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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

Summary[edit | edit source]

  • pan ID?: SAUPAN001835000
  • symbol?:
  • synonym:
  • description?: terminase

      descriptions from strain specific annotations:

    • terminase
    • phiSLT ORF 101-like protein, terminase, small subunit
    • prophage L54a, terminase, small subunit
    • terminase small subunit
    • phage terminase, small subunit
    • phage terminase, small subunit, , P27
    • phage terminase small subunit
    • phage terminase small subunit P27
  • strand?: -
  • coordinates?: 2286299..2286604
  • synteny block?: BlockID0012110
  • occurrence?: in 44% of 34 strains

terS : serogroup A cos-type terminase small subunit [1]

Prophage terminase complexes assist in transferring the prophage genome into phage capsids. The cos-type terminase small subunit recruits viral genome concatemers to the terminase-capsid complex and presents the cos site to the large terminase. The large terminase proceeds to load the viral genome into capsids, assisted by hnh nuclease cleavage at cos sites.

Orthologs[edit | edit source]

    COL:
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    04-02981:
    08BA02176:
    C248_0348
    11819-97:
    MS7_1469
    6850:
    71193:
    ECT-R 2:
    ED133:
    ED98:
    SAAV_2033
    HO 5096 0412:
    SAEMRSA15_13750
    JH1:
    SaurJH1_1078
    JH9:
    SaurJH9_1058
    JKD6008:
    JKD6159:
    JSNZ:
    LGA251:
    M013:
    MRSA252:
    SAR1520
    MSHR1132:
    MSSA476:
    SAS0931
    Mu3:
    Mu50:
    MW2:
    MW1402
    RF122:
    ST398:
    SAPIG0372
    T0131:
    TCH60:
    HMPREF0772_11689
    TW20:
    USA300_TCH1516:
    USA300HOU_1454
    VC40:

Genome Viewer[edit | edit source]

COL
NCTC8325
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             MKLTKKQLKEYIEDYKKSDDILINLYIETYEFYCRLRDELKNSDLMIEHTNKAGASNIIK
    NCTC8325        MKLTKKQLKEYIEDYKKSDDILINLYIETYEFYCRLRDELKNSDLMIEHTNKAGASNIVK
    USA300_FPR3757  MKLTKKQLKEYIEDYKKSDDILINLYIETYEFYCRLRDELKNSDLMIEHTNKAGASNIVK
                    **********************************************************:*

    COL             NPLSIELTKTVQTLNNLLKSMGLTAAQRKKIVQEEGGFGDY
    NCTC8325        NPLSIELTKTVQTLNNLLKSMGLTAAQRKKIVQEEGGFGDY
    USA300_FPR3757  NPLSIELTKTVQTLNNLLKSMGLTAAQRKKIVQEEGGFGDY
                    *****************************************

  1. Michael Feiss, Venigalla B Rao
    The bacteriophage DNA packaging machine.
    Adv Exp Med Biol: 2012, 726;489-509
    [PubMed:22297528] [WorldCat.org] [DOI] (P p)
    Smriti Kala, Nichole Cumby, Paul D Sadowski, Batool Zafar Hyder, Voula Kanelis, Alan R Davidson, Karen L Maxwell
    HNH proteins are a widespread component of phage DNA packaging machines.
    Proc Natl Acad Sci U S A: 2014, 111(16);6022-7
    [PubMed:24711378] [WorldCat.org] [DOI] (I p)