PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN003196000
• symbol^?: murE
• synonym:
• description^?: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase

  descriptions from strain specific annotations:

  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase
  • UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase
  • UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase
  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase
  • UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-tripeptide synthetase)
• strand^?: +
• coordinates^?: 3588119..3589600
• synteny block^?: BlockID0022830
• occurrence^?: in 100% of 33 strains

⊟Orthologs

COL:
SACOL1023 (murE)
N315:
SA0876 (murE)
NCTC8325:
SAOUHSC_00954
Newman:
NWMN_0888 (murE)
USA300_FPR3757:
SAUSA300_0919 (murE)
04-02981:
SA2981_0972 (murE)
08BA02176:
C248_1042 (murE)
11819-97:
MS7_0974 (murE)
6850:
RSAU_000903 (murE)
71193:
ST398NM01_1014
ECT-R 2:
ECTR2_873 (murE)
ED133:
SAOV_0963
ED98:
SAAV_0980
HO 5096 0412:
SAEMRSA15_08480 (murE)
JH1:
SaurJH1_1035
JH9:
SaurJH9_1016
JKD6008:
SAA6008_00973 (murE)
JKD6159:
SAA6159_00874 (murE)
LGA251:
SARLGA251_09330 (murE)
M013:
M013TW_0943
MRSA252:
SAR0988 (murE)
MSHR1132:
SAMSHR1132_08650
MSSA476:
SAS0887
Mu3:
SAHV_1012 (murE)
Mu50:
SAV1018 (murE)
MW2:
MW0899 (murE)
RF122:
SAB0884 (murE)
ST398:
SAPIG1014
T0131:
SAT0131_01053 (deoC)
TCH60:
HMPREF0772_12216 (murE2)
TW20:
SATW20_10150 (murE)
USA300_TCH1516:
USA300HOU_0976 (murE1)
VC40:
SAVC_04255

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQG
  N315            MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQG
  NCTC8325        MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQG
  Newman          MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQG
  USA300_FPR3757  MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQG
                  ************************************************************
  
  COL             CKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATM
  N315            CKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATM
  NCTC8325        CKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATM
  Newman          CKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATM
  USA300_FPR3757  CKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATM
                  ************************************************************
  
  COL             IHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSS
  N315            IHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSS
  NCTC8325        IHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSS
  Newman          IHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSS
  USA300_FPR3757  IHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSS
                  ************************************************************
  
  COL             HGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNN
  N315            HGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNN
  NCTC8325        HGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNN
  Newman          HGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNN
  USA300_FPR3757  HGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNN
                  ************************************************************
  
  COL             DDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKF
  N315            DDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKF
  NCTC8325        DDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKF
  Newman          DDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKF
  USA300_FPR3757  DDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKF
                  ************************************************************
  
  COL             NISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNK
  N315            NISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNK
  NCTC8325        NISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNK
  Newman          NISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNK
  USA300_FPR3757  NISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNK
                  ************************************************************
  
  COL             LIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAEL
  N315            LIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAEL
  NCTC8325        LIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAEL
  Newman          LIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAEL
  USA300_FPR3757  LIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAEL
                  ************************************************************
  
  COL             AKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGL
  N315            AKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGL
  NCTC8325        AKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGL
  Newman          AKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGL
  USA300_FPR3757  AKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGL
                  ************************************************************
  
  COL             EAAYKKFGGGPVD-
  N315            EAAYKKFGGGPVDQ
  NCTC8325        EAAYKKFGGGPVD-
  Newman          EAAYKKFGGGPVD-
  USA300_FPR3757  EAAYKKFGGGPVD-
                  *************