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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40
⊟Summary[edit | edit source]
- pan ID?: SAUPAN004095000
- symbol?: —
- synonym:
- description?: cell division protein FtsK
- cell division protein FtsK
- FtsK/SpoIIIE family protein
- FtsK/SpoIIIE family cell division protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4372902..4374588
- synteny block?: BlockID0031250
- occurrence?: in 26% of 34 strains
virD4 : ICE6013 coupling protein ATPase VirD4 [1]
Some staphylococci have acquired a Type IV secretion system encoded on an integrative conjugative element (ICE6013), which encodes a minimal conjugative transfer function that may have adapted to double as a small molecule translocation system. Coupling protein ATPases are cytoplasmic proteins that identify cargo to be translocated and guide it to the relaxasome complex via their interaction with VirB4 ATPases. The cargo can then be directly transferred through the translocase channel or attached to Relaxase for facilitated transport through the translocase channel.
⊟Orthologs[edit | edit source]
04-02981:
—
08BA02176:
—
11819-97:
—
6850:
—
71193:
—
ECT-R 2:
—
ED133:
—
ED98:
—
HO 5096 0412:
SAEMRSA15_12350
JH1:
—
JH9:
—
JKD6008:
SAA6008_02635
JKD6159:
—
JSNZ:
—
LGA251:
—
M013:
—
MRSA252:
SAR1292
MSHR1132:
SAMSHR1132_15350
MSSA476:
—
Mu3:
—
Mu50:
—
MW2:
—
RF122:
—
ST398:
—
T0131:
SAT0131_02810 (thrB)
TCH60:
—
TW20:
SATW20_27170
USA300_TCH1516:
USA300HOU_0630
VC40:
—
⊟Genome Viewer[edit | edit source]
| COL | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MAMNEIALFKGVRIQPYQKYIDFMFASVLAFIFLVYRIYILFIDYKSVNKKLDILTLFAY
USA300_FPR3757 MAMNEIALFKGVRIQPYQKYIDFMFASVLAFIFLVYRIYILFIDYKSVNKKLDILTLFAY
************************************************************
COL FKPHLLYLLIGTAIIFVICKLIAQLLIRFKTKDLAEMIETQGFHNRTVIKKTTEYIPIDY
USA300_FPR3757 FKPHLLYLLIGTAIIFVICKLIAQFLIRFKTKDLAEMIETQGFHNRTVIKKTTEYIPIDY
************************:***********************************
COL KQTEYDYYPTMFYKRGKKTFVIHIKKDGSRFQDNYLELETIIEPMFNSELVEKKHIGRYL
USA300_FPR3757 KQTEYDYYPTMFYKRGKKSFVIHIKKDGSRFQDNYLELETIIEPMFNSELVEKKHIGRYL
******************:*****************************************
COL RYEFMPLKYKKRIVMNGEQESNTIFYDTKIAITHQITWDFVKAPHGLVTGITGGGKTYFL
USA300_FPR3757 RYEFMPLKYKKRIVMNGEQESNTIFYDTKIAITHQITWDFVKAPHGLVTGITGGGKTYFL
************************************************************
COL FYVIRELFRRHSEVRLLDPKVSDLSFMKRVIGDDKVADTKGQILKQLREANNEMEERFRL
USA300_FPR3757 FYVIRELFRRHSEVRLLDPKVSDLSFMKRVIGDDKVADTKGQILKQLREANNEMEERFRL
************************************************************
COL MNDSSDYKIGNDFRNFDMRPYFIIFDEVTAFTSTLDKKELQEMNDYLINIIMKGRQAGVF
USA300_FPR3757 MNDSSDYKIGNDFRNFDMRPYFIIFDEVTAFTSTLDKKELQEMNDYLINIIMKGRQAGVF
************************************************************
COL MFLTAQRPDADVIKGNVRDQLGLRVSLGNLSNDGYRMTFGQTDKEFQTIHDSDIGRGYIT
USA300_FPR3757 MFLTAQRPDADVIKGNVRDQLGLRVSLGNLSNDGYRMTFGQTDKEFQTIHDSDIGRGYIS
***********************************************************:
COL ILGQYNEPILFDAPLMEQYDFVEDVKQILNKE
USA300_FPR3757 ILGQYNEPILFDAPLMEQYDFVEDVKQILNKE
********************************
- ↑ Zita Nagy, Mónika Szabó, Michael Chandler, Ferenc Olasz
Analysis of the N-terminal DNA binding domain of the IS30 transposase.
Mol Microbiol: 2004, 54(2);478-88
[PubMed:15469518] [WorldCat.org] [DOI] (P p)Davida S Smyth, D Ashley Robinson
Integrative and sequence characteristics of a novel genetic element, ICE6013, in Staphylococcus aureus.
J Bacteriol: 2009, 191(19);5964-75
[PubMed:19648240] [WorldCat.org] [DOI] (I p)Minny Bhatty, Jenny A Laverde Gomez, Peter J Christie
The expanding bacterial type IV secretion lexicon.
Res Microbiol: 2013, 164(6);620-39
[PubMed:23542405] [WorldCat.org] [DOI] (I p)Emily A Sansevere, Xiao Luo, Joo Youn Park, Sunghyun Yoon, Keun Seok Seo, D Ashley Robinson
Transposase-Mediated Excision, Conjugative Transfer, and Diversity of ICE6013 Elements in Staphylococcus aureus.
J Bacteriol: 2017, 199(8);
[PubMed:28138100] [WorldCat.org] [DOI] (I e)