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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary[edit | edit source]

  • pan ID?: SAUPAN001835000
  • symbol?: —
  • synonym:
  • description?: terminase

      descriptions from strain specific annotations:

    • terminase
    • phiSLT ORF 101-like protein, terminase, small subunit
    • prophage L54a, terminase, small subunit
    • terminase small subunit
    • phage terminase, small subunit
    • phage terminase, small subunit, , P27
    • phage terminase small subunit
    • phage terminase small subunit P27
  • strand?: -
  • coordinates?: 2286299..2286604
  • synteny block?: BlockID0012110
  • occurrence?: in 44% of 34 strains

⊟Additional information (user-provided)[edit | edit source]

terS : serogroup A cos-type terminase small subunit [1]

Prophage terminase complexes assist in transferring the prophage genome into phage capsids. The cos-type terminase small subunit recruits viral genome concatemers to the terminase-capsid complex and presents the cos site to the large terminase. The large terminase proceeds to load the viral genome into capsids, assisted by hnh nuclease cleavage at cos sites.

⊟Orthologs[edit | edit source]

    COL:
    N315:
    —
    NCTC8325:
    Newman:
    —
    USA300_FPR3757:
    JSNZ:
    —
    04-02981:
    —
    08BA02176:
    C248_0348
    11819-97:
    MS7_1469
    6850:
    —
    71193:
    —
    ECT-R 2:
    —
    ED133:
    —
    ED98:
    SAAV_2033
    HO 5096 0412:
    SAEMRSA15_13750
    JH1:
    SaurJH1_1078
    JH9:
    SaurJH9_1058
    JKD6008:
    —
    JKD6159:
    —
    LGA251:
    —
    M013:
    —
    MRSA252:
    SAR1520
    MSHR1132:
    —
    MSSA476:
    SAS0931
    Mu3:
    —
    Mu50:
    —
    MW2:
    MW1402
    RF122:
    —
    ST398:
    SAPIG0372
    T0131:
    —
    TCH60:
    HMPREF0772_11689
    TW20:
    —
    USA300_TCH1516:
    USA300HOU_1454
    VC40:
    —

⊟Genome Viewer[edit | edit source]

COL
NCTC8325
USA300_FPR3757

⊟Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.505)


    COL             MKLTKKQLKEYIEDYKKSDDILINLYIETYEFYCRLRDELKNSDLMIEHTNKAGASNIIK
    NCTC8325        MKLTKKQLKEYIEDYKKSDDILINLYIETYEFYCRLRDELKNSDLMIEHTNKAGASNIVK
    USA300_FPR3757  MKLTKKQLKEYIEDYKKSDDILINLYIETYEFYCRLRDELKNSDLMIEHTNKAGASNIVK
                    **********************************************************:*

    COL             NPLSIELTKTVQTLNNLLKSMGLTAAQRKKIVQEEGGFGDY
    NCTC8325        NPLSIELTKTVQTLNNLLKSMGLTAAQRKKIVQEEGGFGDY
    USA300_FPR3757  NPLSIELTKTVQTLNNLLKSMGLTAAQRKKIVQEEGGFGDY
                    *****************************************

⊟Literature[edit | edit source]

  1. ↑ Michael Feiss, Venigalla B Rao
    The bacteriophage DNA packaging machine.
    Adv Exp Med Biol: 2012, 726;489-509
    [PubMed:22297528] [WorldCat.org] [DOI] (P p)
    Smriti Kala, Nichole Cumby, Paul D Sadowski, Batool Zafar Hyder, Voula Kanelis, Alan R Davidson, Karen L Maxwell
    HNH proteins are a widespread component of phage DNA packaging machines.
    Proc Natl Acad Sci U S A: 2014, 111(16);6022-7
    [PubMed:24711378] [WorldCat.org] [DOI] (I p)