVGFHHFLNTTRIEHAKLDLTYTDETITDIALQNGFSSAASFAR
USA300_FPR3757 VGWSESHLSKKFTESLGVGFHHFLNTTRIEHAKLDLTYTDETITDIALQNGFSSAASFAR
********************:***************************************
COL TFKHFTHQTPKQYRGDRPAITENQQSAQHDYHDRELILLLNDYIEEMNHFIEDIEKMNYK
N315 TFKHFTHQTPKQYRGDRPAITENQQSAQHNYHDRELILLLNDYIEEMNHFIEDIEKMNYK
NCTC8325 TFKHFTHQTPKQYRGDRPAITENQQSAQHDYHDRELILLLNDYIEEMNHFIEDIEKMNYK
Newman TFKHFTHQTPKQYRGDRPAITENQQSAQHDYHDRELILLLNDYIEEMNHFIEDIEKMNYK
USA300_FPR3757 TFKHFTHQTPKQYRGDRPAITENQQSAQHDYHDRELILLLNDYIEEMNHFIEDIEKMNYK
*****************************:******************************
COL EIAFQPTNHQLNQFNHIIQVGYLRNLLNTQYQSQLLTCHHDFQVNEVLAYDVIPYIMKKL
N315 EIAFKPTNQQLNQFNHIIQVGYLRNLLNTQYQSQLLTCHHDFQVNEVLAYDVMPYIMKKL
NCTC8325 EIAFQPTNHQLNQFNHIIQVGYLRNLLNTQYQSQLLTCHHDFQVNEVLAYDVIPYIMKKL
Newman EIAFQPTNHQLNQFNHIIQVGYLRNLLNTQYQSQLLTCHHDFQVNEVLAYDVIPYIMKKL
USA300_FPR3757 EIAFQPTNHQLNQFNHIIQVGYLRNLLNTQYQSQLLTCHHDFQVNEVLAYDVIPYIMKKL
****:***:*******************************************:*******
COL NAPFTYDAEISNIFYDIDLCLDFLLDHNFSLTMHLDQYDSRDYIDAFKIFIHHVALHVSH
N315 NAPFTYDAEISNIFYDIDLCLDFLLDHNFSLTMHLNQYDSRDYIDAFKVFIHHVALHVSH
NCTC8325 NAPFTYDAEISNIFYDIDLCLDFLLDHNFSLTMHLDQYDSRDYIDAFKIFIHHVALHVSH
Newman NAPFTYDAEISNIFYDIDLCLDFLLDHNFSLTMHLDQYDSRDYIDAFKIFIHHVALHVSH
USA300_FPR3757 NAPFTYDAEISNIFYDIDLCLDFLLDHNFSLTMHLDQYDSRDYIDAFKIFIHHVALHVSH
***********************************:************:***********
COL RKDLKFNLYVTTLHTSLIEMIDYFKALFPNGGLYIHLDQATERHLPLLKRLEPHIDHFVF
N315 RKDLKFNLYVTTLHTSLIEMIDYFKALFPNGGLYIHLDQATERHLPLLKRLEPHINHFVF
NCTC8325 RKDLKFNLYVTTLHTSLIEMIDYFKALFPNGGLYIHLDQATERHLPLLKRLEPHIDHFVF
Newman RKDLKFNLYVTTLHTSLIEMIDYFKALFPNGGLYIHLDQATERHLPLLKRLEPHIDHFVF
USA300_FPR3757 RKDLKFNLYVTTLHTSLIEMIDYFKALFPNGGLYIHLDQATERHLPLLKRLEPHIDHFVF
*******************************************************:****
COL DANSNDAVDFNKMNDDEFKTASQMIINKTNYLIDLMHRHRLKRPLILLNWNTLTGDTFIT
N315 DANSNDAVDFNKMNDDEFKTASQMIINKTNYLIDLMHRHNLKRPLILLNWNTLTGDTFIT
NCTC8325 DANSNDAVDFNKMNDDEFKTASQMIINKTNYLIDLMHRHRLKRPLILLNWNTLTGDTFIT
Newman DANSNDAVDFNKMNDDEFKTASQMIINKTNYLIDLMHRHRLKRPLILLNWNTLTGDTFIT
USA300_FPR3757 DANSNDAVDFNKMNDDEFKTASQMIINKTNYLIDLMHRHRLKRPLILLNWNTLTGDTFIT
***************************************.********************
COL NGEYFRGGIIIEQLLKLSSKVEGIGYWLNYDLHVSHCKNERDYMNSIELFHQYNGKRPVY
N315 NGEYFRGGIIIEQLLKLSTKVEGIGYWLNYDLHVSHCRNERDYMNSIELFHQYNGKRPVY
NCTC8325 NGEYFRGGIIIEQLLKLSSKVEGIGYWLNYDLHVSHCKNERDYMNSIELFHQYNGKRPVY
Newman NGEYFRGGIIIEQLLKLSSKVEGIGYRLNYDLHVSHCKNERDYMNSIELFHQYNGKRPVY
USA300_FPR3757 NGEYFRGGIIIEQLLKLSSKVEGIGYWLNYDLHVSHCKNERDYMNSIELFHQYNGKRPVY
******************:******* **********:**********************
COL FTALLFNKLTSNILYSDDTCIVTGTDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLN
N315 FTALLFNKLTSNILYSDDTCIVTGTDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLN
NCTC8325 FTALLFNKLTSNILYSDDTCIVTGTDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLN
Newman FTALLFNKLTSNILYSDDTCIVTGTDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLN
USA300_FPR3757 FTALLFNKLTSNILYSDDTCIVTGTDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLN
************************************************************
COL INALEEGMYKIKHFTLDKENGALFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDIT
N315 INALEDGMYKIKHFTLDKENGALFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDIT
NCTC8325 INALEEGMYKIKHFTLDKENGALFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDIT
Newman INALEEGMYKIKHFTLDKENGALFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDIT
USA300_FPR3757 INALEEGMYKIKHFTLDKENGALFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDIT
*****:******************************************************
COL DTLALNIKMITNGIHLIEVKRYPSS
N315 DTLALNIKMITNGIHLIEVKRYPSS
NCTC8325 DTLALNIKMITNGIHLIEVKRYPSS
Newman DTLALNIKMITNGIHLIEVKRYPSS
USA300_FPR3757 DTLALNIKMITNGIHLIEVKRYPSS
*************************
- ↑ Kyra Y L Chua, Ian R Monk, Ya-Hsun Lin, Torsten Seemann, Kellie L Tuck, Jessica L Porter, Justin Stepnell, Geoffrey W Coombs, John K Davies, Timothy P Stinear, Benjamin P Howden
Hyperexpression of α-hemolysin explains enhanced virulence of sequence type 93 community-associated methicillin-resistant Staphylococcus aureus.
BMC Microbiol: 2014, 14;31
[PubMed:24512075] [WorldCat.org] [DOI] (I e)