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⊟Summary[edit | edit source]
- pan ID?: SAUPAN002657000
- symbol?: fakB1
- synonym:
- description?: degV family protein
- degV family protein
- degV family fatty acid transport protein
- fatty acid kinase binding subunit FakB1
- Conserved hypothetical DegV family protein
- DegV domain-containing protein
- EDD, DegV family domain protein
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 3154482..3155588
- synteny block?: BlockID0018920
- occurrence?: in 97% of 34 strains
fakB1 : fatty acid kinase saturated fatty acid binding protein [1]
• A crystal structure is available : 7SCL
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0727
08BA02176:
C248_0836
11819-97:
MS7_0799
6850:
RSAU_000724
71193:
ST398NM01_0825
ECT-R 2:
ECTR2_699
ED133:
SAOV_0786
ED98:
SAAV_0711
HO 5096 0412:
SAEMRSA15_06750
JH1:
SaurJH1_0790
JH9:
SaurJH9_0773
JKD6008:
SAA6008_00764
JKD6159:
SAA6159_00704
JSNZ:
JSNZ_000720 (fakB1)
LGA251:
SARLGA251_06820
M013:
M013TW_0736
MRSA252:
SAR0803
MSHR1132:
SAMSHR1132_06940
MSSA476:
SAS0714
Mu3:
SAHV_0746
Mu50:
SAV0749
MW2:
MW0711
RF122:
SAB0701
ST398:
SAPIG0825
T0131:
SAT0131_00821
TCH60:
HMPREF0772_12433
TW20:
SATW20_08240
USA300_TCH1516:
USA300HOU_0776
VC40:
—
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIP
N315 MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIP
NCTC8325 MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVT-----------------------------
Newman MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIP
USA300_FPR3757 MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIP
*******************************
COL TTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKL
N315 TTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKL
NCTC8325 ------------------------------------------------------------
Newman TTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKL
USA300_FPR3757 TTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKL
COL AAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAW
N315 AAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAW
NCTC8325 ------------------------------------------------------------
Newman AAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAW
USA300_FPR3757 AAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAW
COL VGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFED
N315 VGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFED
NCTC8325 ------------FEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFED
Newman VGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFED
USA300_FPR3757 VGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFED
************************************************
COL GQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
N315 GQALYKKLQEDCPSGYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
NCTC8325 GQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
Newman GQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
USA300_FPR3757 GQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
*********:****.*********************************
- ↑ Maxime G Cuypers, Chitra Subramanian, Jessica M Gullett, Matthew W Frank, Stephen W White, Charles O Rock
Acyl-chain selectivity and physiological roles of Staphylococcus aureus fatty acid-binding proteins.
J Biol Chem: 2019, 294(1);38-49
[PubMed:30429218] [WorldCat.org] [DOI] (I p)Joshua B Parsons, Tyler C Broussard, Jeffrey L Bose, Jason W Rosch, Pamela Jackson, Chitra Subramanian, Charles O Rock
Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus.
Proc Natl Acad Sci U S A: 2014, 111(29);10532-7
[PubMed:25002480] [WorldCat.org] [DOI] (I p)