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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004577000
- symbol?: epiC
- synonym:
- description?: lanthionine synthetase
- lanthionine synthetase
- epidermin biosynthesis protein EpiC
- lantibiotic biosynthesis protein
- lantibiotic epidermin biosynthesis protein EpiC
- epidermin biosynthesis protein EpiC, authentic point mutation
- lanthionine synthetase C-like family protein
- pseudogene
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4809143..4819619
- synteny block?: BlockID0035600
- occurrence?: in 42% of 33 strains
bsaC: bacteriocin of Staphylococcus aureus posttranslational lanthionine synthetase [1]
⊟Orthologs[edit | edit source]
04-02981:
—
08BA02176:
—
11819-97:
MS7_1821
6850:
—
71193:
—
ECT-R 2:
—
ED133:
SAOV_1805
ED98:
—
HO 5096 0412:
—
JH1:
—
JH9:
—
JKD6008:
—
JKD6159:
—
LGA251:
SARLGA251_17040
M013:
—
MRSA252:
—
MSHR1132:
—
MSSA476:
SAS1744
Mu3:
—
Mu50:
—
MW2:
MW1763 (bsaC)
RF122:
SAB1681c
ST398:
—
T0131:
SAT0131_01942
TCH60:
—
TW20:
SATW20_18180
USA300_TCH1516:
USA300HOU_1813 (epiC)
VC40:
SAVC_08340
⊟Genome Viewer[edit | edit source]
| COL | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
NCTC8325 MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTE
Newman MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTE
USA300_FPR3757 MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTE
************************************************************
NCTC8325 QIVHKYIMKLAPYLQSGQYNNSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIE
Newman QIVHKYIMKLAPYLQSGQYNNSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIE
USA300_FPR3757 QIVHKYIMKLAPYLQSGQYNNSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIE
************************************************************
NCTC8325 NKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNVKALKSILVYFKDIQYSKNSW
Newman NKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNVKALKSILVYFKDIQYSKNSW
USA300_FPR3757 NKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNVKALKSILVYFKDIQYSKNSW
************************************************************
NCTC8325 VVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
Newman VVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
USA300_FPR3757 VVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
************************************************************
NCTC8325 MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKK
Newman MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKK
USA300_FPR3757 MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKK
************************************************************
NCTC8325 VMLQVVNDKDENLISPTICHGLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDY
Newman VMLQVVNDKDENLISPTICHGLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDY
USA300_FPR3757 VMLQVVNDKDENLISPTICHGLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDY
************************************************************
NCTC8325 LVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTKILNEKNWTNAFLIS
Newman LVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTKILNEKNWTNAFLIS
USA300_FPR3757 LVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTKILNEKNWTNAFLIS
******************************************************
- ↑ Karen M Daly, Mathew Upton, Stephanie K Sandiford, Lorraine A Draper, Philip A Wescombe, Ralph W Jack, Paula M O'Connor, Angela Rossney, Friedrich Götz, Colin Hill, Paul D Cotter, R Paul Ross, John R Tagg
Production of the Bsa lantibiotic by community-acquired Staphylococcus aureus strains.
J Bacteriol: 2010, 192(4);1131-42
[PubMed:20023032] [WorldCat.org] [DOI] (I p)Leon D Kluskens, Anneke Kuipers, Rick Rink, Esther de Boef, Susan Fekken, Arnold J M Driessen, Oscar P Kuipers, Gert N Moll
Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin.
Biochemistry: 2005, 44(38);12827-34
[PubMed:16171398] [WorldCat.org] [DOI] (P p)