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⊟Summary[edit | edit source]
- pan ID?: SAUPAN002605000
- symbol?: ltaS
- synonym:
- description?: lipoteichoic acid synthase
- lipoteichoic acid synthase
- lipoteichoic acid synthase, type Ib, putative
- polyglycerol-phosphate lipoteichoic acid synthase LtaS
- sulfatase
- sulfatase family protein
- anion-binding protein
- Glycerol phosphate lipoteichoic acid synthase
- Lipoteichoic acid synthase LtaS Type Ib
- phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase
- phosphoglycerol transferase I
- Processed glycerol phosphate lipoteichoic acid synthase
- putative sulfatase
- transmembrane sulfatase
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 3114132..3116139
- synteny block?: BlockID0018410
- occurrence?: in 100% of 33 strains
ltaS: polyglycerol-phosphate lipoteichoic acid synthase [1]
A crystal structure is available: 2W5Q
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0696
08BA02176:
C248_0803
11819-97:
MS7_0770 (ltaS)
6850:
RSAU_000693 (ltaS)
71193:
ST398NM01_0796
ECT-R 2:
ECTR2_669
ED133:
SAOV_0753
ED98:
SAAV_0680
HO 5096 0412:
SAEMRSA15_06450
JH1:
SaurJH1_0759
JH9:
SaurJH9_0742
JKD6008:
SAA6008_00734
JKD6159:
SAA6159_00673
LGA251:
SARLGA251_06520
M013:
M013TW_0705
MRSA252:
SAR0772
MSHR1132:
SAMSHR1132_06640
MSSA476:
SAS0684
Mu3:
SAHV_0716
Mu50:
SAV0719
MW2:
MW0681
RF122:
SAB0668
ST398:
SAPIG0796
T0131:
SAT0131_00788
TCH60:
HMPREF0772_12468
TW20:
SATW20_07940
USA300_TCH1516:
USA300HOU_0742
VC40:
SAVC_03225
⊟Genome Viewer[edit | edit source]
COL | |
N315 | |
NCTC8325 | |
Newman | |
USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
N315 MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
NCTC8325 MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
Newman MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
USA300_FPR3757 MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
************************************************************
COL FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
N315 FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
NCTC8325 FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
Newman FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
USA300_FPR3757 FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
************************************************************
COL KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
N315 KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
NCTC8325 KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
Newman KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
USA300_FPR3757 KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
************************************************************
COL LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
N315 LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
NCTC8325 LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
Newman LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
USA300_FPR3757 LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
************************************************************
COL YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKT
N315 YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKT
NCTC8325 YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKT
Newman YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKT
USA300_FPR3757 YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKT
************************************************************
COL SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
N315 SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
NCTC8325 SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
Newman SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
USA300_FPR3757 SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
************************************************************
COL KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
N315 KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
NCTC8325 KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
Newman KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
USA300_FPR3757 KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
************************************************************
COL LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
N315 LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
NCTC8325 LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
Newman LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
USA300_FPR3757 LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
************************************************************
COL ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
N315 ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
NCTC8325 ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
Newman ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
USA300_FPR3757 ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
************************************************************
COL TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
N315 TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
NCTC8325 TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
Newman TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
USA300_FPR3757 TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
************************************************************
COL QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
N315 QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
NCTC8325 QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
Newman QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
USA300_FPR3757 QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
**********************************************
- ↑ Duo Lu, Mirka E Wörmann, Xiaodong Zhang, Olaf Schneewind, Angelika Gründling, Paul S Freemont
Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS.
Proc Natl Acad Sci U S A: 2009, 106(5);1584-9
[PubMed:19168632] [WorldCat.org] [DOI] (I p)