PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN003769000
• symbol^?: femA
• synonym:
• description^?: aminoacyltransferase FemA

  descriptions from strain specific annotations:

  • aminoacyltransferase FemA
  • methicillin resistance protein FemA
  • Aminoacyltransferase FemA (Factor essential for expression of methicillin resistance A)
  • factor essential for expression of methicillin resistance
  • femA protein
  • glycine glycyltransferase FemA
  • methicillin resistance factor FemA
  • FemA, factor essential for methicillin resistance / Glycine interpeptide bridge formation
  • femAB family protein
  • glycine interpeptide bridge formation protein FemA
  • methicillin resistance factor, FemA
  • methicillin resistance protein
  • tRNA-dependent lipid II-Gly--glycine ligase
  • UDP-N-acetylmuramoylpentapeptide-glycine glycyltransferase
• strand^?: +
• coordinates^?: 4066368..4067707
• synteny block^?: BlockID0028310
• occurrence^?: in 100% of 33 strains

⊟Orthologs

COL:
SACOL1410 (femA)
N315:
SA1206 (femA)
NCTC8325:
SAOUHSC_01373
Newman:
NWMN_1286 (femA)
USA300_FPR3757:
SAUSA300_1269 (femA)
04-02981:
SA2981_1328 (femA)
08BA02176:
C248_1412 (femA)
11819-97:
MS7_1331
6850:
RSAU_001255 (femA)
71193:
ST398NM01_1375
ECT-R 2:
ECTR2_1231
ED133:
SAOV_1384
ED98:
SAAV_1356 (femA)
HO 5096 0412:
SAEMRSA15_12220 (femA)
JH1:
SaurJH1_1464
JH9:
SaurJH9_1435
JKD6008:
SAA6008_01339 (femA)
JKD6159:
SAA6159_01241 (femA)
LGA251:
SARLGA251_12830 (femA)
M013:
M013TW_1320
MRSA252:
SAR1387 (femA)
MSHR1132:
SAMSHR1132_12170
MSSA476:
SAS1314
Mu3:
SAHV_1362 (femA)
Mu50:
SAV1374 (femA)
MW2:
MW1261 (femA)
RF122:
SAB1229 (femA)
ST398:
SAPIG1375
T0131:
SAT0131_01446 (hlgB)
TCH60:
HMPREF0772_11833 (femA)
TW20:
SATW20_13740 (femA)
USA300_TCH1516:
USA300HOU_1309 (femA)
VC40:
SAVC_06120

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MKLINERQIGVMIMKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKN
  N315            -------------MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKN
  NCTC8325        -------------MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKN
  Newman          -------------MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKN
  USA300_FPR3757  MKLINERQIGVMIMKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKN
                               ***********************************************
  
  COL             NNNEVIAACLLTAVPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHI
  N315            NNNEVIAACLLTAVPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHI
  NCTC8325        NNNEVIAACLLTAVPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHI
  Newman          NNNEVIAACLLTAVPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHI
  USA300_FPR3757  NNNEVIAACLLTAVPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHI
                  ************************************************************
  
  COL             DPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKT
  N315            DPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKT
  NCTC8325        DPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKT
  Newman          DPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKT
  USA300_FPR3757  DPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKT
                  ************************************************************
  
  COL             ADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSESKAFADRDDKFYYN
  N315            ADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDTSESKAFADRDDKFYYN
  NCTC8325        ADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSESKAFADRDDKFYYN
  Newman          ADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSESKAFADRDDKFYYN
  USA300_FPR3757  ADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSESKAFADRDDKFYYN
                  ***************************:********************************
  
  COL             RLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQ
  N315            RLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQ
  NCTC8325        RLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQ
  Newman          RLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQ
  USA300_FPR3757  RLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQ
                  ************************************************************
  
  COL             QQLDANEQKIEEGKRLQEEHGNELPISAGFFFINPFEVVYYAGGTSNAFRHFAGSYAVQW
  N315            QQLDANEQKIEEGKRLQEEHGNELPISAGFFFINPFEVVYYAGGTSNAFRHFAGSYAVQW
  NCTC8325        QQLDANEQKIEEGKRLQEEHGNELPISAGFFFINPFEVVYYAGGTSNAFRHFAGSYAVQW
  Newman          QQLDANEQKIEEGKRLQEEHGNELPISAGFFFINPFEVVYYAGGTSNAFRHFAGSYAVQW
  USA300_FPR3757  QQLDANEQKIEEGKRLQEEHGNELPISAGFFFINPFEVVYYAGGTSNAFRHFAGSYAVQW
                  ************************************************************
  
  COL             EMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYA
  N315            EMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYA
  NCTC8325        EMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYA
  Newman          EMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYA
  USA300_FPR3757  EMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYA
                  ************************************************************
  
  COL             AYTALKKVKDRIF
  N315            AYTALKKVKDRIF
  NCTC8325        AYTALKKVKDRIF
  Newman          AYTALKKVKDRIF
  USA300_FPR3757  AYTALKKVKDRIF
                  *************